TBX2 T-box transcription factor 2 [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: TBX2provided by VGNC
Official Full Name: T-box transcription factor 2provided by VGNC
Primary source: VGNC:VGNC:47171
See related: Ensembl:ENSCAFG00845027360
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 9

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	9	NC_051813.1 (36048354..36057619, complement)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	9	NC_006591.4 (34466401..34475666, complement)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	9	NC_049230.1 (35202696..35211975, complement)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	9	NC_049269.1 (34829267..34838524, complement)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	9	NC_049750.1 (35114884..35124167, complement)

Chromosome 9 - NC_051813.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

PMC311067P4 (e-PCR)
- UniSTS:272875

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info	PubMed
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cell fate specification	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: T-box transcription factor TBX2; LOW QUALITY PROTEIN: T-box transcription factor TBX2

Names: T-box 2 transcription factor; T-box protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051813.1 Reference ROS_Cfam_1.0

Range

36048354..36057619 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038677197.1 → XP_038533125.1 T-box transcription factor TBX2

UniProtKB/Swiss-Prot

Q863A2

UniProtKB/TrEMBL

A0A8C0PSJ3, A0A8C0QTR6

Related

ENSCAFP00845037798.1, ENSCAFT00845048190.1

Conserved Domains (3) summary

PHA03307
Location:300 → 466

PHA03307; transcriptional regulator ICP4; Provisional

pfam12598
Location:305 → 383

TBX; T-box transcription factor

cd20188
Location:103 → 287

T-box_TBX2_3-like; DNA-binding domain of T-box transcription factor 2 and 3, and related T-box proteins

Alternate UMICH_Zoey_3.1

Genomic

NC_049269.1 Alternate UMICH_Zoey_3.1

Range

34829267..34838524 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038486167.1 → XP_038342095.1 T-box transcription factor TBX2

Conserved Domains (3) summary

PHA03307
Location:300 → 466

PHA03307; transcriptional regulator ICP4; Provisional

pfam12598
Location:305 → 383

TBX; T-box transcription factor

cd20188
Location:103 → 287

T-box_TBX2_3-like; DNA-binding domain of T-box transcription factor 2 and 3, and related T-box proteins

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049750.1 Alternate UNSW_CanFamBas_1.0

Range

35114884..35124167 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038611952.1 → XP_038467880.1 LOW QUALITY PROTEIN: T-box transcription factor TBX2

Conserved Domains (3) summary

PHA03307
Location:300 → 466

PHA03307; transcriptional regulator ICP4; Provisional

pfam12598
Location:305 → 383

TBX; T-box transcription factor

cd20188
Location:103 → 287

T-box_TBX2_3-like; DNA-binding domain of T-box transcription factor 2 and 3, and related T-box proteins

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049230.1 Alternate UU_Cfam_GSD_1.0

Range

35202696..35211975 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038547986.1 → XP_038403914.1 T-box transcription factor TBX2

UniProtKB/Swiss-Prot

Q863A2

UniProtKB/TrEMBL

A0A8C0PSJ3, A0A8C0QTR6

Conserved Domains (3) summary

PHA03307
Location:300 → 466

PHA03307; transcriptional regulator ICP4; Provisional

pfam12598
Location:305 → 383

TBX; T-box transcription factor

cd20188
Location:103 → 287

T-box_TBX2_3-like; DNA-binding domain of T-box transcription factor 2 and 3, and related T-box proteins

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006591.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

34466401..34475666 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038608344.1 → XP_038464272.1 T-box transcription factor TBX2

UniProtKB/Swiss-Prot

Q863A2

UniProtKB/TrEMBL

A0A8C0PSJ3, A0A8C0QTR6

Conserved Domains (3) summary

PHA03307
Location:300 → 466

PHA03307; transcriptional regulator ICP4; Provisional

pfam12598
Location:305 → 383

TBX; T-box transcription factor

cd20188
Location:103 → 287

T-box_TBX2_3-like; DNA-binding domain of T-box transcription factor 2 and 3, and related T-box proteins

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NM_001005249.2: Suppressed sequence

Description

NM_001005249.2: This RefSeq was removed because there is insufficient transcript data. The RefSeq cannot be derived from the draft reference genome sequence because it appears to contain errors such that the correct protein cannot be represented.