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Conserved domains on  [gi|29893812|ref|NP_787109|]
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junctophilin-2 isoform 2 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PLN03185 super family cl33654
phosphatidylinositol phosphate kinase; Provisional
4-127 5.08e-16

phosphatidylinositol phosphate kinase; Provisional


The actual alignment was detected with superfamily member PLN03185:

Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 72.94  E-value: 5.08e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29893812    4 GRFDFDDGGAYCGGWEGGKAHGHGLCTGPKG---QGEYSGSWNFGFevaGVYTWPSGNTFEGYWSQGKRHGLGIET---- 76
Cdd:PLN03185  24 GKYLWSDGCMYEGEWRRGMRHGNGKISWPSGatyEGEFSGGYMHGS---GTYTGTDGTTYKGRWRLNLKHGLGYQRypng 100
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 29893812   77 ---KGRWL-----------------YKGEWTHGFKGRYGIrQSSSSGAKYEGTWNNGLQDGYGTETYADGG 127
Cdd:PLN03185 101 dvfEGSWIqglqegpgkytwangnvYLGDMKGGKMSGKGT-LTWVSGDSYEGQWLDGMMHGFGVYTWSDGG 170
 
Name Accession Description Interval E-value
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
4-127 5.08e-16

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 72.94  E-value: 5.08e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29893812    4 GRFDFDDGGAYCGGWEGGKAHGHGLCTGPKG---QGEYSGSWNFGFevaGVYTWPSGNTFEGYWSQGKRHGLGIET---- 76
Cdd:PLN03185  24 GKYLWSDGCMYEGEWRRGMRHGNGKISWPSGatyEGEFSGGYMHGS---GTYTGTDGTTYKGRWRLNLKHGLGYQRypng 100
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 29893812   77 ---KGRWL-----------------YKGEWTHGFKGRYGIrQSSSSGAKYEGTWNNGLQDGYGTETYADGG 127
Cdd:PLN03185 101 dvfEGSWIqglqegpgkytwangnvYLGDMKGGKMSGKGT-LTWVSGDSYEGQWLDGMMHGFGVYTWSDGG 170
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
2-126 3.96e-09

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 52.65  E-value: 3.96e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29893812   2 SGGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGqGEYSGSWNFG-FEVAGVYTWPSGNTFEGYWSQGKRHGLGIET-KGR 79
Cdd:COG4642 115 GGGVLEGDDGGGYGGGTADGGRGGGGIYTFPNG-DVYEGEFKNGkPHGQGTLTYADGDRYEGEFKNGKRHGQGTLTyANG 193
                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*..
gi 29893812  80 WLYKGEWTHGFKGRYGIRQsSSSGAKYEGTWNNGLQDGYGTETYADG 126
Cdd:COG4642 194 DVYEGEFKNGQRHGQGTYT-YADGDRYEGEFKNGKRHGQGTLTYADG 239
 
Name Accession Description Interval E-value
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
4-127 5.08e-16

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 72.94  E-value: 5.08e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29893812    4 GRFDFDDGGAYCGGWEGGKAHGHGLCTGPKG---QGEYSGSWNFGFevaGVYTWPSGNTFEGYWSQGKRHGLGIET---- 76
Cdd:PLN03185  24 GKYLWSDGCMYEGEWRRGMRHGNGKISWPSGatyEGEFSGGYMHGS---GTYTGTDGTTYKGRWRLNLKHGLGYQRypng 100
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 29893812   77 ---KGRWL-----------------YKGEWTHGFKGRYGIrQSSSSGAKYEGTWNNGLQDGYGTETYADGG 127
Cdd:PLN03185 101 dvfEGSWIqglqegpgkytwangnvYLGDMKGGKMSGKGT-LTWVSGDSYEGQWLDGMMHGFGVYTWSDGG 170
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
10-120 4.84e-13

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 64.47  E-value: 4.84e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29893812   10 DGGAYCGGWEGGKAHGHGLCTGPKGQgEYSGSWNFGF-EVAGVYTWPSGNTFEGYWSQGKRHGLGIETkgrWL----YKG 84
Cdd:PLN03185  76 DGTTYKGRWRLNLKHGLGYQRYPNGD-VFEGSWIQGLqEGPGKYTWANGNVYLGDMKGGKMSGKGTLT---WVsgdsYEG 151
                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 29893812   85 EWTHGFKGRYGIrQSSSSGAKYEGTWNNGLQDGYGT 120
Cdd:PLN03185 152 QWLDGMMHGFGV-YTWSDGGCYVGTWTRGLKDGKGV 186
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
38-126 2.05e-10

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 56.77  E-value: 2.05e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29893812   38 YSGSWNFGF-EVAGVYTWPSGNTFEGYWSQGKRHGLGietKGRW----LYKGEWT----HG-----------FKGRYGI- 96
Cdd:PLN03185  11 YSGSLLGNVpEGPGKYLWSDGCMYEGEWRRGMRHGNG---KISWpsgaTYEGEFSggymHGsgtytgtdgttYKGRWRLn 87
                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 29893812   97 ------RQSSSSGAKYEGTWNNGLQDGYGTETYADG 126
Cdd:PLN03185  88 lkhglgYQRYPNGDVFEGSWIQGLQEGPGKYTWANG 123
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
2-126 3.96e-09

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 52.65  E-value: 3.96e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29893812   2 SGGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGqGEYSGSWNFG-FEVAGVYTWPSGNTFEGYWSQGKRHGLGIET-KGR 79
Cdd:COG4642 115 GGGVLEGDDGGGYGGGTADGGRGGGGIYTFPNG-DVYEGEFKNGkPHGQGTLTYADGDRYEGEFKNGKRHGQGTLTyANG 193
                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*..
gi 29893812  80 WLYKGEWTHGFKGRYGIRQsSSSGAKYEGTWNNGLQDGYGTETYADG 126
Cdd:COG4642 194 DVYEGEFKNGQRHGQGTYT-YADGDRYEGEFKNGKRHGQGTLTYADG 239
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
3-126 7.30e-09

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 51.88  E-value: 7.30e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29893812   3 GGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGVYTWPSGNTFEGYWSQGKRHGLGIET-KGRWL 81
Cdd:COG4642  93 GGEGGFGGGGGGGGGKKGGGGGGGGVLEGDDGGGYGGGTADGGRGGGGIYTFPNGDVYEGEFKNGKPHGQGTLTyADGDR 172
                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*
gi 29893812  82 YKGEWTHGFKGRYGIRQsSSSGAKYEGTWNNGLQDGYGTETYADG 126
Cdd:COG4642 173 YEGEFKNGKRHGQGTLT-YANGDVYEGEFKNGQRHGQGTYTYADG 216
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
4-126 1.84e-08

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 51.11  E-value: 1.84e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29893812   4 GRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGqGEYSGSWNFG-FEVAGVYTWPSGNTFEGYWSQGKRHGLGIETkgrwly 82
Cdd:COG4642 163 GTLTYADGDRYEGEFKNGKRHGQGTLTYANG-DVYEGEFKNGqRHGQGTYTYADGDRYEGEFKNGKRHGQGTLT------ 235
                        90       100       110       120
                ....*....|....*....|....*....|....*....|....
gi 29893812  83 kgewthgfkgrygirqsSSSGAKYEGTWNNGLQDGYGTETYADG 126
Cdd:COG4642 236 -----------------YADGDRYEGEFKNGKRHGQGTMTYADG 262
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
4-74 9.15e-08

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 49.45  E-value: 9.15e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 29893812    4 GRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQgEYSGSWNFGFEVA-GVYTWPSGNTFEGYWSQGKRHGLGI 74
Cdd:PLN03185 116 GKYTWANGNVYLGDMKGGKMSGKGTLTWVSGD-SYEGQWLDGMMHGfGVYTWSDGGCYVGTWTRGLKDGKGV 186
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
1-127 5.88e-03

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 35.32  E-value: 5.88e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29893812   1 MSGGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGVYTWPSGNTFEGYWSQGKRHGLGIETKGRW 80
Cdd:COG4642  45 GYGGGADGGGGGGGGTGVAGGGGGEGGVTAAGGGGGGGGGKGDGGDGGGGEGGFGGGGGGGGGKKGGGGGGGGVLEGDDG 124
                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*..
gi 29893812  81 LYKGEWTHGFKGRYGIRQSSSSGAKYEGTWNNGLQDGYGTETYADGG 127
Cdd:COG4642 125 GGYGGGTADGGRGGGGIYTFPNGDVYEGEFKNGKPHGQGTLTYADGD 171
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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