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Conserved domains on  [gi|1720396819|ref|XP_030102792|]
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filensin isoform X2 [Mus musculus]

Protein Classification

AAA family ATPase( domain architecture ID 1003843)

AAA family ATPase containing an AAA (ATPases Associated with various cellular Activities) domain, may function as an ATP-dependent endonuclease or the ATPase component of an ABC-type transporter; similar to Bacillus subtilis protein YhaN

CATH:  3.40.50.300
Gene Ontology:  GO:0005524|GO:0016887
PubMed:  15037234|18208389|16828312|18466635|15037233

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YhaN super family cl34808
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
4-260 2.21e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


The actual alignment was detected with superfamily member COG4717:

Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 50.54  E-value: 2.21e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819   4 RLNKEADEALLRNLHLQLEAQFLQADISVAKDRYKKNLLEIQTYITVLQQIVQTAPQVSLVTGMREEKLFTEREVAALQN 83
Cdd:COG4717    67 ELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPE 146

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819  84 QLEEGR---EAVTHLQAQKAELQAQTTALEQAIKHAHECYD----EELQLYNEQIENLRKEIEEAERSLERSSYDCRQLA 156
Cdd:COG4717   147 RLEELEerlEELRELEEELEELEAELAELQEELEELLEQLSlateEELQDLAEELEELQQRLAELEEELEEAQEELEELE 226

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819 157 VAQQTLRNELDRYHRIIEIEgSRLSSVFIETPISLITPSHGAPLSLGSSVKDLARAVQDITA----------AKPRQKAL 226
Cdd:COG4717   227 EELEQLENELEAAALEERLK-EARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLAllflllarekASLGKEAE 305

                         250       260       270
                  ....*....|....*....|....*....|....
gi 1720396819 227 PKSLPKRKEIIAQDKVEETLEDAPLKPPQEPKAL 260
Cdd:COG4717   306 ELQALPALEELEEEELEELLAALGLPPDLSPEEL 339
 
Name Accession Description Interval E-value
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
4-260 2.21e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 50.54  E-value: 2.21e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819   4 RLNKEADEALLRNLHLQLEAQFLQADISVAKDRYKKNLLEIQTYITVLQQIVQTAPQVSLVTGMREEKLFTEREVAALQN 83
Cdd:COG4717    67 ELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPE 146

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819  84 QLEEGR---EAVTHLQAQKAELQAQTTALEQAIKHAHECYD----EELQLYNEQIENLRKEIEEAERSLERSSYDCRQLA 156
Cdd:COG4717   147 RLEELEerlEELRELEEELEELEAELAELQEELEELLEQLSlateEELQDLAEELEELQQRLAELEEELEEAQEELEELE 226

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819 157 VAQQTLRNELDRYHRIIEIEgSRLSSVFIETPISLITPSHGAPLSLGSSVKDLARAVQDITA----------AKPRQKAL 226
Cdd:COG4717   227 EELEQLENELEAAALEERLK-EARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLAllflllarekASLGKEAE 305

                         250       260       270
                  ....*....|....*....|....*....|....
gi 1720396819 227 PKSLPKRKEIIAQDKVEETLEDAPLKPPQEPKAL 260
Cdd:COG4717   306 ELQALPALEELEEEELEELLAALGLPPDLSPEEL 339
PRK09039 PRK09039
peptidoglycan -binding protein;
74-221 2.66e-05

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 46.50  E-value: 2.66e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819  74 TEREVAALQNQLEEGREAVTHLQAQKAELQAQTTALEQAIKHAhecyDEELQLYNEQIENLRKEIEEAERSLERSSYDCR 153
Cdd:PRK09039   93 AEAERSRLQALLAELAGAGAAAEGRAGELAQELDSEKQVSARA----LAQVELLNQQIAALRRQLAALEAALDASEKRDR 168

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819 154 Q-------------LAVAQQTlrNELDRYH-----RI---------IEIEGSRL---SSVFIETPISLITPSHGAplslg 203
Cdd:PRK09039  169 EsqakiadlgrrlnVALAQRV--QELNRYRseffgRLreilgdregIRIVGDRFvfqSEVLFPTGSAELNPEGQA----- 241

                         170
                  ....*....|....*...
gi 1720396819 204 sSVKDLARAVQDITAAKP 221
Cdd:PRK09039  242 -EIAKLAAALIELAKEIP 258
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2-168 3.81e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 46.59  E-value: 3.81e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819    2 LERLNKEADEALLRNLHL-QLEAQFLQADISVAKDRykKNLLEIQTYITVLQQIVQTapQVSLVTGMREEKLFTEREVAA 80
Cdd:TIGR02168  767 EERLEEAEEELAEAEAEIeELEAQIEQLKEELKALR--EALDELRAELTLLNEEAAN--LRERLESLERRIAATERRLED 842

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819   81 LQNQLEEGREAVTHLQAQKAELQAQTTALEQAIKHAHECYD---EELQLYNEQIENLRKEIEEAERSLERSSYDCRQLAV 157
Cdd:TIGR02168  843 LEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERAsleEALALLRSELEELSEELRELESKRSELRRELEELRE 922

                          170
                   ....*....|.
gi 1720396819  158 AQQTLRNELDR 168
Cdd:TIGR02168  923 KLAQLELRLEG 933
Filament pfam00038
Intermediate filament protein;
5-179 1.28e-04

Intermediate filament protein;


Pssm-ID: 459643 [Multi-domain]  Cd Length: 313  Bit Score: 44.14  E-value: 1.28e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819   5 LNKEADEALLRNLHLQLEAQFLQADISVAKDRYKKNLLEIQTYITVLQQIVQ--TAPQVSLVTGMRE------------- 69
Cdd:pfam00038 108 LRKDLDEATLARVDLEAKIESLKEELAFLKKNHEEEVRELQAQVSDTQVNVEmdAARKLDLTSALAEiraqyeeiaaknr 187

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819  70 ---EKLFTER-------------EVAALQNQLEEGREAVTHLQAQKAELQAQTTALEQAIKHAHECYDEELQLYNEQIEN 133
Cdd:pfam00038 188 eeaEEWYQSKleelqqaaarngdALRSAKEEITELRRTIQSLEIELQSLKKQKASLERQLAETEERYELQLADYQELISE 267

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1720396819 134 LRKEIEEAERSLERSSYDCRQLAVAQQTLRNELDRYHRIIEIEGSR 179
Cdd:pfam00038 268 LEAELQETRQEMARQLREYQELLNVKLALDIEIATYRKLLEGEECR 313
ClyA_Cry6Aa-like cd22656
Bacillus thuringiensis crystal 6Aa (Cry6Aa) toxin, and similar proteins; This model includes ...
 2-147 9.47e-03

Bacillus thuringiensis crystal 6Aa (Cry6Aa) toxin, and similar proteins; This model includes pesticidal Cry6Aa toxin from Bacillus thuringiensis, one of the many parasporal crystal (Cry) toxins produced during the sporulation phase of growth. Many of these proteins are toxic to numerous insect species and have been effectively used as proteinaceous insecticides to directly kill insect pests; some have been used to control insect growth on transgenic agricultural plants. Cry6Aa exists as a protoxin, which is activated by cleavage using trypsin. Structure studies for Cry6Aa support a mechanism of action by pore formation, similar to cytolysin A (ClyA)-type alpha pore-forming toxins (alpha-PFTs) such as HblB, and bioassay and mutation studies show that Cry6Aa is an active pore-forming toxin. Cry6Aa shows atypical features compared to other members of alpha-PFTs, including internal repeat sequences and small loop regions within major alpha helices.


Pssm-ID: 439154 [Multi-domain]  Cd Length: 309  Bit Score: 38.12  E-value: 9.47e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819   2 LERLNKEADEallrnlhLQLEAQFLQADISVAKDRYKKNLLEIQTYITVLQQIVQTapqvslvtgmrEEKLFTEREVAAL 81
Cdd:cd22656   123 LDDLLKEAKK-------YQDKAAKVVDKLTDFENQTEKDQTALETLEKALKDLLTD-----------EGGAIARKEIKDL 184

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1720396819  82 QNQLEEGR-EAVTHLQAQKAELQAQTTALEQAIKHAHECYDEeLQLYNEQIENLRKEIEEAERSLER 147
Cdd:cd22656   185 QKELEKLNeEYAAKLKAKIDELKALIADDEAKLAAALRLIAD-LTAADTDLDNLLALIGPAIPALEK 250
 
Name Accession Description Interval E-value
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
4-260 2.21e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 50.54  E-value: 2.21e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819   4 RLNKEADEALLRNLHLQLEAQFLQADISVAKDRYKKNLLEIQTYITVLQQIVQTAPQVSLVTGMREEKLFTEREVAALQN 83
Cdd:COG4717    67 ELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPE 146

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819  84 QLEEGR---EAVTHLQAQKAELQAQTTALEQAIKHAHECYD----EELQLYNEQIENLRKEIEEAERSLERSSYDCRQLA 156
Cdd:COG4717   147 RLEELEerlEELRELEEELEELEAELAELQEELEELLEQLSlateEELQDLAEELEELQQRLAELEEELEEAQEELEELE 226

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819 157 VAQQTLRNELDRYHRIIEIEgSRLSSVFIETPISLITPSHGAPLSLGSSVKDLARAVQDITA----------AKPRQKAL 226
Cdd:COG4717   227 EELEQLENELEAAALEERLK-EARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLAllflllarekASLGKEAE 305

                         250       260       270
                  ....*....|....*....|....*....|....
gi 1720396819 227 PKSLPKRKEIIAQDKVEETLEDAPLKPPQEPKAL 260
Cdd:COG4717   306 ELQALPALEELEEEELEELLAALGLPPDLSPEEL 339
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 74-267 4.34e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.99  E-value: 4.34e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819  74 TEREVAALQNQLEEGREAVTHLQAQKAELQAQTTALEQAIKHAHecydEELQLYNEQIENLRKEIEEAERSLERSSydcR 153
Cdd:COG4942    25 AEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALA----RRIRALEQELAALEAELAELEKEIAELR---A 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819 154 QLAVAQQTLRNELDRYHRIIEIEGSRL---SSVFIETPISLITPSHGAP------LSLGSSVKDLARAVQDITAAKPRQK 224
Cdd:COG4942    98 ELEAQKEELAELLRALYRLGRQPPLALllsPEDFLDAVRRLQYLKYLAParreqaEELRADLAELAALRAELEAERAELE 177

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1720396819 225 ALPKSLPKRKEIIAQDKVE--ETLEDAPLKPPQEPKALQVERKAE 267
Cdd:COG4942   178 ALLAELEEERAALEALKAErqKLLARLEKELAELAAELAELQQEA 222
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 7-168 9.13e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 48.78  E-value: 9.13e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819   7 KEADEALLRNLHLQLEAQFLQADISVAKDRYKKNLLEIQTYITVLQQIVQTAPQVSL-VTGMREEKLFTEREVAALQNQL 85
Cdd:COG1196   225 LEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELeLEEAQAEEYELLAELARLEQDI 304

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819  86 EEGREAVTHLQAQKAELQAQTTALEQAIKHAhecyDEELQLYNEQIENLRKEIEEAERSLERSSydcRQLAVAQQTLRNE 165
Cdd:COG1196   305 ARLEERRRELEERLEELEEELAELEEELEEL----EEELEELEEELEEAEEELEEAEAELAEAE---EALLEAEAELAEA 377


                  ...
gi 1720396819 166 LDR 168
Cdd:COG1196   378 EEE 380
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
20-194 1.29e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 48.09  E-value: 1.29e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819  20 QLEAQF--LQADISVAKDRYKknllEIQTYITVLQQIVQTAPQVSLVTGMREEKLFTEREVAALQNQLEEGREAVTHLQA 97
Cdd:COG3206   223 ELESQLaeARAELAEAEARLA----ALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRA 298

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819  98 QKAELQAQttaLEQAIKHAHECYDEELQLYNEQIENLRKEIEEAERSLERSSydcrQLAVAQQTLRNELDRYHRIIE--- 174
Cdd:COG3206   299 QIAALRAQ---LQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELP----ELEAELRRLEREVEVARELYEsll 371

                         170       180
                  ....*....|....*....|..
gi 1720396819 175 --IEGSRLSSVFIETPISLITP 194
Cdd:COG3206   372 qrLEEARLAEALTVGNVRVIDP 393
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2-159 1.43e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.99  E-value: 1.43e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819    2 LERLNKEADEallrnlhLQLEAQFLQADISVAKDRYKknllEIQTYITVLQQIVQTAPQVSLVTGmreeklfTEREVAAL 81
Cdd:COG4913    612 LAALEAELAE-------LEEELAEAEERLEALEAELD----ALQERREALQRLAEYSWDEIDVAS-------AEREIAEL 673

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819   82 QNQLEEGREA---VTHLQAQKAELQAQTTALEQAIKhahECYDEELQLyNEQIENLRKEIEEAERSLERSSYDCRQLAVA 158
Cdd:COG4913    674 EAELERLDASsddLAALEEQLEELEAELEELEEELD---ELKGEIGRL-EKELEQAEEELDELQDRLEAAEDLARLELRA 749


                   .
gi 1720396819  159 Q 159
Cdd:COG4913    750 L 750
PRK09039 PRK09039
peptidoglycan -binding protein;
74-221 2.66e-05

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 46.50  E-value: 2.66e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819  74 TEREVAALQNQLEEGREAVTHLQAQKAELQAQTTALEQAIKHAhecyDEELQLYNEQIENLRKEIEEAERSLERSSYDCR 153
Cdd:PRK09039   93 AEAERSRLQALLAELAGAGAAAEGRAGELAQELDSEKQVSARA----LAQVELLNQQIAALRRQLAALEAALDASEKRDR 168

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819 154 Q-------------LAVAQQTlrNELDRYH-----RI---------IEIEGSRL---SSVFIETPISLITPSHGAplslg 203
Cdd:PRK09039  169 EsqakiadlgrrlnVALAQRV--QELNRYRseffgRLreilgdregIRIVGDRFvfqSEVLFPTGSAELNPEGQA----- 241

                         170
                  ....*....|....*...
gi 1720396819 204 sSVKDLARAVQDITAAKP 221
Cdd:PRK09039  242 -EIAKLAAALIELAKEIP 258
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2-168 3.81e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 46.59  E-value: 3.81e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819    2 LERLNKEADEALLRNLHL-QLEAQFLQADISVAKDRykKNLLEIQTYITVLQQIVQTapQVSLVTGMREEKLFTEREVAA 80
Cdd:TIGR02168  767 EERLEEAEEELAEAEAEIeELEAQIEQLKEELKALR--EALDELRAELTLLNEEAAN--LRERLESLERRIAATERRLED 842

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819   81 LQNQLEEGREAVTHLQAQKAELQAQTTALEQAIKHAHECYD---EELQLYNEQIENLRKEIEEAERSLERSSYDCRQLAV 157
Cdd:TIGR02168  843 LEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERAsleEALALLRSELEELSEELRELESKRSELRRELEELRE 922

                          170
                   ....*....|.
gi 1720396819  158 AQQTLRNELDR 168
Cdd:TIGR02168  923 KLAQLELRLEG 933
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
18-174 6.36e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.06  E-value: 6.36e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819   18 HLQLEAQFLQADISVAKDRYKKnlleiqtyitvLQQIVQTAPQVSLVTGMREEKLFTEREVAALQNQLEEgreavthLQA 97
Cdd:COG4913    614 ALEAELAELEEELAEAEERLEA-----------LEAELDALQERREALQRLAEYSWDEIDVASAEREIAE-------LEA 675

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1720396819   98 QKAELQAQTTALEQAikhahecydeelqlyNEQIENLRKEIEEAERSLERSSYDCRQLAVAQQTLRNELDRYHRIIE 174
Cdd:COG4913    676 ELERLDASSDDLAAL---------------EEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLE 737
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
74-179 7.41e-05

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 45.62  E-value: 7.41e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819  74 TEREVAALQNQLEEGREAVTHLQAQKAELQAQTTALEQAIKHAHECY------DEELQLYNEQIENLRKEIEEAERSLER 147
Cdd:COG2433   411 EEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLERELSEARSEErreirkDREISRLDREIERLERELEEERERIEE 490

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1720396819 148 ssydcrqlavaqqtLRNELDRYHRIIEIEGSR 179
Cdd:COG2433   491 --------------LKRKLERLKELWKLEHSG 508
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2-174 8.22e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 45.70  E-value: 8.22e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819   2 LERLNKEADEALLRNLHLQLEAQFLQADISVAKDRYKKNLLEIQTYITVLQQIVQTAPQvslvtgmreeklfTEREVAAL 81
Cdd:COG1196   241 LEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELAR-------------LEQDIARL 307

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819  82 QNQLEEGREAVTHLQAQKAELQAQTTALEQAIKHAhecyDEELQLYNEQIENLRKEIEEAERSLERSSydcRQLAVAQQT 161
Cdd:COG1196   308 EERRRELEERLEELEEELAELEEELEELEEELEEL----EEELEEAEEELEEAEAELAEAEEALLEAE---AELAEAEEE 380

                         170
                  ....*....|...
gi 1720396819 162 LRNELDRYHRIIE 174
Cdd:COG1196   381 LEELAEELLEALR 393
Filament pfam00038
Intermediate filament protein;
5-179 1.28e-04

Intermediate filament protein;


Pssm-ID: 459643 [Multi-domain]  Cd Length: 313  Bit Score: 44.14  E-value: 1.28e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819   5 LNKEADEALLRNLHLQLEAQFLQADISVAKDRYKKNLLEIQTYITVLQQIVQ--TAPQVSLVTGMRE------------- 69
Cdd:pfam00038 108 LRKDLDEATLARVDLEAKIESLKEELAFLKKNHEEEVRELQAQVSDTQVNVEmdAARKLDLTSALAEiraqyeeiaaknr 187

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819  70 ---EKLFTER-------------EVAALQNQLEEGREAVTHLQAQKAELQAQTTALEQAIKHAHECYDEELQLYNEQIEN 133
Cdd:pfam00038 188 eeaEEWYQSKleelqqaaarngdALRSAKEEITELRRTIQSLEIELQSLKKQKASLERQLAETEERYELQLADYQELISE 267

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1720396819 134 LRKEIEEAERSLERSSYDCRQLAVAQQTLRNELDRYHRIIEIEGSR 179
Cdd:pfam00038 268 LEAELQETRQEMARQLREYQELLNVKLALDIEIATYRKLLEGEECR 313
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2-174 1.41e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 44.66  E-value: 1.41e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819    2 LERLNKEADEAL-LRNLHLQLEAqfLQADISVAK-DRYKKNLLEIQTYITVLQQIVQTApqvslvtgmreeklftEREVA 79
Cdd:TIGR02168  202 LKSLERQAEKAErYKELKAELRE--LELALLVLRlEELREELEELQEELKEAEEELEEL----------------TAELQ 263

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819   80 ALQNQLEEGREAVTHLQAQKAELQ-------AQTTALEQAIKHAHE---CYDEELQLYNEQIENLRKEIEEAERSLERSS 149
Cdd:TIGR02168  264 ELEEKLEELRLEVSELEEEIEELQkelyalaNEISRLEQQKQILRErlaNLERQLEELEAQLEELESKLDELAEELAELE 343

                          170       180
                   ....*....|....*....|....*
gi 1720396819  150 YDCRQLAVAQQTLRNELDRYHRIIE 174
Cdd:TIGR02168  344 EKLEELKEELESLEAELEELEAELE 368
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 2-146 1.75e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 42.99  E-value: 1.75e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819   2 LERLNKEAD--EALLRNLHLQLEAqfLQADISVAKDRYKKNLLEIQTyitVLQQIVQTAPQVSLVTGMRE------EKLF 73
Cdd:COG1579    26 LKELPAELAelEDELAALEARLEA--AKTELEDLEKEIKRLELEIEE---VEARIKKYEEQLGNVRNNKEyealqkEIES 100

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1720396819  74 TEREVAALQNQLEEGREAVTHLQAQKAELQAQTTALEQAIKHAHECYDEELQLYNEQIENLRKEIEEAERSLE 146
Cdd:COG1579   101 LKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKIP 173
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2-168 4.09e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 43.12  E-value: 4.09e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819    2 LERLNKEADEALLRNLHLQLEAQFLQADISVAKDRykknLLEIQTYITVLQQIVQTApqVSLVTGMREEKLFTEREVAAL 81
Cdd:TIGR02168  241 LEELQEELKEAEEELEELTAELQELEEKLEELRLE----VSELEEEIEELQKELYAL--ANEISRLEQQKQILRERLANL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819   82 QNQLEEGREAVTHLQAQKAELQAQTTALEQAIKHAHECYDEELQLYNE-------------------------------Q 130
Cdd:TIGR02168  315 ERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEEleaeleelesrleeleeqletlrskvaqlelQ 394

                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 1720396819  131 IENLRKEIEEAERSLERSSYDCRQLAVAQQTLRNELDR 168
Cdd:TIGR02168  395 IASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEE 432
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
2-171 4.38e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.83  E-value: 4.38e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819   2 LERLNKEADEALLRNLHLQLEAQFLQADISVAKDRYKKNLLEIQTYITVLQQIVQTAPQVSLVTGMRE-EKLFTE----- 75
Cdd:COG4717   304 AEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEiAALLAEagved 383

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819  76 ----REVAALQNQLEEGREAVTHLQAQ-----KAELQAQTTALEQAIKHAHECYDEELQLYNEQIENLRKEIEEAERSLE 146
Cdd:COG4717   384 eeelRAALEQAEEYQELKEELEELEEQleellGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELE 463

                         170       180
                  ....*....|....*....|....*..
gi 1720396819 147 R--SSYDCRQLAVAQQTLRNELDRYHR 171
Cdd:COG4717   464 QleEDGELAELLQELEELKAELRELAE 490
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
75-174 8.75e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.21  E-value: 8.75e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819   75 EREVAALQNQLEEGREAVTHLQAQKAELQAQTTALEQaIKHAHecydEELQLYNEQIEN---LRKEIEEAE---RSLERS 148
Cdd:COG4913    609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQE-RREAL----QRLAEYSWDEIDvasAEREIAELEaelERLDAS 683

                           90       100
                   ....*....|....*....|....*.
gi 1720396819  149 SYDCRQLAVAQQTLRNELDRYHRIIE 174
Cdd:COG4913    684 SDDLAALEEQLEELEAELEELEEELD 709
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
24-180 8.90e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.93  E-value: 8.90e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819  24 QFLQADISVAKDRYKKNLLEIQTYITVLQQIVQTApQVSLVTGMREEKLF-TEREVAALQNQLEEGREAVTHLQAQKAEL 102
Cdd:COG3206   160 AYLEQNLELRREEARKALEFLEEQLPELRKELEEA-EAALEEFRQKNGLVdLSEEAKLLLQQLSELESQLAEARAELAEA 238

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819 103 QAQTTALEQAIKHAHECYDEELQlyNEQIENLRKEIEEAERSL--ERSSYDCRQLAVaqQTLRNELDRYHRIIEIEGSRL 180
Cdd:COG3206   239 EARLAALRAQLGSGPDALPELLQ--SPVIQQLRAQLAELEAELaeLSARYTPNHPDV--IALRAQIAALRAQLQQEAQRI 314
EmrA COG1566
Multidrug resistance efflux pump EmrA [Defense mechanisms];
15-148 1.14e-03

Multidrug resistance efflux pump EmrA [Defense mechanisms];


Pssm-ID: 441174 [Multi-domain]  Cd Length: 331  Bit Score: 41.19  E-value: 1.14e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819  15 RNLHLQLEAqfLQADISVAKDRYK--KNLLEIQTYITVLQQIVQTApQVSLVTGMRE----EKLFTEREVAalQNQLEEG 88
Cdd:COG1566    79 TDLQAALAQ--AEAQLAAAEAQLArlEAELGAEAEIAAAEAQLAAA-QAQLDLAQREleryQALYKKGAVS--QQELDEA 153

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819  89 REAVTHLQAQKAELQAQTTALEQAIKhahecYDEELQLYNEQIENLRKEIEEAERSLERS 148
Cdd:COG1566   154 RAALDAAQAQLEAAQAQLAQAQAGLR-----EEEELAAAQAQVAQAEAALAQAELNLART 208
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1-171 1.33e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.44  E-value: 1.33e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819    1 MLER--LNKEADEAL-----LRNLHLQLEAQFLQAD----ISVAKDRYKKNLLEIQtyitVLQQIVQTAPQvslvtgmre 69
Cdd:COG4913    217 MLEEpdTFEAADALVehfddLERAHEALEDAREQIEllepIRELAERYAAARERLA----ELEYLRAALRL--------- 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819   70 ekLFTEREVAALQNQLEEGREAVTHLQAQKAELQAQTTALEQaikhahecydEELQLYNEQIENLRKEIEEAERSLERss 149
Cdd:COG4913    284 --WFAQRRLELLEAELEELRAELARLEAELERLEARLDALRE----------ELDELEAQIRGNGGDRLEQLEREIER-- 349

                          170       180
                   ....*....|....*....|..
gi 1720396819  150 ydcrqLAVAQQTLRNELDRYHR 171
Cdd:COG4913    350 -----LERELEERERRRARLEA 366
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
13-155 1.40e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 41.29  E-value: 1.40e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819  13 LLRNLHLQLEAQFLQADISVAKDRYKKNLLEIQTYITVLQQIVQTAPQVSLVTGMREEKLFTEREVAALQNQLEEGREAV 92
Cdd:COG4717    39 LLAFIRAMLLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREEL 118

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1720396819  93 THLQAQKA--ELQAQTTALEQAIKHAHECYdEELQLYNEQIENLRKEIEEAERSLERSSYDCRQL 155
Cdd:COG4717   119 EKLEKLLQllPLYQELEALEAELAELPERL-EELEERLEELRELEEELEELEAELAELQEELEEL 182
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 76-174 1.98e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 41.08  E-value: 1.98e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819  76 REVAALQNQLEEGREAVTHLQAQKAELQAQTTALEQAIKHAhecyDEELQLYNEQIENLRKEIEEAERSLERSSYDCRQL 155
Cdd:COG1196   232 LKLRELEAELEELEAELEELEAELEELEAELAELEAELEEL----RLELEELELELEEAQAEEYELLAELARLEQDIARL 307

                          90
                  ....*....|....*....
gi 1720396819 156 AVAQQTLRNELDRYHRIIE 174
Cdd:COG1196   308 EERRRELEERLEELEEELA 326
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 2-147 3.16e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 40.39  E-value: 3.16e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819   2 LERLNKEADEALLRNLHLQLEAQflqadisvakdryKKNLLEIQTYITVLQQIVQTAPQVslVTGMREEKLFTEREVAAL 81
Cdd:TIGR04523 297 ISDLNNQKEQDWNKELKSELKNQ-------------EKKLEEIQNQISQNNKIISQLNEQ--ISQLKKELTNSESENSEK 361

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1720396819  82 QNQLEEGREAVTHLQAQKAE-------LQAQTTALEQAIKHahecYDEELQLYNEQIENLRKEIEEAERSLER 147
Cdd:TIGR04523 362 QRELEEKQNEIEKLKKENQSykqeiknLESQINDLESKIQN----QEKLNQQKDEQIKKLQQEKELLEKEIER 430
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
5-160 3.45e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 39.89  E-value: 3.45e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819   5 LNKEADEALLRNLHLQLEAQFLQADISVAKDRYKKNLLEIQTYITVLQQIVQTAPQVSL-VTGMREEKLFTEREVAALQN 83
Cdd:COG4372    29 LSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEqLQAAQAELAQAQEELESLQE 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819  84 QLEEGREAVTHLQAQKAELQAQTTALEQAIKHAHECY---DEELQLYNEQIENLRKEIEEAERSLERSSYDCRQLAVAQQ 160
Cdd:COG4372   109 EAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIaerEEELKELEEQLESLQEELAALEQELQALSEAEAEQALDEL 188
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 72-180 4.08e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 40.04  E-value: 4.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819   72 LFTEREVAALQNQLEEGREAVTHLQAQKAELQAQTTALEQAIKHAhecyDEELQLYNEQIENLRKEIEEAERSLERSSYD 151
Cdd:TIGR02168  673 LERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQL----RKELEELSRQISALRKDLARLEAEVEQLEER 748

                           90       100
                   ....*....|....*....|....*....
gi 1720396819  152 CRQLAVAQQTLRNELDRYHRIIEIEGSRL 180
Cdd:TIGR02168  749 IAQLSKELTELEAEIEELEERLEEAEEEL 777
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 76-164 4.70e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 39.94  E-value: 4.70e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819   76 REVAALQNQLEEGREAVTHLQAQKAELQAQTTALEQAIKHAHECYDEELQlynEQIENLRKEIE---EAERSLERSSYDC 152
Cdd:COG3096    843 QRRSELERELAQHRAQEQQLRQQLDQLKEQLQLLNKLLPQANLLADETLA---DRLEELREELDaaqEAQAFIQQHGKAL 919

                           90
                   ....*....|..
gi 1720396819  153 RQLAVAQQTLRN 164
Cdd:COG3096    920 AQLEPLVAVLQS 931
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 75-161 4.99e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 39.43  E-value: 4.99e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819  75 EREVAALQNQLEEGREAVTHLQAQKAELQAQTTALEQAIKHAhecyDEELQLYNEQIENLRKEIEEAERSLERSSYDCRQ 154
Cdd:COG3883    15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNEL----QAELEALQAEIDKLQAEIAEAEAEIEERREELGE 90


                  ....*..
gi 1720396819 155 LAVAQQT 161
Cdd:COG3883    91 RARALYR 97
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 2-140 5.44e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 38.75  E-value: 5.44e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819   2 LERLNKEADEALLRNLHLQLEAQFLQADISVAK---DRYKKNLLEIQTY--ITVLQQIVQTApqvslvtgmREEKLFTER 76
Cdd:COG1579    40 LAALEARLEAAKTELEDLEKEIKRLELEIEEVEariKKYEEQLGNVRNNkeYEALQKEIESL---------KRRISDLED 110

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1720396819  77 EVAALQNQLEEGREAVTHLQAQKAELQAQTTALEQAIKHAHECYDEELQLYNEQIENLRKEIEE 140
Cdd:COG1579   111 EILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKIPP 174
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
75-171 7.44e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 39.13  E-value: 7.44e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819   75 EREVAALQNQLEEGREAVTHLQAQKAELQAQTTALEQAIKHAHECYDE-------------ELQLYNEQIENLRKEIEEA 141
Cdd:COG4913    691 EEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAaedlarlelrallEERFAAALGDAVERELREN 770

                           90       100       110
                   ....*....|....*....|....*....|.
gi 1720396819  142 -ERSLERSSydcRQLAVAQQTLRNELDRYHR 171
Cdd:COG4913    771 lEERIDALR---ARLNRAEEELERAMRAFNR 798
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2-141 8.38e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 39.13  E-value: 8.38e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819    2 LERLNKEADEA--LLRNLHLQLEA------QFLQADISVAKDRYKKNLLEIQTYITVLQQIVQTAPQ-----VSLVTGMR 68
Cdd:COG4913    311 LERLEARLDALreELDELEAQIRGnggdrlEQLEREIERLERELEERERRRARLEALLAALGLPLPAsaeefAALRAEAA 390

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1720396819   69 EEKLFTEREVAALQNQLEEGREAVTHLQAQKAELQAQTTALEQAIKhaheCYDEELQlyneqieNLRKEIEEA 141
Cdd:COG4913    391 ALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKS----NIPARLL-------ALRDALAEA 452
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 70-174 9.43e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 38.90  E-value: 9.43e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819   70 EKLFTEREVAALQNQLEEGREAVTHLQAQKAELQAQTTALEQAIKHAHE----CYDEELQLYNEQIENLRKEIEEAERSL 145
Cdd:TIGR02169  231 EKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKkikdLGEEEQLRVKEKIGELEAEIASLERSI 310

                           90       100
                   ....*....|....*....|....*....
gi 1720396819  146 ERSSYDCRQLAVAQQTLRNELDRYHRIIE 174
Cdd:TIGR02169  311 AEKERELEDAEERLAKLEAEIDKLLAEIE 339
ClyA_Cry6Aa-like cd22656
Bacillus thuringiensis crystal 6Aa (Cry6Aa) toxin, and similar proteins; This model includes ...
 2-147 9.47e-03

Bacillus thuringiensis crystal 6Aa (Cry6Aa) toxin, and similar proteins; This model includes pesticidal Cry6Aa toxin from Bacillus thuringiensis, one of the many parasporal crystal (Cry) toxins produced during the sporulation phase of growth. Many of these proteins are toxic to numerous insect species and have been effectively used as proteinaceous insecticides to directly kill insect pests; some have been used to control insect growth on transgenic agricultural plants. Cry6Aa exists as a protoxin, which is activated by cleavage using trypsin. Structure studies for Cry6Aa support a mechanism of action by pore formation, similar to cytolysin A (ClyA)-type alpha pore-forming toxins (alpha-PFTs) such as HblB, and bioassay and mutation studies show that Cry6Aa is an active pore-forming toxin. Cry6Aa shows atypical features compared to other members of alpha-PFTs, including internal repeat sequences and small loop regions within major alpha helices.


Pssm-ID: 439154 [Multi-domain]  Cd Length: 309  Bit Score: 38.12  E-value: 9.47e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819   2 LERLNKEADEallrnlhLQLEAQFLQADISVAKDRYKKNLLEIQTYITVLQQIVQTapqvslvtgmrEEKLFTEREVAAL 81
Cdd:cd22656   123 LDDLLKEAKK-------YQDKAAKVVDKLTDFENQTEKDQTALETLEKALKDLLTD-----------EGGAIARKEIKDL 184

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1720396819  82 QNQLEEGR-EAVTHLQAQKAELQAQTTALEQAIKHAHECYDEeLQLYNEQIENLRKEIEEAERSLER 147
Cdd:cd22656   185 QKELEKLNeEYAAKLKAKIDELKALIADDEAKLAAALRLIAD-LTAADTDLDNLLALIGPAIPALEK 250
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1-174 9.95e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 38.74  E-value: 9.95e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819    1 MLERLNKEADE---ALLRNL--HLQLEAQFLQADISVAKDRYKknllEIQTYITVLQQIVQTAPQvslvtgmreeklfte 75
Cdd:COG4913    277 LRAALRLWFAQrrlELLEAEleELRAELARLEAELERLEARLD----ALREELDELEAQIRGNGG--------------- 337

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720396819   76 REVAALQNQLEegreavtHLQAQKAELQAQTTALEQAIKHAHECYDEELQLYNEQIENLRKEIEEAERSLERSSYDCRQL 155
Cdd:COG4913    338 DRLEQLEREIE-------RLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEA 410

                          170
                   ....*....|....*....
gi 1720396819  156 AVAQQTLRNELDRYHRIIE 174
Cdd:COG4913    411 EAALRDLRRELRELEAEIA 429
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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