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    Mcptl mast cell protease-like [ Mus musculus (house mouse) ]

    Gene ID: 17233, updated on 23-Nov-2023

    Summary

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    Official Symbol
    Mcptlprovided by MGI
    Official Full Name
    mast cell protease-likeprovided by MGI
    Primary source
    MGI:MGI:102792
    See related
    AllianceGenome:MGI:102792
    Gene type
    protein coding
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    MMCP-L
    Summary
    Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]
    Annotation information
    not in current annotation release
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    Genomic context

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    Location:
    14 C2; 14

    Bibliography

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    Related articles in PubMed

    1. Cloning of the cDNA and gene for mouse mast cell protease 4. Demonstration of its late transcription in mast cell subclasses and analysis of its homology to subclass-specific neutral proteases of the mouse and rat. Serafin WE, et al. J Biol Chem, 1991 Jan 25. PMID 1988455
    2. Characterization of mouse mast cell protease-8, the first member of a novel subfamily of mouse mast cell serine proteases, distinct from both the classical chymases and tryptases. Lützelschwab C, et al. Eur J Immunol, 1998 Mar. PMID 9541598
    3. Genes for mast-cell serine protease and their molecular evolution. Huang R, et al. Immunogenetics, 1994. PMID 7959952
    4. IL-17-driven intestinal fibrosis is inhibited by Itch-mediated ubiquitination of HIC-5. Paul J, et al. Mucosal Immunol, 2018 Mar. PMID 28612841
    5. Rab geranylgeranyl transferase alpha mutation in the gunmetal mouse reduces Rab prenylation and platelet synthesis. Detter JC, et al. Proc Natl Acad Sci U S A, 2000 Apr 11. PMID 10737774, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables heparin binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables peptide binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables serine-type endopeptidase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein catabolic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in intracellular membrane-bounded organelle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    mast cell protease-like protein

    NCBI Reference Sequences (RefSeq)

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    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_008573.1: Suppressed sequence

      Description
      NM_008573.1: This RefSeq record was removed by NCBI staff. Contact info@ncbi.nlm.nih.gov for further information.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q00356.1 GenPept UniProtKB/Swiss-Prot:Q00356

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