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    sra-2 Serpentine receptor class alpha-2 [ Caenorhabditis elegans ]

    Gene ID: 191773, updated on 12-Jun-2024

    Summary

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    Gene symbol
    sra-2
    Gene description
    Serpentine receptor class alpha-2
    Locus tag
    CELE_AH6.6
    See related
    AllianceGenome:WB:WBGene00005028
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in body wall musculature; enteric muscle; head; and hypodermis. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See sra-2 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    3
    Sequence:
    Chromosome: II; NC_003280.10 (9528780..9529862)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Zinc finger protein mex-6 Neighboring gene pseudo Neighboring gene pseudo Neighboring gene Serpentine receptor class alpha-9

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The C. elegans G-protein-coupled receptor SRA-13 inhibits RAS/MAPK signalling during olfaction and vulval development. Battu G, et al. Development, 2003 Jun. PMID 12736202
    2. Divergent seven transmembrane receptors are candidate chemosensory receptors in C. elegans. Troemel ER, et al. Cell, 1995 Oct 20. PMID 7585938
    3. Identification of a nematode chemosensory gene family. Chen N, et al. Proc Natl Acad Sci U S A, 2005 Jan 4. PMID 15618405, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in detection of chemical stimulus involved in sensory perception IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in detection of chemical stimulus involved in sensory perception of smell IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in sensory perception of chemical stimulus IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Serpentine receptor class alpha-2
    NP_496044.1
    • Predicted

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      9528780..9529862
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_063643.1 → NP_496044.1  Serpentine receptor class alpha-2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_496044.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q09204
      Conserved Domains (1) summary
      pfam02117
      Location:1 → 328
      7TM_GPCR_Sra; Serpentine type 7TM GPCR chemoreceptor Sra
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    2123261B.1
    Q09204.1

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