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Zfp947 zinc finger protein 947 [ Mus musculus (house mouse) ]

Gene ID: 210853, updated on 8-Feb-2024

Summary

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Official Symbol
Zfp947provided by MGI
Official Full Name
zinc finger protein 947provided by MGI
Primary source
MGI:MGI:3646759
See related
Ensembl:ENSMUSG00000063383 AllianceGenome:MGI:3646759
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm4769; EG210853; 6720451E15
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
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Genomic context

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Location:
17 A3.3; 17 11.4 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (22363336..22385153, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (22144355..22166172, complement)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene sperm motility kinase Y pseudogene Neighboring gene zinc finger protein 947 pseudogene Neighboring gene STARR-seq mESC enhancer starr_42022 Neighboring gene STARR-seq mESC enhancer starr_42023 Neighboring gene STARR-seq mESC enhancer starr_42024 Neighboring gene sorting nexin 4 pseudogene Neighboring gene predicted gene, 52309 Neighboring gene zinc finger protein 994

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
  2. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC141638

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
zinc finger protein 947

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177596.4 → NP_808264.1  zinc finger protein 947

    See identical proteins and their annotated locations for NP_808264.1

    Status: VALIDATED

    Source sequence(s)
    AC154707
    Consensus CDS
    CCDS49999.1
    UniProtKB/TrEMBL
    Q8BIQ6
    Related
    ENSMUSP00000079137.6, ENSMUST00000080249.6
    Conserved Domains (3) summary
    COG5048
    Location:204 → 436
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:353 → 373
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:12 → 52
    KRAB; KRAB box

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    22363336..22385153 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030249621.1 → XP_030105481.1  zinc finger protein 947 isoform X1

    UniProtKB/TrEMBL
    Q8BIQ6
    Conserved Domains (3) summary
    COG5048
    Location:204 → 436
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:353 → 373
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:12 → 52
    KRAB; KRAB box
Nucleotide Protein Strain
Heading Accession and Version

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