arrestin domain-containing protein 4 isoform 2 [Mus musculus]
arrestin family protein( domain architecture ID 10448464)
arrestin family protein with both N-terminal and C-terminal Ig-like beta-sandwich domains found in arrestin (S antigen); similar to Homo sapiens beta-arrestin-1 and arrestin domain-containing protein
List of domain hits
Name | Accession | Description | Interval | E-value | |||
Arrestin_N | pfam00339 | Arrestin (or S-antigen), N-terminal domain; Ig-like beta-sandwich fold. Scop reports ... |
19-166 | 1.31e-46 | |||
Arrestin (or S-antigen), N-terminal domain; Ig-like beta-sandwich fold. Scop reports duplication with C-terminal domain. : Pssm-ID: 425619 Cd Length: 148 Bit Score: 153.60 E-value: 1.31e-46
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Arrestin_C | smart01017 | Arrestin (or S-antigen), C-terminal domain; Ig-like beta-sandwich fold. Scop reports ... |
188-292 | 2.18e-27 | |||
Arrestin (or S-antigen), C-terminal domain; Ig-like beta-sandwich fold. Scop reports duplication with N-terminal domain. Arrestins comprise a family of closely-related proteins that includes beta-arrestin-1 and -2, which regulate the function of beta-adrenergic receptors by binding to their phosphorylated forms, impairing their capacity to activate G(S) proteins; Cone photoreceptors C-arrestin (arrestin-X). which could bind to phosphorylated red/green opsins; and Drosophila phosrestins I and II, which undergo light-induced phosphorylation, and probably play a role in photoreceptor transduction. : Pssm-ID: 214976 [Multi-domain] Cd Length: 142 Bit Score: 103.58 E-value: 2.18e-27
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Name | Accession | Description | Interval | E-value | ||||
Arrestin_N | pfam00339 | Arrestin (or S-antigen), N-terminal domain; Ig-like beta-sandwich fold. Scop reports ... |
19-166 | 1.31e-46 | ||||
Arrestin (or S-antigen), N-terminal domain; Ig-like beta-sandwich fold. Scop reports duplication with C-terminal domain. Pssm-ID: 425619 Cd Length: 148 Bit Score: 153.60 E-value: 1.31e-46
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Arrestin_C | smart01017 | Arrestin (or S-antigen), C-terminal domain; Ig-like beta-sandwich fold. Scop reports ... |
188-292 | 2.18e-27 | ||||
Arrestin (or S-antigen), C-terminal domain; Ig-like beta-sandwich fold. Scop reports duplication with N-terminal domain. Arrestins comprise a family of closely-related proteins that includes beta-arrestin-1 and -2, which regulate the function of beta-adrenergic receptors by binding to their phosphorylated forms, impairing their capacity to activate G(S) proteins; Cone photoreceptors C-arrestin (arrestin-X). which could bind to phosphorylated red/green opsins; and Drosophila phosrestins I and II, which undergo light-induced phosphorylation, and probably play a role in photoreceptor transduction. Pssm-ID: 214976 [Multi-domain] Cd Length: 142 Bit Score: 103.58 E-value: 2.18e-27
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Arrestin_C | pfam02752 | Arrestin (or S-antigen), C-terminal domain; Ig-like beta-sandwich fold. Scop reports ... |
188-293 | 1.00e-24 | ||||
Arrestin (or S-antigen), C-terminal domain; Ig-like beta-sandwich fold. Scop reports duplication with N-terminal domain. Pssm-ID: 460676 Cd Length: 135 Bit Score: 96.24 E-value: 1.00e-24
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ART10-like | cd22952 | Arrestin-related trafficking adapter 10 and similar proteins; Arrestin-related trafficking ... |
23-148 | 1.37e-05 | ||||
Arrestin-related trafficking adapter 10 and similar proteins; Arrestin-related trafficking adaptors (ARTs) function by targeting specific plasma membrane proteins to the endocytic system. They contain multiple PY motifs that are required for recruitment of Rsp5/Nedd4-like ubiquitin ligase which modifies the cargoes. It has been proposed that ARTs remodel the cell surface in response to environmental cues and may serve as part of a quality-control system at the plasma membrane, targeting damaged and misfolded membrane proteins for ubiquitination and subsequent degradation in the lysosome/vacuole. The specific target protein for ART10 is not yet known. Pssm-ID: 438568 [Multi-domain] Cd Length: 409 Bit Score: 46.20 E-value: 1.37e-05
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Name | Accession | Description | Interval | E-value | ||||
Arrestin_N | pfam00339 | Arrestin (or S-antigen), N-terminal domain; Ig-like beta-sandwich fold. Scop reports ... |
19-166 | 1.31e-46 | ||||
Arrestin (or S-antigen), N-terminal domain; Ig-like beta-sandwich fold. Scop reports duplication with C-terminal domain. Pssm-ID: 425619 Cd Length: 148 Bit Score: 153.60 E-value: 1.31e-46
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Arrestin_C | smart01017 | Arrestin (or S-antigen), C-terminal domain; Ig-like beta-sandwich fold. Scop reports ... |
188-292 | 2.18e-27 | ||||
Arrestin (or S-antigen), C-terminal domain; Ig-like beta-sandwich fold. Scop reports duplication with N-terminal domain. Arrestins comprise a family of closely-related proteins that includes beta-arrestin-1 and -2, which regulate the function of beta-adrenergic receptors by binding to their phosphorylated forms, impairing their capacity to activate G(S) proteins; Cone photoreceptors C-arrestin (arrestin-X). which could bind to phosphorylated red/green opsins; and Drosophila phosrestins I and II, which undergo light-induced phosphorylation, and probably play a role in photoreceptor transduction. Pssm-ID: 214976 [Multi-domain] Cd Length: 142 Bit Score: 103.58 E-value: 2.18e-27
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Arrestin_C | pfam02752 | Arrestin (or S-antigen), C-terminal domain; Ig-like beta-sandwich fold. Scop reports ... |
188-293 | 1.00e-24 | ||||
Arrestin (or S-antigen), C-terminal domain; Ig-like beta-sandwich fold. Scop reports duplication with N-terminal domain. Pssm-ID: 460676 Cd Length: 135 Bit Score: 96.24 E-value: 1.00e-24
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ART10-like | cd22952 | Arrestin-related trafficking adapter 10 and similar proteins; Arrestin-related trafficking ... |
23-148 | 1.37e-05 | ||||
Arrestin-related trafficking adapter 10 and similar proteins; Arrestin-related trafficking adaptors (ARTs) function by targeting specific plasma membrane proteins to the endocytic system. They contain multiple PY motifs that are required for recruitment of Rsp5/Nedd4-like ubiquitin ligase which modifies the cargoes. It has been proposed that ARTs remodel the cell surface in response to environmental cues and may serve as part of a quality-control system at the plasma membrane, targeting damaged and misfolded membrane proteins for ubiquitination and subsequent degradation in the lysosome/vacuole. The specific target protein for ART10 is not yet known. Pssm-ID: 438568 [Multi-domain] Cd Length: 409 Bit Score: 46.20 E-value: 1.37e-05
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Blast search parameters | ||||
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