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Select item 109971271.

Hydrostatic pressure mediates epithelial-mesenchymal transition of cholangiocytes through RhoA/ROCK and TGF-β/smad pathways

Mahmoud Osman Khalifa, Chen Yan, Yong Chai, Kosei Ito, Shou-Hua Zhang, Tao-Sheng Li

PLoS One. 2024; 19(4): e0300548. Published online 2024 Apr 5. doi: 10.1371/journal.pone.0300548

PMCID:: PMC10997127

Abstract Article PDF–1.7M

Select item 103988752.

High extracellular glucose promotes cell motility by modulating cell deformability and contractility via the cAMP-RhoA-ROCK axis in human breast cancer cells

Mijung Oh, Skylar Batty, Nayan Banerjee, Tae-Hyung Kim

Mol Biol Cell. 2023 Jul 1; 34(8): ar79. Published online 2023 Jul 1. doi: 10.1091/mbc.E22-12-0560

PMCID:: PMC10398875

Abstract Article PDF–7.7M

Select item 98283893.

LINC00891 regulated by miR-128-3p/GATA2 axis impedes lung cancer cell proliferation, invasion and EMT by inhibiting RhoA pathway: LINC00891 impedes lung cancer progression

Yunfeng Zhang, Dingli Song, Ziyang Peng, Rui Wang, Kai Li, Hong Ren, Xin Sun, Ning Du, Shou-Ching Tang

Acta Biochim Biophys Sin (Shanghai) 2022 Mar; 54(3): 378–387. Published online 2022 Mar 3. doi: 10.3724/abbs.2022005

PMCID:: PMC9828389

Abstract Article PDF–7.1M

Select item 95593284.

RHOA G17V induces T follicular helper cell specification and involves angioimmunoblastic T-cell lymphoma via upregulating the expression of PON2 through an NF-κB-dependent mechanism

Fenglian Que, Lihong Zhang, Taoli Wang, Meifang Xu, Wangen Li, Shengbing Zang

Oncoimmunology. 2022; 11(1): 2134536. Published online 2022 Oct 11. doi: 10.1080/2162402X.2022.2134536

PMCID:: PMC9559328

Abstract Article PDF–14M

Select item 87147075.

Spatial and temporal dynamics of RhoA activities of single breast tumor cells in a 3D environment revealed by a machine learning-assisted FRET technique

Brian CH Cheung, Louis Hodgson, Jeffrey E Segall, Mingming Wu

Exp Cell Res. Author manuscript; available in PMC 2023 Jan 15.

Published in final edited form as: Exp Cell Res. 2022 Jan 15; 410(2): 112939. Published online 2021 Nov 20. doi: 10.1016/j.yexcr.2021.112939

PMCID:: PMC8714707

Abstract Article PDF–1.5M

Select item 85088246.

N6-Isopentenyladenosine Hinders the Vasculogenic Mimicry in Human Glioblastoma Cells through Src-120 Catenin Pathway Modulation and RhoA Activity Inhibition

Cristina Pagano, Giovanna Navarra, Olga Pastorino, Giorgio Avilia, Laura Coppola, Rosa Della Monica, Lorenzo Chiariotti, Tullio Florio, Alessandro Corsaro, Giovanni Torelli, Pasquale Caiazzo, Patrizia Gazzerro, Maurizio Bifulco, Chiara Laezza

Int J Mol Sci. 2021 Oct; 22(19): 10530. Published online 2021 Sep 29. doi: 10.3390/ijms221910530

PMCID:: PMC8508824

Abstract Article PDF–4.6M

Select item 84081467.

The RhoA dependent anti-metastatic function of RKIP in breast cancer

Gardiyawasam Kalpana, Christopher Figy, Jingwei Feng, Claire Tipton, Julius N. De Castro, Vu N. Bach, Clariza Borile, Alexandria LaSalla, Hussain N. Odeh, Miranda Yeung, Rafael Garcia-Mata, Kam C. Yeung

Sci Rep. 2021; 11: 17455. Published online 2021 Aug 31. doi: 10.1038/s41598-021-96709-6

Correction in:: Sci Rep. 2023; 13: 11293.

PMCID:: PMC8408146

Abstract Article PDF–3.1M

Select item 82924768.

High-throughput sequencing identified circular RNA circUBE2K mediating RhoA associated bladder cancer phenotype via regulation of miR-516b-5p/ARHGAP5 axis

Chen Yang, Zezhong Mou, Siqi Wu, Yuxi Ou, Zheyu Zhang, Xinan Chen, Xiyu Dai, Chenyang Xu, Shanhua Mao, Haowen Jiang

Cell Death Dis. 2021 Aug; 12(8): 719. Published online 2021 Jul 20. doi: 10.1038/s41419-021-03977-1

Correction in:: Cell Death Dis. 2022 Dec; 13(12): 1066.

PMCID:: PMC8292476

Abstract Article PDF–6.6M

Select item 81781639.

Structure of an inactive conformation of GTP-bound RhoA GTPase

Yuan Lin, Shaoyong Lu, Jian Zhang, Yi Zheng

Structure. Author manuscript; available in PMC 2022 Jun 3.

Published in final edited form as: Structure. 2021 Jun 3; 29(6): 553–563.e5. Published online 2021 Jan 25. doi: 10.1016/j.str.2020.12.015

PMCID:: PMC8178163

Abstract Article PDF–1.8M

Select item 810146010.

Myosin II and Arp2/3 cross-talk governs intracellular hydraulic pressure and lamellipodia formation

Shivani Patel, Donna McKeon, Kimheak Sao, Changsong Yang, Nicole M. Naranjo, Tatyana M. Svitkina, Ryan J. Petrie

Mol Biol Cell. 2021 Apr 1; 32(7): 579–589. doi: 10.1091/mbc.E20-04-0227

PMCID:: PMC8101460

Abstract Article PDF–2.8M

Select item 809226011.

Human Cytomegalovirus miR-US25-1 Targets the GTPase RhoA To Inhibit CD34⁺ Hematopoietic Progenitor Cell Proliferation To Maintain the Latent Viral Genome

Nicole L. Diggins, Lindsey B. Crawford, Meaghan H. Hancock, Jennifer Mitchell, Jay A. Nelson

mBio. 2021 Mar-Apr; 12(2): e00621-21. Published online 2021 Apr 6. doi: 10.1128/mBio.00621-21

PMCID:: PMC8092260

Abstract Article PDF–2.4M

Select item 804422512.

EpCAM promotes endosomal modulation of the cortical RhoA zone for epithelial organization

Cécile Gaston, Simon De Beco, Bryant Doss, Meng Pan, Estelle Gauquelin, Joseph D’Alessandro, Chwee Teck Lim, Benoit Ladoux, Delphine Delacour

Nat Commun. 2021; 12: 2226. Published online 2021 Apr 13. doi: 10.1038/s41467-021-22482-9

PMCID:: PMC8044225

Abstract Article PDF–9.5M

Select item 794910313.

Optogenetic control of small GTPases reveals RhoA mediates intracellular calcium signaling

Hironori Inaba, Qianqian Miao, Takao Nakata

J Biol Chem. 2021 Jan-Jun; 296: 100290. Published online 2021 Jan 13. doi: 10.1016/j.jbc.2021.100290

PMCID:: PMC7949103

Abstract Article PDF–4.0M

Select item 779623114.

Role of Macrophages and RhoA Pathway in Atherosclerosis

Malgorzata Kloc, Ahmed Uosef, Jacek Z. Kubiak, Rafik Mark Ghobrial

Int J Mol Sci. 2021 Jan; 22(1): 216. Published online 2020 Dec 28. doi: 10.3390/ijms22010216

PMCID:: PMC7796231

Abstract Article PDF–2.6M

Select item 744731115.

A comprehensive analysis of RHOA mutation positive and negative angioimmunoblastic T-cell lymphomas by targeted deep sequencing, expression profiling and single cell digital image analysis

Alexandra Butzmann, Kaushik Sridhar, Diwash Jangam, Jyoti Kumar, Malaya Kumar Sahoo, Nahid Shahmarvand, Roger Warnke, Elumalai Rangasamy, Benjamin Alan Pinsky, Robert Shigeo Ohgami

Int J Mol Med. 2020 Oct; 46(4): 1466–1476. Published online 2020 Jul 28. doi: 10.3892/ijmm.2020.4686

PMCID:: PMC7447311

Abstract Article PDF–1.0M

Select item 728409716.

Multiple mutations at exon 2 of RHOA detected in plasma from patients with peripheral T-cell lymphoma

Barbara Ottolini, Nadia Nawaz, Christopher S. Trethewey, Sami Mamand, Rebecca L. Allchin, Richard Dillon, Paul A. Fields, Matthew J. Ahearne, Simon D. Wagner

Blood Adv. 2020 Jun 9; 4(11): 2392–2403. Published online 2020 Jun 2. doi: 10.1182/bloodadvances.2019001075

PMCID:: PMC7284097

Abstract Article PDF–1.6M

Select item 724607617.

Impact of RhoA overexpression on clinical outcomes in cervical squamous cell carcinoma treated with concurrent chemoradiotherapy

Keiichi Tanaka, Yoshitaka Matsumoto, Hitoshi Ishikawa, Nobuyoshi Fukumitsu, Haruko Numajiri, Keiko Murofushi, Yoshiko Oshiro, Toshiyuki Okumura, Toyomi Satoh, Hideyuki Sakurai

J Radiat Res. 2020 Mar; 61(2): 221–230. Published online 2020 Jan 24. doi: 10.1093/jrr/rrz093

PMCID:: PMC7246076

Abstract Article PDF–483K

Select item 689107518.

Confinement hinders motility by inducing RhoA-mediated nuclear influx, volume expansion, and blebbing

Panagiotis Mistriotis, Emily O. Wisniewski, Kaustav Bera, Jeremy Keys, Yizeng Li, Soontorn Tuntithavornwat, Robert A. Law, Nicolas A. Perez-Gonzalez, Eda Erdogmus, Yuqi Zhang, Runchen Zhao, Sean X. Sun, Petr Kalab, Jan Lammerding, Konstantinos Konstantopoulos

J Cell Biol. 2019 Dec 2; 218(12): 4093–4111. Published online 2019 Nov 5. doi: 10.1083/jcb.201902057

PMCID:: PMC6891075

Abstract Article PDF–2.7M

Select item 677581619.

In vivo effects of mutant RHOA on tumor formation in an orthotopic inoculation model

Takashi Nishizawa, Kiyotaka Nakano, Etsuko Fujii, Daisuke Komura, Yoshie Kuroiwa, Chisako Ishimaru, Makoto Monnai, Hiroyuki Aburatani, Shumpei Ishikawa, Masami Suzuki

Oncol Rep. 2019 Nov; 42(5): 1745–1754. Published online 2019 Sep 3. doi: 10.3892/or.2019.7300

PMCID:: PMC6775816

Abstract Article PDF–1.1M

Select item 668251520.

The diagnostic and prognostic role of RhoA in hepatocellular carcinoma

Yi Bai, Fucun Xie, Fei Miao, Junyu Long, Shan Huang, Hanchun Huang, Jianzhen Lin, Dongxu Wang, Xu Yang, Jin Bian, Jinzhu Mao, Xi Wang, Yilei Mao, Xinting Sang, Haitao Zhao

Aging (Albany NY) 2019 Jul 31; 11(14): 5158–5172. Published online 2019 Jul 22. doi: 10.18632/aging.102110