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CG9993 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 37358, updated on 4-Apr-2024

Summary

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Official Symbol
CG9993provided by FlyBase
Primary source
FLYBASE:FBgn0034553
Locus tag
Dmel_CG9993
See related
AllianceGenome:FB:FBgn0034553
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG9993
Summary
Predicted to enable long-chain fatty acid-CoA ligase activity. Predicted to be involved in fatty-acyl-CoA biosynthetic process and long-chain fatty acid metabolic process. Is expressed in anal pad primordium; embryonic anal pad; and hindgut proper primordium. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
57B3-57B3; 2-92 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (20850146..20852125, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (16737651..16739630, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44667 Neighboring gene uncharacterized protein Neighboring gene Carbonic anhydrase 14 Neighboring gene Daisho1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Enzymatic and genetic characterization of firefly luciferase and Drosophila CG6178 as a fatty acyl-CoA synthetase. Oba Y, et al. Biosci Biotechnol Biochem, 2005 Apr. PMID 15849423
  2. Using FlyAtlas to identify better Drosophila melanogaster models of human disease. Chintapalli VR, et al. Nat Genet, 2007 Jun. PMID 17534367
  3. The Genetic Architecture of Ovariole Number in Drosophila melanogaster: Genes with Major, Quantitative, and Pleiotropic Effects. Lobell AS, et al. G3 (Bethesda), 2017 Jul 5. PMID 28550012, Free PMC Article
  4. Transcriptional signature of an adult brain tumor in Drosophila. Loop T, et al. BMC Genomics, 2004 Apr 16. PMID 15090076, Free PMC Article
  5. Evidence for 26 distinct acyl-coenzyme A synthetase genes in the human genome. Watkins PA, et al. J Lipid Res, 2007 Dec. PMID 17762044

See all (32) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables CoA-ligase activity TAS
Traceable Author Statement
more info
 PubMed 
enables fatty acid ligase activity TAS
Traceable Author Statement
more info
 PubMed 
enables long-chain fatty acid-CoA ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in fatty acid biosynthetic process TAS
Traceable Author Statement
more info
 PubMed 
involved_in fatty-acyl-CoA biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in long-chain fatty acid metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG9993-PA
NP_611518.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    20850146..20852125 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_137674.2 → NP_611518.1  uncharacterized protein Dmel_CG9993 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_611518.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    C5WLU6, Q9W2R1
    Related
    FBpp0071488
    Conserved Domains (2) summary
    COG0318
    Location:21 → 532
    CaiC; Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II [Lipid transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism]
    cl17068
    Location:45 → 528
    AFD_class_I; Adenylate forming domain, Class I superfamily
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8MYZ4 Q8MYZ4
Q9W2R1 Q9W2R1

Gene LinkOut

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