Conserved Protein Domain Family
Calc_CGRP_IAPP

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pfam00214: Calc_CGRP_IAPP (this model, PSSM-Id:395159 is obsolete and has been replaced by 459715)
Calcitonin / CGRP / IAPP family
Statistics
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PSSM-Id: 395159
Aligned: 59 rows
Threshold Bit Score: 53.5034
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_003773643   1 MQLV-PVALIY-LGSFAFLGADTARLDLASE---------FRKKWNKWALSRGKRE--LRVPSNPlaGLAEVKTGPvqtf 67  Tasmanian devil
XP_003220825   1 MCSLkGPFLFi-FLSVTFNSLEATPVERLLSladd--lsdGTPDRQEWFLPILSRStgFLGINGAllGEEAPKAI----- 72  green anole
Q90743         1 MCNLkLSAFFi-VLSVTLNCLEATSIEKLLSvtdd--lsdGTSKRQEWILPIMSQNt-LSGLSEEmpEQPAAKTK----- 71  chicken
XP_005998925   1 MCCLkLPIVLv-VLSGALNCLQAAPTNRFLAlatgsdqanGPSPRRGWIFPVLSNNt-LLGFTSSipGEDIAKMK----- 73  coelacanth
XP_015207527   1 MCNLkLPAFVl-VLSVVIQWVSAAPSNRYSPvyte--qsdAWPERERWLLPGFSKNs-FLSFTGVlpEGDPPKRI----- 71  spotted gar
XP_007235079   1 MYHLkVPVLLl-LLLVLLQCVTTAPNYRYSSss-----aeRPGEAEGWMAPGLSLTp-FLEFAGSrpQRGLSALN----- 68  Mexican tetra
6_pfamImport   1 MYHLrLPVLLl-MLLVVLRCVTAAPGHRYFTpsssseresGLPDTDGWLAPGLISNa-FFGLVGTrpERGLTDMN----- 73 
4_pfamImport   1 -----------sIMEVAVLLLLTIPMRTATP---------VRQT------HRTQTE-----------SLSLEKSVQrsrd 43 
XP_003455427   1 MRLFlHTIICCcVFTTVLPLVKGARGETNTS---------LRKRSRVWLQSHMKRD--LR---------SRLVTGDdqyf 60  Nile tilapia
NP_001313638   1 MQLIlQSIFCCcLLAAVAPGVDSAKHD-------------LKR--SVWL-QRSKRD--L--------SLPALRALEnrqf 54  zebrafish
XP_003773643  68 irtqd------vkgasrspQPsspDAARIRvkryrqsmnsfphfqslrIGCRFGTCTLQNLAHQIYQF-TDKDKDDSAPP 140 Tasmanian devil
XP_003220825  73 --------------------K---SHRLEK------------------RRCNTATCVTQRLADFLVRS-SNTIGAIYSPT 110 green anole
Q90743        72 --------------------S---SHQLEK------------------RKCNTATCVTQRLADFLVRS-SSNIGAIYSPT 109 chicken
XP_005998925  74 ------------------------SHPIEK------------------RKCNTATCVTQRLADFLIRA-NGNMRALHSPT 110 coelacanth
XP_015207527  72 ------------------------SHRMEK------------------RKCNTATCVTQRLADFLIRS-SNTVGTVYSPT 108 spotted gar
XP_007235079  69 -------------------SQ---QHHIEK------------------RRCNTATCVTQRLADYLVRS-SNTMGTVYSPT 107 Mexican tetra
6_pfamImport  74 ------------------------SHHMQK------------------RKCNTATCVTQRLADFLVRS-SNTIGTVYAPT 110
4_pfamImport  44 vslfdtdretrttskpdpdTV---FTLLLQtilqkar-----ekraaqRGCQLGTCQVHNLVNKLYRMgQSNGKDESKKA 115
XP_003455427  61 sgpqqd----rlaktlptpSS---FGLNIRsrrs----------tssqSGCFLITCIYHDLFHRLVQIkKNEQTDTTAPT 123 Nile tilapia
NP_001313638  55 vrpdd------vkdnlrphSS---TDISIRakrskns-----inqsrrSGCSLGTCTVHVLAHRLHDL-NNKLKIGNAPV 119 zebrafish
XP_003773643 141 NkISPQGYGRRRR 153 Tasmanian devil
XP_003220825 111 N-VGSNTYGKRdk 122 green anole
Q90743       110 N-VGSNTYGKRdt 121 chicken
XP_005998925 111 N-VGAYTYGKRDS 122 coelacanth
XP_015207527 109 N-VGSNTYGKRDs 120 spotted gar
XP_007235079 108 N-VGSSTYGKRev 119 Mexican tetra
6_pfamImport 111 N-VGSGTYGKR-- 120
4_pfamImport 116 N--DPTGYGR--- 123
XP_003455427 124 SkIGRNGYGRRRR 136 Nile tilapia
NP_001313638 120 DkINPYGYGRRRR 132 zebrafish
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