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Conserved domains on  [gi|21704281|ref|NP_065166|]
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junctophilin-2 isoform 1 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
2-143 6.90e-27

Uncharacterized conserved protein [Function unknown];


:

Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 110.43  E-value: 6.90e-27
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281   2 SGGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGqGEYSGSWNFG-FEVAGVYTWPSGNTFEGYWSQGKRHGLGIET-KGR 79
Cdd:COG4642 115 GGGVLEGDDGGGYGGGTADGGRGGGGIYTFPNG-DVYEGEFKNGkPHGQGTLTYADGDRYEGEFKNGKRHGQGTLTyANG 193

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 21704281  80 WLYKGEWTHGF---KGRYgirqSSSSGAKYEGTWNNGLQDGYGTETYADGGTYQGQFTNGMRHGYGV 143
Cdd:COG4642 194 DVYEGEFKNGQrhgQGTY----TYADGDRYEGEFKNGKRHGQGTLTYADGDRYEGEFKNGKRHGQGT 256
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 444-642 2.12e-05

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.01  E-value: 2.12e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281   444 ENSESLLEPPDRGAGAAGLPQPPRESPQLHERETPRPEGGSPSPAGTPPQPKRPRPGVSKDGLLSPGawnGEPSGEGSRS 523
Cdd:PHA03247 2793 ESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPG---GDVRRRPPSR 2869

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281   524 VTPSEGAGRRSP-----ARPATERMAIEALQAPPAPSREPEVALYQgyhsyAVRTTPPEPPPFEDQPEPEVSGSESAPSS 598
Cdd:PHA03247 2870 SPAAKPAAPARPpvrrlARPAVSRSTESFALPPDQPERPPQPQAPP-----PPQPQPQPPPPPQPQPPPPPPPRPQPPLA 2944

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 21704281   599 PATAPLQAPTLRGPEPARETPAKLEPKPIIPK--AEPRAKARKTEA 642
Cdd:PHA03247 2945 PTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRfrVPQPAPSREAPA 2990
PLN03185 super family cl33654
phosphatidylinositol phosphate kinase; Provisional
 101-334 1.05e-04

phosphatidylinositol phosphate kinase; Provisional


The actual alignment was detected with superfamily member PLN03185:

Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 45.59  E-value: 1.05e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281  101 SSGAKYEGTWNNGLQDGYGTETYADGGTYQGQFTNGMRHGYGvRQSVPYGmavvvrsplrtslSSLRSEHSngtvapdsp 180
Cdd:PLN03185   6 SNGDFYSGSLLGNVPEGPGKYLWSDGCMYEGEWRRGMRHGNG-KISWPSG-------------ATYEGEFS--------- 62

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281  181 aspasdgpalpspaiprGGFALSLLANAEAAARAPKGGGLFQRGALLGKLRRAESRTSVGS--QRSRVSFLKSDLSSGas 258
Cdd:PLN03185  63 -----------------GGYMHGSGTYTGTDGTTYKGRWRLNLKHGLGYQRYPNGDVFEGSwiQGLQEGPGKYTWANG-- 123

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 21704281  259 daastaslgeaaegadeaapfeadidatttETYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGCTTLPDG 334
Cdd:PLN03185 124 ------------------------------NVYLGDMKGGKMSGKGTLTWVSGDSYEGQWLDGMMHGFGVYTWSDG 169
 
Name Accession Description Interval E-value
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
2-143 6.90e-27

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 110.43  E-value: 6.90e-27
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281   2 SGGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGqGEYSGSWNFG-FEVAGVYTWPSGNTFEGYWSQGKRHGLGIET-KGR 79
Cdd:COG4642 115 GGGVLEGDDGGGYGGGTADGGRGGGGIYTFPNG-DVYEGEFKNGkPHGQGTLTYADGDRYEGEFKNGKRHGQGTLTyANG 193

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 21704281  80 WLYKGEWTHGF---KGRYgirqSSSSGAKYEGTWNNGLQDGYGTETYADGGTYQGQFTNGMRHGYGV 143
Cdd:COG4642 194 DVYEGEFKNGQrhgQGTY----TYADGDRYEGEFKNGKRHGQGTLTYADGDRYEGEFKNGKRHGQGT 256
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 4-143 3.28e-19

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 92.20  E-value: 3.28e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281    4 GRFDFDDGGAYCGGWEGGKAHGHGLCTGPKG---QGEYSGSWNFGFevaGVYTWPSGNTFEGYWSQGKRHGLGIET---- 76
Cdd:PLN03185  24 GKYLWSDGCMYEGEWRRGMRHGNGKISWPSGatyEGEFSGGYMHGS---GTYTGTDGTTYKGRWRLNLKHGLGYQRypng 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281   77 ---KGRWL-----------------YKGEWTHGFKGRYGIRqSSSSGAKYEGTWNNGLQDGYGTETYADGGTYQGQFTNG 136
Cdd:PLN03185 101 dvfEGSWIqglqegpgkytwangnvYLGDMKGGKMSGKGTL-TWVSGDSYEGQWLDGMMHGFGVYTWSDGGCYVGTWTRG 179


                 ....*..
gi 21704281  137 MRHGYGV 143
Cdd:PLN03185 180 LKDGKGV 186
PHA03247 PHA03247
large tegument protein UL36; Provisional
 444-642 2.12e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.01  E-value: 2.12e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281   444 ENSESLLEPPDRGAGAAGLPQPPRESPQLHERETPRPEGGSPSPAGTPPQPKRPRPGVSKDGLLSPGawnGEPSGEGSRS 523
Cdd:PHA03247 2793 ESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPG---GDVRRRPPSR 2869

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281   524 VTPSEGAGRRSP-----ARPATERMAIEALQAPPAPSREPEVALYQgyhsyAVRTTPPEPPPFEDQPEPEVSGSESAPSS 598
Cdd:PHA03247 2870 SPAAKPAAPARPpvrrlARPAVSRSTESFALPPDQPERPPQPQAPP-----PPQPQPQPPPPPQPQPPPPPPPRPQPPLA 2944

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 21704281   599 PATAPLQAPTLRGPEPARETPAKLEPKPIIPK--AEPRAKARKTEA 642
Cdd:PHA03247 2945 PTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRfrVPQPAPSREAPA 2990
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 101-334 1.05e-04

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 45.59  E-value: 1.05e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281  101 SSGAKYEGTWNNGLQDGYGTETYADGGTYQGQFTNGMRHGYGvRQSVPYGmavvvrsplrtslSSLRSEHSngtvapdsp 180
Cdd:PLN03185   6 SNGDFYSGSLLGNVPEGPGKYLWSDGCMYEGEWRRGMRHGNG-KISWPSG-------------ATYEGEFS--------- 62

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281  181 aspasdgpalpspaiprGGFALSLLANAEAAARAPKGGGLFQRGALLGKLRRAESRTSVGS--QRSRVSFLKSDLSSGas 258
Cdd:PLN03185  63 -----------------GGYMHGSGTYTGTDGTTYKGRWRLNLKHGLGYQRYPNGDVFEGSwiQGLQEGPGKYTWANG-- 123

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 21704281  259 daastaslgeaaegadeaapfeadidatttETYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGCTTLPDG 334
Cdd:PLN03185 124 ------------------------------NVYLGDMKGGKMSGKGTLTWVSGDSYEGQWLDGMMHGFGVYTWSDG 169
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 106-128 1.23e-04

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 39.31  E-value: 1.23e-04
                          10        20
                  ....*....|....*....|...
gi 21704281   106 YEGTWNNGLQDGYGTETYADGGT 128
Cdd:pfam02493   1 YEGEWKNGKRHGKGVYTWPDGDR 23
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 314-336 4.18e-04

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 37.77  E-value: 4.18e-04
                          10        20
                  ....*....|....*....|...
gi 21704281   314 YEGEWLDNLRHGYGCTTLPDGHR 336
Cdd:pfam02493   1 YEGEWKNGKRHGKGVYTWPDGDR 23
SepH NF040712
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ...
 473-637 7.47e-04

septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.


Pssm-ID: 468676 [Multi-domain]  Cd Length: 346  Bit Score: 42.45  E-value: 7.47e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281  473 HERETPRPEGGSPSPAG------TPPQPKRPRPGVSKDGLLSPGAWNGEPSGEGSRSVTPSEGAGRRSPARPATERMAIE 546
Cdd:NF040712 165 HWTFDPGAHGGTVTALDdearwlIDPDFGRPLRPLATVPRLAREPADARPEEVEPAPAAEGAPATDSDPAEAGTPDDLAS 244

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281  547 ALQAPPAPSREPEVALYQGYHSYAVRTTPPEPPPFEDQPEPEVSGSESAPSSPATAPLQAPTlrgpEPARETPAKLEPKP 626
Cdd:NF040712 245 ARRRRAGVEQPEDEPVGPGAAPAAEPDEATRDAGEPPAPGAAETPEAAEPPAPAPAAPAAPA----APEAEEPARPEPPP 320

                        170
                 ....*....|.
gi 21704281  627 IIPKAEPRAKA 637
Cdd:NF040712 321 APKPKRRRRRA 331
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
313-333 7.59e-04

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 37.32  E-value: 7.59e-04
                           10        20
                   ....*....|....*....|.
gi 21704281    313 RYEGEWLDNLRHGYGCTTLPD 333
Cdd:smart00698   2 RYEGEWRNGKRHGRGVYTYAN 22
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
104-125 3.79e-03

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 35.01  E-value: 3.79e-03
                           10        20
                   ....*....|....*....|..
gi 21704281    104 AKYEGTWNNGLQDGYGTETYAD 125
Cdd:smart00698   1 DRYEGEWRNGKRHGRGVYTYAN 22
 
Name Accession Description Interval E-value
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
2-143 6.90e-27

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 110.43  E-value: 6.90e-27
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281   2 SGGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGqGEYSGSWNFG-FEVAGVYTWPSGNTFEGYWSQGKRHGLGIET-KGR 79
Cdd:COG4642 115 GGGVLEGDDGGGYGGGTADGGRGGGGIYTFPNG-DVYEGEFKNGkPHGQGTLTYADGDRYEGEFKNGKRHGQGTLTyANG 193

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 21704281  80 WLYKGEWTHGF---KGRYgirqSSSSGAKYEGTWNNGLQDGYGTETYADGGTYQGQFTNGMRHGYGV 143
Cdd:COG4642 194 DVYEGEFKNGQrhgQGTY----TYADGDRYEGEFKNGKRHGQGTLTYADGDRYEGEFKNGKRHGQGT 256
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
2-135 2.05e-23

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 100.42  E-value: 2.05e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281   2 SGGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGqGEYSGSWNFG-FEVAGVYTWPSGNTFEGYWSQGKRHGLGIET-KGR 79
Cdd:COG4642 138 GGGIYTFPNGDVYEGEFKNGKPHGQGTLTYADG-DRYEGEFKNGkRHGQGTLTYANGDVYEGEFKNGQRHGQGTYTyADG 216

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 21704281  80 WLYKGEWTHGF---KGRYgirqSSSSGAKYEGTWNNGLQDGYGTETYADGGTYQGQFTN 135
Cdd:COG4642 217 DRYEGEFKNGKrhgQGTL----TYADGDRYEGEFKNGKRHGQGTMTYADGSVYEGEWKN 271
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
3-143 2.57e-23

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 100.03  E-value: 2.57e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281   3 GGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGVYTWPSGNTFEGYWSQGKRHGLGIETkgrwly 82
Cdd:COG4642  93 GGEGGFGGGGGGGGGKKGGGGGGGGVLEGDDGGGYGGGTADGGRGGGGIYTFPNGDVYEGEFKNGKPHGQGTLT------ 166

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 21704281  83 kgewthgfkgrygirqsSSSGAKYEGTWNNGLQDGYGTETYADGGTYQGQFTNGMRHGYGV 143
Cdd:COG4642 167 -----------------YADGDRYEGEFKNGKRHGQGTLTYANGDVYEGEFKNGQRHGQGT 210
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 4-143 3.28e-19

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 92.20  E-value: 3.28e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281    4 GRFDFDDGGAYCGGWEGGKAHGHGLCTGPKG---QGEYSGSWNFGFevaGVYTWPSGNTFEGYWSQGKRHGLGIET---- 76
Cdd:PLN03185  24 GKYLWSDGCMYEGEWRRGMRHGNGKISWPSGatyEGEFSGGYMHGS---GTYTGTDGTTYKGRWRLNLKHGLGYQRypng 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281   77 ---KGRWL-----------------YKGEWTHGFKGRYGIRqSSSSGAKYEGTWNNGLQDGYGTETYADGGTYQGQFTNG 136
Cdd:PLN03185 101 dvfEGSWIqglqegpgkytwangnvYLGDMKGGKMSGKGTL-TWVSGDSYEGQWLDGMMHGFGVYTWSDGGCYVGTWTRG 179


                 ....*..
gi 21704281  137 MRHGYGV 143
Cdd:PLN03185 180 LKDGKGV 186
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
9-346 1.13e-18

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 86.55  E-value: 1.13e-18
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281   9 DDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGVYTWPSGNTFEGYWSQGKRHGLGIETKGRWLY---KGE 85
Cdd:COG4642  41 PGGGGYGGGADGGGGGGGGTGVAGGGGGEGGVTAAGGGGGGGGGKGDGGDGGGGEGGFGGGGGGGGGKKGGGGGgggVLE 120

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281  86 WTHGFKGRYGIRQSS---------SSGAKYEGTWNNGLQDGYGTETYADGGTYQGQFTNGMRHGYGVRQsvpygmavvvr 156
Cdd:COG4642 121 GDDGGGYGGGTADGGrggggiytfPNGDVYEGEFKNGKPHGQGTLTYADGDRYEGEFKNGKRHGQGTLT----------- 189

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281 157 splrtslsslrseHSNGTVapdspaspasdgpalpspaiprggfalsllanaeaaarapkggglfqrgallgklrraesr 236
Cdd:COG4642 190 -------------YANGDV------------------------------------------------------------- 195

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281 237 tsvgsqrsrvsflksdlssgasdaastaslgeaaegadeaapfeadidatttetYMGEWKNDKRSGFGVSERSSGLRYEG 316
Cdd:COG4642 196 ------------------------------------------------------YEGEFKNGQRHGQGTYTYADGDRYEG 221

                       330       340       350
                ....*....|....*....|....*....|
gi 21704281 317 EWLDNLRHGYGCTTLPDGHREEGKYRHNVL 346
Cdd:COG4642 222 EFKNGKRHGQGTLTYADGDRYEGEFKNGKR 251
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 38-150 2.93e-11

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 66.78  E-value: 2.93e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281   38 YSGSWNFGF-EVAGVYTWPSGNTFEGYWSQGKRHGLGietKGRWlykgewthgfkgrygirqssSSGAKYEGTWNNGLQD 116
Cdd:PLN03185  11 YSGSLLGNVpEGPGKYLWSDGCMYEGEWRRGMRHGNG---KISW--------------------PSGATYEGEFSGGYMH 67

                         90       100       110
                 ....*....|....*....|....*....|....
gi 21704281  117 GYGTETYADGGTYQGQFTNGMRHGYGvRQSVPYG 150
Cdd:PLN03185  68 GSGTYTGTDGTTYKGRWRLNLKHGLG-YQRYPNG 100
PHA03247 PHA03247
large tegument protein UL36; Provisional
 444-642 2.12e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.01  E-value: 2.12e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281   444 ENSESLLEPPDRGAGAAGLPQPPRESPQLHERETPRPEGGSPSPAGTPPQPKRPRPGVSKDGLLSPGawnGEPSGEGSRS 523
Cdd:PHA03247 2793 ESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPG---GDVRRRPPSR 2869

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281   524 VTPSEGAGRRSP-----ARPATERMAIEALQAPPAPSREPEVALYQgyhsyAVRTTPPEPPPFEDQPEPEVSGSESAPSS 598
Cdd:PHA03247 2870 SPAAKPAAPARPpvrrlARPAVSRSTESFALPPDQPERPPQPQAPP-----PPQPQPQPPPPPQPQPPPPPPPRPQPPLA 2944

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 21704281   599 PATAPLQAPTLRGPEPARETPAKLEPKPIIPK--AEPRAKARKTEA 642
Cdd:PHA03247 2945 PTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRfrVPQPAPSREAPA 2990
PHA03247 PHA03247
large tegument protein UL36; Provisional
 416-638 2.43e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.01  E-value: 2.43e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281   416 RTLARELAPDFYQPgPEYQKRRLLQEILENSESLLEPPDRgagaaglPQPPRESPQLHERETPRPEGGSPSPAGTPPQPK 495
Cdd:PHA03247 2666 RARRLGRAAQASSP-PQRPRRRAARPTVGSLTSLADPPPP-------PPTPEPAPHALVSATPLPPGPAAARQASPALPA 2737

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281   496 RPRPGVSKDGLLSPGAWNGE-----PSGEGSRS--VTPSEGAGRRSPARP-ATERMAIEALQAPPAPSREPEVALyqgyh 567
Cdd:PHA03247 2738 APAPPAVPAGPATPGGPARParpptTAGPPAPAppAAPAAGPPRRLTRPAvASLSESRESLPSPWDPADPPAAVL----- 2812

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 21704281   568 syaVRTTPPEPPPFEDQPEPEVSGSESAPSSPATAPLQAPTLRGPEPARETPAKLEPKPIIPKAEPRAKAR 638
Cdd:PHA03247 2813 ---APAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPAR 2880
YwqK COG2849
Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];
36-139 3.17e-05

Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];


Pssm-ID: 442097 [Multi-domain]  Cd Length: 163  Bit Score: 44.67  E-value: 3.17e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281  36 GEYSGSWNFGFEVAGVYTW--PSGN-TFEGYWSQGKRHGLGIE--TKGRWLYKGEWTHGFK-GRYgiRQSSSSGA-KYEG 108
Cdd:COG2849  54 KLGKGLGKYKKGKLGEWKTyyPNGQlKSEGTYKNGKLEGEWKEyyENGKLKSEGNYKNGKLhGEW--KEYYENGKlKEEG 131

                        90       100       110
                ....*....|....*....|....*....|..
gi 21704281 109 TWNNGLQDGYGTETYADGG-TYQGQFTNGMRH 139
Cdd:COG2849 132 NYKNGKKDGVWKYYDENGKlVKEEEYKNGKKV 163
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
453-644 5.39e-05

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 46.77  E-value: 5.39e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281  453 PDRGAGAAGLPQPPRESPQLHERETPRPEGGSP-SPAGTPPQPKRPRPGVSKDGLLSPGAWNGEPSGEGSRSVTPSEGAG 531
Cdd:PRK07003 385 ARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAaAATRAEAPPAAPAPPATADRGDDAADGDAPVPAKANARASADSRCD 464

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281  532 RRSPARPATERM-AIEALQAPPAPSREPEVALYQGYHSYAVRTTPPEPPPFEDQPEPEVSGSESAPSSPATAPLQA-PTL 609
Cdd:PRK07003 465 ERDAQPPADSGSaSAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASREDAPAAAAPPAPEARPPTPAAAaPAA 544

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 21704281  610 RG---------------------------------PEPARETPAKlePKPIIPKAEPRAKARKTEARG 644
Cdd:PRK07003 545 RAggaaaaldvlrnagmrvssdrgaraaaaakpaaAPAAAPKPAA--PRVAVQVPTPRARAATGDAPP 610
PHA03247 PHA03247
large tegument protein UL36; Provisional
 418-642 8.39e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 46.08  E-value: 8.39e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281   418 LARELAPDFYQPGPEYQKRRLLQEILENSESLLEPPDRGAGAAglPQPPRESPqlheRETPRPEGGSPSPAGTPPQPKRP 497
Cdd:PHA03247 2558 AAPPAAPDRSVPPPRPAPRPSEPAVTSRARRPDAPPQSARPRA--PVDDRGDP----RGPAPPSPLPPDTHAPDPPPPSP 2631

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281   498 RPGVSKDGLLSPGAWNGEPSGEGS----------RSVTPSEGAGRRSPARPATERMA------IEALQAPPAPSREPEVA 561
Cdd:PHA03247 2632 SPAANEPDPHPPPTVPPPERPRDDpapgrvsrprRARRLGRAAQASSPPQRPRRRAArptvgsLTSLADPPPPPPTPEPA 2711

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281   562 LyqgyHSYAVRTTPPEPPPFEDQPEPEVSGSESAPSSPATAPLQA-PTLRGPEPARETPAKLEPKPIIPKAEPRAKARKT 640
Cdd:PHA03247 2712 P----HALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGgPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPA 2787


                  ..
gi 21704281   641 EA 642
Cdd:PHA03247 2788 VA 2789
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 452-559 9.81e-05

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 45.75  E-value: 9.81e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281  452 PPDRGAGAAGLPQPPRESPQlheRETPRPEGGSPSPAGTPPQPKRPRPGVSKDGLLSPGAWNGEPSGEGSRSVTPSEGAG 531
Cdd:PRK07764 397 AAPSAAAAAPAAAPAPAAAA---PAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAA 473

                         90       100
                 ....*....|....*....|....*...
gi 21704281  532 RRSPARPATERMAIEALQAPPAPSREPE 559
Cdd:PRK07764 474 PEPTAAPAPAPPAAPAPAAAPAAPAAPA 501
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 101-334 1.05e-04

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 45.59  E-value: 1.05e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281  101 SSGAKYEGTWNNGLQDGYGTETYADGGTYQGQFTNGMRHGYGvRQSVPYGmavvvrsplrtslSSLRSEHSngtvapdsp 180
Cdd:PLN03185   6 SNGDFYSGSLLGNVPEGPGKYLWSDGCMYEGEWRRGMRHGNG-KISWPSG-------------ATYEGEFS--------- 62

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281  181 aspasdgpalpspaiprGGFALSLLANAEAAARAPKGGGLFQRGALLGKLRRAESRTSVGS--QRSRVSFLKSDLSSGas 258
Cdd:PLN03185  63 -----------------GGYMHGSGTYTGTDGTTYKGRWRLNLKHGLGYQRYPNGDVFEGSwiQGLQEGPGKYTWANG-- 123

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 21704281  259 daastaslgeaaegadeaapfeadidatttETYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGCTTLPDG 334
Cdd:PLN03185 124 ------------------------------NVYLGDMKGGKMSGKGTLTWVSGDSYEGQWLDGMMHGFGVYTWSDG 169
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 106-128 1.23e-04

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 39.31  E-value: 1.23e-04
                          10        20
                  ....*....|....*....|...
gi 21704281   106 YEGTWNNGLQDGYGTETYADGGT 128
Cdd:pfam02493   1 YEGEWKNGKRHGKGVYTWPDGDR 23
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
478-646 2.06e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 44.84  E-value: 2.06e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281  478 PRPEGGSPSPAGTPPQPKRPRPGvskdgllsPGAWNGEPSGEGSRSVTPSEGAGRRSPARPATermaieALQAPPAPSRE 557
Cdd:PRK07003 360 PAVTGGGAPGGGVPARVAGAVPA--------PGARAAAAVGASAVPAVTAVTGAAGAALAPKA------AAAAAATRAEA 425

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281  558 PEVALYQGYHSYAVRTTPPEPPPFEDQPEPEVSGSESAPSSPATAPLQAPTLRGPEPARETPAKLEPKPIIPKAEPRAKA 637
Cdd:PRK07003 426 PPAAPAPPATADRGDDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPA 505


                 ....*....
gi 21704281  638 RKTEARGLT 646
Cdd:PRK07003 506 AVPDARAPA 514
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 290-345 2.92e-04

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 44.05  E-value: 2.92e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 21704281  290 TYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGCTTLPDGHREEGKYRHNV 345
Cdd:PLN03185  33 MYEGEWRRGMRHGNGKISWPSGATYEGEFSGGYMHGSGTYTGTDGTTYKGRWRLNL 88
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 314-336 4.18e-04

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 37.77  E-value: 4.18e-04
                          10        20
                  ....*....|....*....|...
gi 21704281   314 YEGEWLDNLRHGYGCTTLPDGHR 336
Cdd:pfam02493   1 YEGEWKNGKRHGKGVYTWPDGDR 23
SepH NF040712
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ...
 473-637 7.47e-04

septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.


Pssm-ID: 468676 [Multi-domain]  Cd Length: 346  Bit Score: 42.45  E-value: 7.47e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281  473 HERETPRPEGGSPSPAG------TPPQPKRPRPGVSKDGLLSPGAWNGEPSGEGSRSVTPSEGAGRRSPARPATERMAIE 546
Cdd:NF040712 165 HWTFDPGAHGGTVTALDdearwlIDPDFGRPLRPLATVPRLAREPADARPEEVEPAPAAEGAPATDSDPAEAGTPDDLAS 244

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281  547 ALQAPPAPSREPEVALYQGYHSYAVRTTPPEPPPFEDQPEPEVSGSESAPSSPATAPLQAPTlrgpEPARETPAKLEPKP 626
Cdd:NF040712 245 ARRRRAGVEQPEDEPVGPGAAPAAEPDEATRDAGEPPAPGAAETPEAAEPPAPAPAAPAAPA----APEAEEPARPEPPP 320

                        170
                 ....*....|.
gi 21704281  627 IIPKAEPRAKA 637
Cdd:NF040712 321 APKPKRRRRRA 331
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
313-333 7.59e-04

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 37.32  E-value: 7.59e-04
                           10        20
                   ....*....|....*....|.
gi 21704281    313 RYEGEWLDNLRHGYGCTTLPD 333
Cdd:smart00698   2 RYEGEWRNGKRHGRGVYTYAN 22
PHA03378 PHA03378
EBNA-3B; Provisional
 450-561 8.00e-04

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 42.75  E-value: 8.00e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281  450 LEPPDRGAGaaglPQPPRESPQLHERETPRPEGGSPSPAGTPPQPKRPR--PGVSKDGLLSPGAWNgEPSGEGSRSVTPS 527
Cdd:PHA03378 694 MQPPPRAPT----PMRPPAAPPGRAQRPAAATGRARPPAAAPGRARPPAaaPGRARPPAAAPGRAR-PPAAAPGRARPPA 768

                         90       100       110
                 ....*....|....*....|....*....|....
gi 21704281  528 EGAGRRSPARPAtermaiealQAPPAPSREPEVA 561
Cdd:PHA03378 769 AAPGAPTPQPPP---------QAPPAPQQRPRGA 793
PHA03247 PHA03247
large tegument protein UL36; Provisional
 436-557 8.27e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.00  E-value: 8.27e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281   436 RRLLQEILENS-ESLLEPPDRGAgaaglPQPPRESPQlhERETPRPEGGSPSPAGTPPQPKRPRPGVSKDGLLSPGawnG 514
Cdd:PHA03247 2884 RRLARPAVSRStESFALPPDQPE-----RPPQPQAPP--PPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGA---G 2953

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 21704281   515 EPSGegsrsVTPSEGAGRRSPARPATERMAIealqAPPAPSRE 557
Cdd:PHA03247 2954 EPSG-----AVPQPWLGALVPGRVAVPRFRV----PQPAPSRE 2987
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
452-642 8.86e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 42.56  E-value: 8.86e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281  452 PPDRGAGAAGLPQPPRESPQLherETPRPEGGSPSPAGTPPQPKRPRPGVSKDGLLSPGawngePSGEGSRSVTPSEGAG 531
Cdd:PRK12323 374 PATAAAAPVAQPAPAAAAPAA---AAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPA-----PEALAAARQASARGPG 445

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281  532 RRSPARPATERMAIEALQAPPAPSREPEVALYQGYHSYAVRTTPPEPPPF--------EDQPEPEVSGSESAPSSPATAP 603
Cdd:PRK12323 446 GAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDpppweelpPEFASPAPAQPDAAPAGWVAES 525

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 21704281  604 LQAPTLRGPEPARETPAklEPKPIIPKAEPRAKARKTEA 642
Cdd:PRK12323 526 IPDPATADPDDAFETLA--PAPAAAPAPRAAAATEPVVA 562
PHA03247 PHA03247
large tegument protein UL36; Provisional
 458-644 2.03e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.85  E-value: 2.03e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281   458 GAAGLPQPPRESPQLHERETPRPEGGSPSPAGTPPQPKRPRPGVSKDgllspgawngEPSGEgsrSVTP----------- 526
Cdd:PHA03247 2476 GAPVYRRPAEARFPFAAGAAPDPGGGGPPDPDAPPAPSRLAPAILPD----------EPVGE---PVHPrmltwirglee 2542

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281   527 --SEGAGRRSP-----ARPATERMAIEALQAPPAPSrEPEVAlyqgyhSYAVRTTPPEPPPFEDQPEPEvSGSESAPSSP 599
Cdd:PHA03247 2543 laSDDAGDPPPplppaAPPAAPDRSVPPPRPAPRPS-EPAVT------SRARRPDAPPQSARPRAPVDD-RGDPRGPAPP 2614

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 21704281   600 ATAPLQAPTLRGPEPARETPAKLEPKPIIPKAEPRAKARKTEARG 644
Cdd:PHA03247 2615 SPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPG 2659
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 451-635 2.61e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.12  E-value: 2.61e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281  451 EPPDRGAGAAGLPQPPRESPQLHERETPRPEGGSPSPAGTPPQPKRPRPGVSKDGLLSPGAWNGEPSGEGSRSvtPSEGA 530
Cdd:PRK07764 620 APAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAA--PAGAA 697

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281  531 GRRSPARPATERMAIEALQAPPAPSREPevalyQGYHSYAVRTTPPEPPPFEDQPEPEVSGSESAPSSPATAPLQAPTLR 610
Cdd:PRK07764 698 PAQPAPAPAATPPAGQADDPAAQPPQAA-----QGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAA 772

                        170       180
                 ....*....|....*....|....*
gi 21704281  611 GPEPARETPAKLEPKPIIPKAEPRA 635
Cdd:PRK07764 773 APPPSPPSEEEEMAEDDAPSMDDED 797
PHA03264 PHA03264
envelope glycoprotein D; Provisional
 478-558 2.99e-03

envelope glycoprotein D; Provisional


Pssm-ID: 223029 [Multi-domain]  Cd Length: 416  Bit Score: 40.76  E-value: 2.99e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281  478 PRPEGGSPSPAGTPPQPKRPRPGVSKDGllsPGAWNGEPSGEGSRSVTPSEGAG---RRSPARPATERMAIEALQAPPAP 554
Cdd:PHA03264 268 PAPSGGSPAPPGDDRPEAKPEPGPVEDG---APGRETGGEGEGPEPAGRDGAAGgepKPGPPRPAPDADRPEGWPSLEAI 344


                 ....
gi 21704281  555 SREP 558
Cdd:PHA03264 345 TFPP 348
PHA03381 PHA03381
tegument protein VP22; Provisional
 451-561 3.04e-03

tegument protein VP22; Provisional


Pssm-ID: 177618 [Multi-domain]  Cd Length: 290  Bit Score: 40.38  E-value: 3.04e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281  451 EPPDRG-AGAAGLPQPPRESPQLHERETPRPE----GGSPSPAGTPPQPKRPRPGVSKDGLLSPGAWNGEPSGEGSRsvt 525
Cdd:PHA03381  39 EPADRArRGAGQARGRSQAERRFHHYDEARADypyyTGSSSEDERPADPRPSRRPHAQPEASGPGPARGARGPAGSR--- 115

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 21704281  526 pseGAGRRSPARPAteRMAIEALQAPPAPSREPEVA 561
Cdd:PHA03381 116 ---GRGRRAESPSP--RDPPNPKGASAPRGRKSACA 146
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
104-125 3.79e-03

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 35.01  E-value: 3.79e-03
                           10        20
                   ....*....|....*....|..
gi 21704281    104 AKYEGTWNNGLQDGYGTETYAD 125
Cdd:smart00698   1 DRYEGEWRNGKRHGRGVYTYAN 22
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 452-558 4.12e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 40.54  E-value: 4.12e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281   452 PPDRGAGAAGLPQPPRESPQLHERETPRPEGGSPSPAGTPPQPKRPRPGVSKDGLLSPGAWNGEPSGEG-SRSVTPSEGA 530
Cdd:PHA03307   88 PTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGaSPAAVASDAA 167

                          90       100
                  ....*....|....*....|....*...
gi 21704281   531 GRRSPARPATerMAIEALQAPPAPSREP 558
Cdd:PHA03307  168 SSRQAALPLS--SPEETARAPSSPPAEP 193
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
456-644 4.90e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 40.22  E-value: 4.90e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281  456 GAGAAGLPQPPRESPQLHERETP-------RPEGGSPSPAGTPPQPKRPRPGVSKDGLLSPGAWNGEPSGEGSRSVTPSE 528
Cdd:PRK07003 367 APGGGVPARVAGAVPAPGARAAAavgasavPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRGDDAADGD 446

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281  529 GAGRRSPARPATERMAIEALQAPPAPSREPEVAlyqgyhsyAVRTTPPEPPPFEDQPEPEVSGSESAPSSPATAPLQAPT 608
Cdd:PRK07003 447 APVPAKANARASADSRCDERDAQPPADSGSASA--------PASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASR 518

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 21704281  609 LRGPEPARetpaklEPKPIIPKAEPRAKARKTEARG 644
Cdd:PRK07003 519 EDAPAAAA------PPAPEARPPTPAAAAPAARAGG 548
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 465-626 5.05e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 40.15  E-value: 5.05e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281   465 PPRESPQLHERETPRP-EGGSPSPAGTPPQPKRPRPGVSKDGLLSPGAWNGEPSGEgSRSVTPSEGAGRRSPARPATerm 543
Cdd:PHA03307  765 PAKLAEALALLEPAEPqRGAGSSPPVRAEAAFRRPGRLRRSGPAADAASRTASKRK-SRSHTPDGGSESSGPARPPG--- 840

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281   544 aieALQAPPAPSREPEVALYQGYHSYAVRTTPPEPPPFEDQPEPEVSGSESAPSSPATAPLQAPTLRGPEPARetpAKLE 623
Cdd:PHA03307  841 ---AAARPPPARSSESSKSKPAAAGGRARGKNGRRRPRPPEPRARPGAAAPPKAAAAAPPAGAPAPRPRPAPR---VKLG 914


                  ...
gi 21704281   624 PKP 626
Cdd:PHA03307  915 PMP 917
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 453-643 5.18e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 40.15  E-value: 5.18e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281   453 PDRGAGAA---GLPQPPRESPQLHERETPRPeggSPSPAGTPPQPKRPRPGVSKDGLLSPGAWNGEPSGEGSRSVTPSEG 529
Cdd:PHA03307  228 AADDAGASssdSSSSESSGCGWGPENECPLP---RPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPG 304

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281   530 AGRRSPARPATERMAIEALQAPPAPSREPEVAlyqgyHSYAVRTTPPEPPpfedqpepevSGSESAPSSPATAPlqaptl 609
Cdd:PHA03307  305 SGPAPSSPRASSSSSSSRESSSSSTSSSSESS-----RGAAVSPGPSPSR----------SPSPSRPPPPADPS------ 363

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 21704281   610 rgPEPARETPAKLEPKPIIPKAEP-RAKARKTEAR 643
Cdd:PHA03307  364 --SPRKRPRPSRAPSSPAASAGRPtRRRARAAVAG 396
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 463-637 8.52e-03

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 39.68  E-value: 8.52e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281   463 PQPPRESPQLHERETPRPEGG----SPSPAGTPPQPKRPRPGVS---------KDGLLSPGAWNGEPSGEGSRSVTPSEG 529
Cdd:PRK10263  349 VDVPPAQPTVAWQPVPGPQTGepviAPAPEGYPQQSQYAQPAVQyneplqqpvQPQQPYYAPAAEQPAQQPYYAPAPEQP 428

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21704281   530 AGRRSPARPATERMAIEALQAPPAPSREPEVALYQGYHSYaVRTTPPEPPPFEDQPEPEVSGSESAPSSPATAPLQAPTL 609
Cdd:PRK10263  429 AQQPYYAPAPEQPVAGNAWQAEEQQSTFAPQSTYQTEQTY-QQPAAQEPLYQQPQPVEQQPVVEPEPVVEETKPARPPLY 507

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 21704281   610 RGPE----PARE------------TPAKlEPKPIIPKAEPRAKA 637
Cdd:PRK10263  508 YFEEveekRAREreqlaawyqpipEPVK-EPEPIKSSLKAPSVA 550
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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