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mkg-p monkey king protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38955, updated on 4-Apr-2024

Summary

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Official Symbol
mkg-pprovided by FlyBase
Official Full Name
monkey king proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0035889
Locus tag
Dmel_CG7163
See related
AllianceGenome:FB:FBgn0035889
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG7163; Dmel\CG7163; MK; mkg; mkg-r; mkgr; MKI; TUTase6
Summary
Predicted to enable RNA uridylyltransferase activity. Predicted to be involved in mRNA polyadenylation. Predicted to be active in cytosol. Is expressed in organism. Human ortholog(s) of this gene implicated in liver benign neoplasm. Orthologous to human TUT4 (terminal uridylyl transferase 4). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See mkg-p in Genome Data Viewer
Location:
66C11-66C11; 3-24 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (8402168..8405277, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (8395268..8398377, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Jonah 66Ci Neighboring gene Jonah 66Cii Neighboring gene uncharacterized protein Neighboring gene tRNA 2'-phosphotransferase Neighboring gene uncharacterized protein Neighboring gene Outer segment 1 Neighboring gene Exocyst 70 Neighboring gene matrimony

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Duplication-degeneration as a mechanism of gene fission and the origin of new genes in Drosophila species. Wang W, et al. Nat Genet, 2004 May. PMID 15064762
  2. Evolution of miRNA Tailing by 3' Terminal Uridylyl Transferases in Metazoa. Modepalli V, et al. Genome Biol Evol, 2017 Jun 1. PMID 28633361, Free PMC Article
  3. A deficiency screen of the major autosomes identifies a gene (matrimony) that is haplo-insufficient for achiasmate segregation in Drosophila oocytes. Harris D, et al. Genetics, 2003 Oct. PMID 14573476, Free PMC Article
  4. Repetitive element-mediated recombination as a mechanism for new gene origination in Drosophila. Yang S, et al. PLoS Genet, 2008 Jan. PMID 18208328, Free PMC Article
  5. A gain-of-function screen identifying genes required for vein formation in the Drosophila melanogaster wing. Molnar C, et al. Genetics, 2006 Nov. PMID 16980395, Free PMC Article

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables RNA uridylyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA uridylyltransferase activity ISO
Inferred from Sequence Orthology
more info
 PubMed 
enables nucleotidyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in RNA 3' uridylation IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
monkey king protein
Names
3' terminal uridylyl transferase 6
CG7163-PA
CG7163-PB
CG7163-PD
mkg-p-PA
mkg-p-PB
mkg-p-PD
monkey king
monkey-king
NP_001286981.1
NP_648219.1
NP_729375.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    8402168..8405277 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_168272.2 → NP_729375.1  monkey king protein, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_729375.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q6Q376, Q95U58
    Related
    FBpp0076387
    Conserved Domains (1) summary
    cd05402
    Location:104 → 216
    NT_PAP_TUTase; Nucleotidyltransferase (NT) domain of poly(A) polymerases and terminal uridylyl transferases

  2. NM_001300052.1 → NP_001286981.1  monkey king protein, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001286981.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q6Q376, Q95U58
    Conserved Domains (1) summary
    cd05402
    Location:104 → 216
    NT_PAP_TUTase; Nucleotidyltransferase (NT) domain of poly(A) polymerases and terminal uridylyl transferases

  3. NM_139962.4 → NP_648219.1  monkey king protein, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_648219.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q6Q376, Q95U58
    Related
    FBpp0076388
    Conserved Domains (1) summary
    cd05402
    Location:104 → 216
    NT_PAP_TUTase; Nucleotidyltransferase (NT) domain of poly(A) polymerases and terminal uridylyl transferases
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6Q376 Q6Q376
Q95U58 Q95U58

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