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Select item 79420111.

Stable DNMT3L overexpression in SH-SY5Y neurons recreates a facet of the genome-wide Down syndrome DNA methylation signature

Benjamin I. Laufer, J. Antonio Gomez, Julia M. Jianu, Janine M. LaSalle

Epigenetics Chromatin. 2021; 14: 13. Published online 2021 Mar 9. doi: 10.1186/s13072-021-00387-7

PMCID:: PMC7942011

Abstract Article PDF–3.7M

Select item 20808242.

DNA Methylation Profile at the DNMT3L Promoter: A Potential Biomarker for Cervical Cancer

Gopinathan Gokul, Bhimana Gautami, Surapaneni Malathi, A. Pavani Sowjanya, Usha Rani Poli, Meenakshi Jain, Gayatri Ramakrishna, Sanjeev Khosla

Epigenetics. Author manuscript; available in PMC 2007 Nov 19.

Published in final edited form as: Epigenetics. 2007 Apr-Jun; 2(2): 80–85. Published online 2006 Dec 7. doi: 10.4161/epi.2.2.3692

PMCID:: PMC2080824

Abstract Article PDF–353K

Select item 108379933.

DNMT3L inhibits hepatocellular carcinoma progression through DNA methylation of CDO1: insights from big data to basic research

Xiaokai Yan, Yao Qi, Xinyue Yao, Nanjing Zhou, Xinxin Ye, Xing Chen

J Transl Med. 2024; 22: 128. Published online 2024 Feb 2. doi: 10.1186/s12967-024-04939-9

PMCID:: PMC10837993

Abstract Article PDF–8.6M

Select item 80463014.

Decoding the Genetic Alterations in Genes of DNMT Family (DNA Methyl-Transferase) and their Association with Head and Neck Squamous Cell Carcinoma

Tahreem Fathima, Paramasivam Arumugam, Smiline Girija AS, J Vijayashree Priyadharsini

Asian Pac J Cancer Prev. 2020 Dec; 21(12): 3605–3612. doi: 10.31557/APJCP.2020.21.12.3605

PMCID:: PMC8046301

Abstract Article PDF–740K

Select item 71449125.

Structural insights into CpG-specific DNA methylation by human DNA methyltransferase 3B

Chien-Chu Lin, Yi-Ping Chen, Wei-Zen Yang, James C K Shen, Hanna S Yuan

Nucleic Acids Res. 2020 Apr 17; 48(7): 3949–3961. Published online 2020 Feb 21. doi: 10.1093/nar/gkaa111

PMCID:: PMC7144912

Abstract Article PDF–9.2M

Select item 29379406.

The Inherent Processivity of the Human de Novo Methyltransferase 3A (DNMT3A) Is Enhanced by DNMT3L

Celeste Holz-Schietinger, Norbert O. Reich

J Biol Chem. 2010 Sep 17; 285(38): 29091–29100. Published online 2010 Jul 14. doi: 10.1074/jbc.M110.142513

PMCID:: PMC2937940

Abstract Article PDF–2.7M

Select item 1392447.

The DNA methyltransferase-like protein DNMT3L stimulates de novo methylation by Dnmt3a

Frédéric Chédin, Michael R. Lieber, Chih-Lin Hsieh

Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16916–16921. Published online 2002 Dec 12. doi: 10.1073/pnas.262443999

PMCID:: PMC139244

Abstract Article PDF–317K

Select item 1342418.

Imprinting regulator DNMT3L is a transcriptional repressor associated with histone deacetylase activity

Ulla Aapola, Ingrid Liiv, Pärt Peterson

Nucleic Acids Res. 2002 Aug 15; 30(16): 3602–3608. doi: 10.1093/nar/gkf474

PMCID:: PMC134241

Abstract Article PDF–162K

Select item 68158179.

EGR1 interacts with DNMT3L to inhibit the transcription of miR‐195 and plays an anti‐apoptotic role in the development of gastric cancer

Yang Yang, Fei Wu, Jing Zhang, Ruifang Sun, Fang Li, Yulong Li, Su’e Chang, Lumin Wang, Xiaofei Wang, Liying Liu, Chen Huang

J Cell Mol Med. 2019 Nov; 23(11): 7372–7381. Published online 2019 Sep 12. doi: 10.1111/jcmm.14597

PMCID:: PMC6815817

Abstract Article PDF–1.2M

Select item 498632810.

Global hypermethylation in fetal cortex of Down syndrome due to DNMT3L overexpression

Jie Lu, Monika Mccarter, Gewei Lian, Giuseppe Esposito, Elena Capoccia, Laurent C. Delli-Bovi, Jonathan Hecht, Volney Sheen

Hum Mol Genet. 2016 May 1; 25(9): 1714–1727. Published online 2016 Feb 23. doi: 10.1093/hmg/ddw043

PMCID:: PMC4986328

Abstract Article PDF–1.3M

Select item 403228611.

DNA Methyl Transferase (DNMT) Gene Polymorphisms Could Be a Primary Event in Epigenetic Susceptibility to Schizophrenia

Koramannil Radha Saradalekshmi, Nanoth Vellichiramal Neetha, Sanish Sathyan, Indu V. Nair, Chandrasekharan M. Nair, Moinak Banerjee

PLoS One. 2014; 9(5): e98182. Published online 2014 May 23. doi: 10.1371/journal.pone.0098182

PMCID:: PMC4032286

Abstract Article PDF–512K

Select item 399057712.

The CpG Island Encompassing the Promoter and First Exon of Human DNMT3L Gene Is a PcG/TrX Response Element (PRE)

Amitava Basu, Vasanthi Dasari, Rakesh K. Mishra, Sanjeev Khosla

PLoS One. 2014; 9(4): e93561. Published online 2014 Apr 17. doi: 10.1371/journal.pone.0093561

Correction in:: PLoS One. 2014; 9(8): e105714.

PMCID:: PMC3990577

Abstract Article PDF–2.3M

Select item 293652813.

DNMT3L Modulates Significant and Distinct Flanking Sequence Preference for DNA Methylation by DNMT3A and DNMT3B In Vivo

Bethany L. Wienholz, Michael S. Kareta, Amir H. Moarefi, Catherine A. Gordon, Paul A. Ginno, Frédéric Chédin

PLoS Genet. 2010 Sep; 6(9): e1001106. Published online 2010 Sep 9. doi: 10.1371/journal.pgen.1001106

PMCID:: PMC2936528

Abstract Article PDF–1.4M

Select item 16613314.

Interactions within the mammalian DNA methyltransferase family

Jean B Margot, Ann E Ehrenhofer-Murray, Heinrich Leonhardt

BMC Mol Biol. 2003; 4: 7. Published online 2003 May 30. doi: 10.1186/1471-2199-4-7

PMCID:: PMC166133

Abstract Article PDF–370K

Select item 289251415.

Human Intelligence and Polymorphisms in the DNA Methyltransferase Genes Involved in Epigenetic Marking

Paul Haggarty, Gwen Hoad, Sarah E. Harris, John M. Starr, Helen C. Fox, Ian J. Deary, Lawrence J. Whalley

PLoS One. 2010; 5(6): e11329. Published online 2010 Jun 25. doi: 10.1371/journal.pone.0011329

PMCID:: PMC2892514

Abstract Article PDF–145K

Select item 271283016.

Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation

Da Jia, Renata Z. Jurkowska, Xing Zhang, Albert Jeltsch, Xiaodong Cheng

Nature. Author manuscript; available in PMC 2009 Jul 20.

Published in final edited form as: Nature. 2007 Sep 13; 449(7159): 248–251. Published online 2007 Aug 22. doi: 10.1038/nature06146

PMCID:: PMC2712830

Abstract Article PDF–1017K

Select item 13743117.

Dnmt3L is a transcriptional repressor that recruits histone deacetylase

Rachel Deplus, Carmen Brenner, Wendy A. Burgers, Pascale Putmans, Tony Kouzarides, Yvan de Launoit, François Fuks

Nucleic Acids Res. 2002 Sep 1; 30(17): 3831–3838. doi: 10.1093/nar/gkf509

PMCID:: PMC137431

Abstract Article PDF–427K

Select item 265082018.

DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA

Steen K. T. Ooi, Chen Qiu, Emily Bernstein, Keqin Li, Da Jia, Zhe Yang, Hediye Erdjument-Bromage, Paul Tempst, Shau-Ping Lin, C. David Allis, Xiaodong Cheng, Timothy H. Bestor

Nature. Author manuscript; available in PMC 2009 Mar 4.

Published in final edited form as: Nature. 2007 Aug 9; 448(7154): 714–717. doi: 10.1038/nature05987

PMCID:: PMC2650820

Abstract Article PDF–1.2M

Select item 753464119.

Temporal activation of LRH‐1 and RAR‐γ in human pluripotent stem cells induces a functional naïve‐like state

Adeleh Taei, Tahereh Kiani, Zeinab Taghizadeh, Sharif Moradi, Azam Samadian, Sepideh Mollamohammadi, Ali Sharifi‐Zarchi, Stefan Guenther, Azimeh Akhlaghpour, Behrouz Asgari Abibeiglou, Mostafa Najar‐Asl, Razieh Karamzadeh, Keynoosh Khalooghi, Thomas Braun, Seyedeh‐Nafiseh Hassani, Hossein Baharvand

EMBO Rep. 2020 Oct 5; 21(10): e47533. Published online 2020 Aug 16. doi: 10.15252/embr.201847533

PMCID:: PMC7534641

Abstract Article PDF–4.8M

Select item 152672820.

Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins

Yu-Hui Hu, Hans-Jörg Warnatz, Dominique Vanhecke, Florian Wagner, Andrea Fiebitz, Sabine Thamm, Pascal Kahlem, Hans Lehrach, Marie-Laure Yaspo, Michal Janitz

BMC Genomics. 2006; 7: 155. Published online 2006 Jun 16. doi: 10.1186/1471-2164-7-155