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Select item 69905461.

Disruption of Midkine gene reduces traumatic brain injury through the modulation of neuroinflammation

Seiya Takada, Harutoshi Sakakima, Takahiro Matsuyama, Shotaro Otsuka, Kazuki Nakanishi, Kosuke Norimatsu, Yuki Itashiki, Akira Tani, Kiyoshi Kikuchi

J Neuroinflammation. 2020; 17: 40. Published online 2020 Jan 29. doi: 10.1186/s12974-020-1709-8

PMCID:: PMC6990546

Abstract Article PDF–1.8M

Select item 55956382.

Midkine in the Mouse Ventral Tegmental Area Limits Ethanol Intake and Ccl2 Gene Expression

Hu Chen, Donghong He, Amy W. Lasek

Genes Brain Behav. Author manuscript; available in PMC 2018 Sep 1.

Published in final edited form as: Genes Brain Behav. 2017 Sep; 16(7): 699–708. Published online 2017 May 2. doi: 10.1111/gbb.12384

PMCID:: PMC5595638

Abstract Article PDF–1.0M

Select item 51649013.

Midkine Is a Novel Regulator of Amphetamine-Induced Striatal Gliosis and Cognitive Impairment: Evidence for a Stimulus-Dependent Regulation of Neuroinflammation by Midkine

Marta Vicente-Rodríguez, Rosalía Fernández-Calle, Esther Gramage, Carmen Pérez-García, María P. Ramos, Gonzalo Herradón

Mediators Inflamm. 2016; 2016: 9894504. Published online 2016 Dec 4. doi: 10.1155/2016/9894504

PMCID:: PMC5164901

Abstract Article PDF–6.7M

Select item 45201554.

Midkine Regulates BP through Cytochrome P450–Derived Eicosanoids

Yuka Sato, Waichi Sato, Shoichi Maruyama, Christopher S. Wilcox, John R. Falck, Tomohiro Masuda, Tomoki Kosugi, Hiroshi Kojima, Kayaho Maeda, Kazuhiro Furuhashi, Masahiko Ando, Enyu Imai, Seiichi Matsuo, Kenji Kadomatsu

J Am Soc Nephrol. 2015 Aug; 26(8): 1806–1815. Published online 2014 Nov 5. doi: 10.1681/ASN.2013121259

PMCID:: PMC4520155

Abstract Article

Select item 39250295.

The midkine family of growth factors: diverse roles in nervous system formation and maintenance

C Winkler, S Yao

Br J Pharmacol. 2014 Feb; 171(4): 905–912. Published online 2014 Jan 24. doi: 10.1111/bph.12462

PMCID:: PMC3925029

Abstract Article PDF–529K

Select item 39250286.

Involvement of midkine in neuroblastoma tumourigenesis

S Kishida, K Kadomatsu

Br J Pharmacol. 2014 Feb; 171(4): 896–904. Published online 2014 Jan 24. doi: 10.1111/bph.12442

PMCID:: PMC3925028

Abstract Article PDF–722K

Select item 39250267.

Midkine in nephrogenesis, hypertension and kidney diseases

Waichi Sato, Yuka Sato

Br J Pharmacol. 2014 Feb; 171(4): 879–887. Published online 2014 Jan 24. doi: 10.1111/bph.12418

PMCID:: PMC3925026

Abstract Article PDF–522K

Select item 39250258.

The role of midkine in skeletal remodelling

A Liedert, T Schinke, A Ignatius, M Amling

Br J Pharmacol. 2014 Feb; 171(4): 870–878. Published online 2014 Jan 24. doi: 10.1111/bph.12412

PMCID:: PMC3925025

Abstract Article PDF–783K

Select item 38683079.

Age Dependence of Lung Mesenchymal Stromal Cell Dynamics Following Pneumonectomy

Julia A. Paxson, Alisha M. Gruntman, Airiel M. Davis, Christopher M. Parkin, Edward P. Ingenito, Andrew M. Hoffman

Stem Cells Dev. 2013 Dec 15; 22(24): 3214–3225. Published online 2013 Jul 29. doi: 10.1089/scd.2012.0477

PMCID:: PMC3868307

Abstract Article PDF–657K

Select item 377637810.

Midkine Mediates Intercellular Crosstalk between Drug-Resistant and Drug-Sensitive Neuroblastoma Cells In Vitro and In Vivo

Fei Chu, Jessica A. Naiditch, Sandra Clark, Yi-Yong Qiu, Xin Zheng, Timothy B. Lautz, Janette L. Holub, Pauline M. Chou, Michael Czurylo, Mary Beth Madonna

ISRN Oncol. 2013; 2013: 518637. Published online 2013 Sep 3. doi: 10.1155/2013/518637

PMCID:: PMC3776378

Abstract Article PDF–2.0M

Select item 374546211.

Inhibition of the Growth Factor MDK/Midkine by a Novel Small Molecule Compound to Treat Non-Small Cell Lung Cancer

Huifang Hao, Yutaka Maeda, Takuya Fukazawa, Tomoki Yamatsuji, Munenori Takaoka, Xiao-Hong Bao, Junji Matsuoka, Tatsuo Okui, Tsuyoshi Shimo, Nagio Takigawa, Yasuko Tomono, Motowo Nakajima, Iris M. Fink-Baldauf, Sandra Nelson, William Seibel, Ruben Papoian, Jeffrey A. Whitsett, Yoshio Naomoto

PLoS One. 2013; 8(8): e71093. Published online 2013 Aug 16. doi: 10.1371/journal.pone.0071093

PMCID:: PMC3745462

Abstract Article PDF–907K

Select item 367434612.

A caspase-3 ‘death-switch' in colorectal cancer cells for induced and synchronous tumor apoptosis in vitro and in vivo facilitates the development of minimally invasive cell death biomarkers

K L Simpson, C Cawthorne, C Zhou, C L Hodgkinson, M J Walker, F Trapani, M Kadirvel, G Brown, M J Dawson, M MacFarlane, K J Williams, A D Whetton, C Dive

Cell Death Dis. 2013 May; 4(5): e613. Published online 2013 May 2. doi: 10.1038/cddis.2013.137

PMCID:: PMC3674346

Abstract Article PDF–1.6M

Select item 302321913.

Midkine, a heparin-binding protein, is increased in the diabetic mouse kidney postmenopause

Maggie K. Diamond-Stanic, Melissa J. Romero-Aleshire, Patricia B. Hoyer, Kevin Greer, James B. Hoying, Heddwen L. Brooks

Am J Physiol Renal Physiol. 2011 Jan; 300(1): F139–F146. Published online 2010 Nov 3. doi: 10.1152/ajprenal.00249.2010

PMCID:: PMC3023219

Abstract Article

Select item 268911014.

The growth factor midkine regulates the renin-angiotensin system in mice

Akinori Hobo, Yukio Yuzawa, Tomoki Kosugi, Noritoshi Kato, Naoto Asai, Waichi Sato, Shoichi Maruyama, Yasuhiko Ito, Hiroyuki Kobori, Shinya Ikematsu, Akira Nishiyama, Seiichi Matsuo, Kenji Kadomatsu

J Clin Invest. 2009 Jun 1; 119(6): 1616–1625. Published online 2009 May 18. doi: 10.1172/JCI37249

PMCID:: PMC2689110

Abstract Article PDF–3.1M

Select item 226884215.

Inhibition of midkine alleviates experimental autoimmune encephalomyelitis through the expansion of regulatory T cell population

Jinyan Wang, Hideyuki Takeuchi, Yoshifumi Sonobe, Shijie Jin, Tetsuya Mizuno, Shin Miyakawa, Masatoshi Fujiwara, Yoshikazu Nakamura, Takuma Kato, Hisako Muramatsu, Takashi Muramatsu, Akio Suzumura

Proc Natl Acad Sci U S A. 2008 Mar 11; 105(10): 3915–3920. Published online 2008 Mar 4. doi: 10.1073/pnas.0709592105

PMCID:: PMC2268842

Abstract Article PDF–1001K

Select item 212037316.

Midkine (MK), a heparin-binding growth/differentiation factor, is regulated by retinoic acid and epithelial-mesenchymal interactions in the developing mouse tooth, and affects cell proliferation and morphogenesis

J Cell Biol. 1995 Apr 1; 129(1): 267–281. doi: 10.1083/jcb.129.1.267

PMCID:: PMC2120373

Summary PDF–11M

Select item 211602917.

A retinoic acid responsive gene MK found in the teratocarcinoma system is expressed in spatially and temporally controlled manner during mouse embryogenesis

J Cell Biol. 1990 Mar 1; 110(3): 607–616. doi: 10.1083/jcb.110.3.607

PMCID:: PMC2116029

Summary PDF–5.4M

Select item 159265418.

Growth Factor Midkine Is Involved in the Pathogenesis of Diabetic Nephropathy

Tomoki Kosugi, Yukio Yuzawa, Waichi Sato, Hanayo Kawai, Seiichi Matsuo, Yoshifumi Takei, Takashi Muramatsu, Kenji Kadomatsu

Am J Pathol. 2006 Jan; 168(1): 9–19. doi: 10.2353/ajpath.2006.050488

PMCID:: PMC1592654

Abstract Article PDF–2.0M

Select item 13404519.

Nuclear Targeting by the Growth Factor Midkine

Yoshihisa Shibata, Takashi Muramatsu, Makoto Hirai, Tatsuya Inui, Terutoshi Kimura, Hidehiko Saito, Lynn M. McCormick, Guojun Bu, Kenji Kadomatsu

Mol Cell Biol. 2002 Oct; 22(19): 6788–6796. doi: 10.1128/MCB.22.19.6788-6796.2002

PMCID:: PMC134045

Abstract Article PDF–437K

Select item 884955120.

HSP70 Inhibition Blocks Adaptive Resistance and Synergizes with MEK Inhibition for the Treatment of NRAS-Mutant Melanoma

Joshua L.D. Parris, Thibaut Barnoud, Julia I.-Ju Leu, Jessica C. Leung, Weili Ma, Nicole A. Kirven, Adi Naryana Reddy Poli, Andrew V. Kossenkov, Qin Liu, Joseph M. Salvino, Donna L. George, Ashani T. Weeraratna, Qing Chen, Maureen E. Murphy

Cancer Res Commun. 2021 Oct; 1(1): 17–29. Published online 2021 Oct 13. doi: 10.1158/2767-9764.CRC-21-0033