Lynch syndrome 8
- Synonyms
- Colorectal cancer, hereditary nonpolyposis, type 8
Summary
Excerpted from the GeneReview:- Full text of GeneReview (by section):
- Summary
- Diagnosis
- Clinical Characteristics
- Genetically Related (Allelic) Disorders
- Differential Diagnosis
- Management
- Genetic Counseling
- Resources
- Molecular Genetics
- Chapter Notes
- References
- Authors:
- Gregory Idos
- Laura Valle
- view full author information
Available tests
Clinical features
Help- Abnormality of the digestive system
- Adenomatous colonic polyposis
Adenomatous colonic polyposis
- MedGen UID: 358118
- Concept ID: C1868071
- Finding: Finding
Abnormality of the digestive system
- Colon cancer
Colon cancer
- MedGen UID: 2839
- Concept ID: C0007102
- Finding: Neoplastic Process
Abnormality of the digestive system
- Hereditary nonpolyposis colorectal carcinoma
Hereditary nonpolyposis colorectal carcinoma
- MedGen UID: 870541
- Concept ID: C4024989
- Finding: Neoplastic Process
Abnormality of the digestive system
- Adenomatous colonic polyposis
- Abnormality of the genitourinary system
- Endometrial carcinoma
Endometrial carcinoma
- MedGen UID: 96903
- Concept ID: C0476089
- Finding: Neoplastic Process
Abnormality of the genitourinary system
- Endometrial carcinoma
- NICE, 2021UK NICE Guideline NG151, Colorectal cancer, 2021
- NICE, 2020UK NICE Diagnostics Guidance DG42, Testing strategies for Lynch syndrome in people with endometrial cancer, 2020
- ACMG ACT, 2019American College of Medical Genetics and Genomics, Genomic Testing (Secondary Findings) ACT Sheet, MLH1, MSH2, MSH6, PMS2, EPCAM Pathogenic Variants, Lynch Syndrome (Hereditary Non-polyposis Colon Cancer [HNPCC]), 2019
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