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    Vmn1r4 vomeronasal 1 receptor 4 [ Mus musculus (house mouse) ]

    Gene ID: 171194, updated on 8-Feb-2024

    Summary

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    Official Symbol
    Vmn1r4provided by MGI
    Official Full Name
    vomeronasal 1 receptor 4provided by MGI
    Primary source
    MGI:MGI:2159457
    See related
    Ensembl:ENSMUSG00000071893 AllianceGenome:MGI:2159457
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    V1rc21; C230065D10Rik
    Summary
    Predicted to enable pheromone binding activity and pheromone receptor activity. Predicted to act upstream of or within response to pheromone. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See Vmn1r4 in Genome Data Viewer
    Location:
    6 B3; 6 27.76 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (56901078..56934593)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (56923914..56957608)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_15993 Neighboring gene FK506 binding protein 9 Neighboring gene 5'-nucleotidase, cytosolic III Neighboring gene STARR-seq mESC enhancer starr_15995 Neighboring gene predicted gene, 53332 Neighboring gene STARR-positive B cell enhancer ABC_E8830 Neighboring gene STARR-seq mESC enhancer starr_15996 Neighboring gene vomeronasal 1 receptor 5 Neighboring gene vomeronasal 1 receptor 6

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Multiple new and isolated families within the mouse superfamily of V1r vomeronasal receptors. Rodriguez I, et al. Nat Neurosci, 2002 Feb. PMID 11802169
    2. Manual annotation and analysis of the defensin gene cluster in the C57BL/6J mouse reference genome. Amid C, et al. BMC Genomics, 2009 Dec 15. PMID 20003482, Free PMC Article
    3. Extreme variability among mammalian V1R gene families. Young JM, et al. Genome Res, 2010 Jan. PMID 19952141, Free PMC Article
    4. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables pheromone binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables pheromone receptor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within response to pheromone ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    vomeronasal 1 receptor 4
    Names
    vomernasal 1 receptor Vmn1r4
    vomeronasal 1 receptor, C21
    vomeronasal type 1 receptor C21

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_134176.1 → NP_598937.1  vomeronasal 1 receptor 4

      See identical proteins and their annotated locations for NP_598937.1

      Status: PROVISIONAL

      Source sequence(s)
      AY065477
      Consensus CDS
      CCDS20172.1
      UniProtKB/TrEMBL
      F6MAP9, F6MAR5, Q8R2D3
      Related
      ENSMUSP00000094369.4, ENSMUST00000096612.4
      Conserved Domains (2) summary
      cd14964
      Location:5 → 28
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:5 → 294
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      56901078..56934593
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036165898.1 → XP_036021791.1  vomeronasal 1 receptor 4 isoform X1

      UniProtKB/TrEMBL
      F6MAP9, F6MAR5, Q8R2D3
      Related
      ENSMUSP00000135323.2, ENSMUST00000176838.2
      Conserved Domains (2) summary
      cd14964
      Location:5 → 28
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:5 → 294
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    2. XM_006505672.2 → XP_006505735.1  vomeronasal 1 receptor 4 isoform X1

      See identical proteins and their annotated locations for XP_006505735.1

      UniProtKB/TrEMBL
      F6MAP9, F6MAR5, Q8R2D3
      Related
      ENSMUSP00000153919.2, ENSMUST00000227073.2
      Conserved Domains (2) summary
      cd14964
      Location:5 → 28
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:5 → 294
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    RNA

    1. XR_004942915.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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