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Inhibition of MCP-1 in LPS-stimulated human whole blood incubate for 24 hrs by immuno assay
Assay data:29 Active, 23 Activity ≤ 1 µM, 29 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested
Binding affinity to human CCL2 assessed as off-rate constant incubated for 3 mins by surface plasmon resonance analysis
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Binding affinity to human CCL2 assessed as on-rate constant incubated for 3 mins by surface plasmon resonance analysis
Binding affinity to human CCL2 assessed as dissociation constant incubated for 3 mins by surface plasmon resonance analysis
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Binding affinity to human CCL2 at 100 uM by glycan microarray analysis
Assay data:12 Tested
LPS-PBMC assay (MCP-1)
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
In vitro inhibition of MCP-1 in Lipopolysaccharide-stimulated human whole blood
SummaryCompounds, ActiveRelated BioAssays by Target
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
Binding affinity to CCL2 (unknown origin) assessed as inhibition of CXCL12 -induced increase in intracellular calcium level in EGFP-tagged CCR2 expressing HEK cells at 10 uM
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
SummaryRelated BioAssays by Same Project
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
SummaryPubMed Citation
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
Binding affinity to human recombinant CCL2 by surface plasmon resonance assay
Assay data:3 Tested
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