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Items: 1 to 20 of 28

1.
Increased THEMIS First Exon Usage in CD4+ T-Cells Is Associated with a Genotype that Is Protective against Multiple Sclerosis
Jessica L. Davies, Sara Thompson, Harpreet Kaur-Sandhu, Stephen Sawcer, Alasdair Coles, Maria Ban, Joanne Jones
PLoS One. 2016; 11(7): e0158327. Published online 2016 Jul 20. doi: 10.1371/journal.pone.0158327
PMCID:
PMC4954697
AbstractArticlePDF–907K
2.
Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer
Christopher E. Barbieri, Sylvan C. Baca, Michael S. Lawrence, Francesca Demichelis, Mirjam Blattner, Jean-Philippe Theurillat, Thomas A. White, Petar Stojanov, Eliezer Van Allen, Nicolas Stransky, Elizabeth Nickerson, Sung-Suk Chae, Gunther Boysen, Daniel Auclair, Robert Onofrio, Kyung Park, Naoki Kitabayashi, Theresa Y. MacDonald, Karen Sheikh, Terry Vuong, Candace Guiducci, Kristian Cibulskis, Andrey Sivachenko, Scott L. Carter, Gordon Saksena, Douglas Voet, Wasay M. Hussain, Alex H. Ramos, Wendy Winckler, Michelle C. Redman, Kristin Ardlie, Ashutosh K. Tewari, Juan Miguel Mosquera, Niels Rupp, Peter J. Wild, Holger Moch, Colm Morrissey, Peter S. Nelson, Philip W. Kantoff, Stacey B. Gabriel, Todd R. Golub, Matthew Meyerson, Eric S. Lander, Gad Getz, Mark A. Rubin, Levi A. Garraway
Nat Genet. Author manuscript; available in PMC 2013 Jun 5.
Published in final edited form as: Nat Genet. 2012 May 20; 44(6): 685–689. Published online 2012 May 20. doi: 10.1038/ng.2279
PMCID:
PMC3673022
AbstractArticlePDF–2.3M
3.
THEMIS and PTPRK in celiac intestinal mucosa: coexpression in disease and after in vitro gliadin challenge
Constanza Bondar, Leticia Plaza-Izurieta, Nora Fernandez-Jimenez, Iñaki Irastorza, Sebo Withoff, CEGEC, Cisca Wijmenga, Fernando Chirdo, Jose Ramon Bilbao
Eur J Hum Genet. 2014 Mar; 22(3): 358–362. Published online 2013 Jul 3. doi: 10.1038/ejhg.2013.136
PMCID:
PMC3925264
AbstractArticlePDF–579K
4.
Themis sets the signal threshold for positive and negative selection in T-cell development
Guo Fu, Javier Casas, Stephanie Rigaud, Vasily Rybakin, Florence Lambolez, Joanna Brzostek, John A.H. Hoerter, Wolfgang Paster, Oreste Acuto, Hilde Cheroutre, Karsten Sauer, Nicholas R.J. Gascoigne
Nature. Author manuscript; available in PMC 2014 Jun 19.
Published in final edited form as: Nature. 2013 Dec 19; 504(7480): 441–445. Published online 2013 Nov 13. doi: 10.1038/nature12718
PMCID:
PMC3977001
ArticlePDF–5.4M
5.
T Cell Receptor (TCR)-induced Tyrosine Phosphorylation Dynamics Identifies THEMIS as a New TCR Signalosome Component
Claudia Brockmeyer, Wolfgang Paster, David Pepper, Choon P. Tan, David C. Trudgian, Simon McGowan, Guo Fu, Nicholas R. J. Gascoigne, Oreste Acuto, Mogjiborahman Salek
J Biol Chem. 2011 Mar 4; 286(9): 7535–7547. Published online 2010 Dec 28. doi: 10.1074/jbc.M110.201236
PMCID:
PMC3045008
AbstractArticlePDF–2.6M
6.
A Novel Gene Essential for the Development of Single Positive Thymocytes
Kiyokazu Kakugawa , Takuwa Yasuda, Ikuo Miura, Ayako Kobayashi, Hitomi Fukiage, Rumi Satoh, Masashi Matsuda, Haruhiko Koseki, Shigeharu Wakana, Hiroshi Kawamoto, Hisahiro Yoshida
Mol Cell Biol. 2009 Sep; 29(18): 5128–5135. Published online 2009 Jul 20. doi: 10.1128/MCB.00793-09
PMCID:
PMC2738282
AbstractArticlePDF–6.6M
7.
THEMIS-SHP1 Recruitment by 4–1BB Tunes LCK-Mediated Priming of Chimeric Antigen Receptor-Redirected T Cells
Chuang Sun, Peishun Shou, Hongwei Du, Koichi Hirabayashi, Yuhui Chen, Laura E. Herring, Sarah Ahn, Yang Xu, Kyogo Suzuki, Guangming Li, Ourania Tsahouridis, Lishan Su, Barbara Savoldo, Gianpietro Dotti
Cancer Cell. Author manuscript; available in PMC 2021 Feb 10.
Published in final edited form as: Cancer Cell. 2020 Feb 10; 37(2): 216–225.e6. Published online 2020 Jan 30. doi: 10.1016/j.ccell.2019.12.014
PMCID:
PMC7397569
AbstractArticlePDF–2.6M
8.
HTLV-1 bZIP Factor Enhances T-Cell Proliferation by Impeding the Suppressive Signaling of Co-inhibitory Receptors
Haruka Kinosada, Jun-ichirou Yasunaga, Kazuya Shimura, Paola Miyazato, Chiho Onishi, Tomonori Iyoda, Kayo Inaba, Masao Matsuoka
PLoS Pathog. 2017 Jan; 13(1): e1006120. Published online 2017 Jan 3. doi: 10.1371/journal.ppat.1006120
Correction in:
PLoS Pathog. 2017 Feb; 13(2): e1006228.
PMCID:
PMC5234849
AbstractArticlePDF–5.6M
9.
Gasp, a Grb2-associating protein, is critical for positive selection of thymocytes
Michael S. Patrick, Hiroyo Oda, Kunihiro Hayakawa, Yoshinori Sato, Koji Eshima, Teruo Kirikae, Shun-ichiro Iemura, Mutsunori Shirai, Takaya Abe, Tohru Natsume, Takehiko Sasazuki, Harumi Suzuki
Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16345–16350. Published online 2009 Sep 14. doi: 10.1073/pnas.0908593106
PMCID:
PMC2752560
AbstractArticlePDF–1.3M
10.
THEMIS enhances TCR signaling and enables positive selection by selective inhibition of SHP-1
Seeyoung Choi, Claude Warzecha, Ekaterina Zvezdova, Jan Lee, Jérémy Argenty, Renaud Lesourne, L. Aravind, Paul E. Love
Nat Immunol. Author manuscript; available in PMC 2018 Feb 9.
Published in final edited form as: Nat Immunol. 2017 Apr; 18(4): 433–441. Published online 2017 Feb 27. doi: 10.1038/ni.3692
PMCID:
PMC5807080
AbstractArticlePDF–1.1M
11.
A THEMIS:SHP1 complex promotes T-cell survival
Wolfgang Paster, Annika M Bruger, Kristin Katsch, Claude Grégoire, Romain Roncagalli, Guo Fu, Nicholas RJ Gascoigne, Konstantina Nika, Andre Cohnen, Stephan M Feller, Philip C Simister, Kelly C Molder, Shaun-Paul Cordoba, Omer Dushek, Bernard Malissen, Oreste Acuto
EMBO J. 2015 Feb 3; 34(3): 393–409. Published online 2014 Dec 22. doi: 10.15252/embj.201387725
PMCID:
PMC4339124
AbstractArticlePDF–1.3M
12.
GRB2-Mediated Recruitment of THEMIS to LAT Is Essential for Thymocyte Development
Wolfgang Paster, Claudia Brockmeyer, Guo Fu, Philip C. Simister, Ben de Wet, Ana Martinez-Riaño, John A. H. Hoerter, Stephan M. Feller, Christoph Wülfing, Nicholas R. J. Gascoigne, Oreste Acuto
J Immunol. 2013 Apr 1; 190(7): 3749–3756. Published online 2013 Mar 4. doi: 10.4049/jimmunol.1203389
PMCID:
PMC3607403
AbstractArticlePDF–1.9M
13.
Themis is a member of a new metazoan gene family and is required for completion of thymocyte positive selection
Andy L. Johnson, L. Aravind, Natalia Shulzhenko, Andriy Morgun, See-Young Choi, Tanya L. Crockford, Teresa Lambe, Heather Domaschenz, Edyta Kucharska, Lixin Zheng, Carola C. Vinuesa, Michael J. Lenardo, Christopher C. Goodnow, Richard J. Cornall, Ronald H. Schwartz
Nat Immunol. Author manuscript; available in PMC 2010 Jul 23.
Published in final edited form as: Nat Immunol. 2009 Aug; 10(8): 831–839. Published online 2009 Jul 13. doi: 10.1038/ni.1769
Correction in:
volume 11 on page 97
PMCID:
PMC2908989
AbstractArticlePDF–1.4M
14.
THEMIS, a new T cell specific protein important for late thymocyte development
Renaud Lesourne, Shoji Uehara, Jan Lee, Ki-Duk Song, LiQi Li, Julia Pinkhasov, Yongqing Zhang, Nan-Ping Weng, Kathryn F. Wildt, Lie Wang, Remy Bosselut, Paul E. Love
Nat Immunol. Author manuscript; available in PMC 2010 Apr 1.
Published in final edited form as: Nat Immunol. 2009 Aug; 10(8): 840–847. Published online 2009 Jul 13. doi: 10.1038/ni.1768
Correction in:
volume 11 on page 97
PMCID:
PMC2848698
AbstractArticlePDF–2.2M
15.
Themis controls thymocyte selection through regulation of T cell receptor-mediated signaling
Guo Fu, Sébastien Vallée, Vasily Rybakin, Marielena V. McGuire, Jeanette Ampudia, Claudia Brockmeyer, Mogjiborahman Salek, Paul R. Fallen, John A.H. Hoerter, Anil Munshi, Yina H. Huang, Jianfang Hu, Howard S. Fox, Karsten Sauer, Oreste Acuto, Nicholas R.J. Gascoigne
Nat Immunol. Author manuscript; available in PMC 2010 Feb 1.
Published in final edited form as: Nat Immunol. 2009 Aug; 10(8): 848–856. Published online 2009 Jul 13. doi: 10.1038/ni.1766
PMCID:
PMC2757056
AbstractArticlePDF–2.8M
16.
Novel breast cancer risk alleles and interaction with ionizing radiation among U.S. Radiologic Technologists
Parveen Bhatti, Michele M. Doody, Preetha Rajaraman, Bruce H. Alexander, Meredith Yeager, Amy Hutchinson, Laurie Burdette, Gilles Thomas, David J. Hunter, Steven L. Simon, Robert M. Weinstock, Marvin Rosenstein, Marilyn Stovall, Dale L. Preston, Martha S. Linet, Robert N. Hoover, Stephen J. Chanock, Alice J. Sigurdson
Radiat Res. Author manuscript; available in PMC 2011 Feb 1.
Published in final edited form as: Radiat Res. 2010 Feb; 173(2): 214–224. doi: 10.1667/RR1985.1
PMCID:
PMC2922870
AbstractArticlePDF–345K
17.
Generalization of Variants Identified by Genome-wide Association Studies for Electrocardiographic Traits in African Americans
Janina M. Jeff, Marylyn D. Ritchie, Joshua C. Denny, Abel N. Kho, Andrea H. Ramirez, David Crosslin, Loren Armstrong, Melissa A. Basford, Wendy A. Wolf, Jennifer A. Pacheco, Rex L. Chisholm, Dan M. Roden, M. Geoffrey Hayes, Dana C. Crawford
Ann Hum Genet. Author manuscript; available in PMC 2014 Jul 30.
Published in final edited form as: Ann Hum Genet. 2013 Jul; 77(4): 321–332. Published online 2013 Mar 28. doi: 10.1111/ahg.12023
PMCID:
PMC3743946
AbstractArticlePDF–375K
18.
Interchangeability of Themis1 and Themis2 in thymocyte development reveals two related proteins with conserved molecular function
Renaud Lesourne, Ekaterina Zvezdova, Ki-Duk Song, Dalal El-Khoury, Shoji Uehara, Valarie A. Barr, Lawrence E. Samelson, Paul E. Love
J Immunol. Author manuscript; available in PMC 2013 Aug 1.
Published in final edited form as: J Immunol. 2012 Aug 1; 189(3): 1154–1161. Published online 2012 Jun 25. doi: 10.4049/jimmunol.1200123
PMCID:
PMC3401357
AbstractArticlePDF–1.3M
19.
Multiple common variants for celiac disease influencing immune gene expression
Patrick CA Dubois, Gosia Trynka, Lude Franke, Karen A Hunt, Jihane Romanos, Alessandra Curtotti, Alexandra Zhernakova, Graham AR Heap, Róza Ádány, Arpo Aromaa, Maria Teresa Bardella, Leonard H van den Berg, Nicholas A Bockett, Emilio G. de la Concha, Bárbara Dema, Rudolf SN Fehrmann, Miguel Fernández-Arquero, Szilvia Fiatal, Elvira Grandone, Peter M Green, Harry JM Groen, Rhian Gwilliam, Roderick HJ Houwen, Sarah E Hunt, Katri Kaukinen, Dermot Kelleher, Ilma Korponay-Szabo, Kalle Kurppa, Padraic MacMathuna, Markku Mäki, Maria Cristina Mazzilli, Owen T McCann, M Luisa Mearin, Charles A Mein, Muddassar M Mirza, Vanisha Mistry, Barbara Mora, Katherine I Morley, Chris J Mulder, Joseph A Murray, Concepción Núñez, Elvira Oosterom, Roel A Ophoff, Isabel Polanco, Leena Peltonen, Mathieu Platteel, Anna Rybak, Veikko Salomaa, Joachim J Schweizer, Maria Pia Sperandeo, Greetje J Tack, Graham Turner, Jan H Veldink, Wieke HM Verbeek, Rinse K Weersma, Victorien M Wolters, Elena Urcelay, Bozena Cukrowska, Luigi Greco, Susan L. Neuhausen, Ross McManus, Donatella Barisani, Panos Deloukas, Jeffrey C Barrett, Paivi Saavalainen, Cisca Wijmenga, David A van Heel
Nat Genet. Author manuscript; available in PMC 2010 Oct 1.
Published in final edited form as: Nat Genet. 2010 Apr; 42(4): 295–302. Published online 2010 Feb 28. doi: 10.1038/ng.543
Correction in:
volume 42 on page 465
PMCID:
PMC2847618
AbstractArticlePDF–1.0M
20.
Genome-Wide Analysis of Polymorphisms Associated with Cytokine Responses in Smallpox Vaccine Recipients
Richard B. Kennedy, Inna G. Ovsyannikova, V. Shane Pankratz, Iana H. Haralambieva, Robert A. Vierkant, Gregory A. Poland
Hum Genet. Author manuscript; available in PMC 2014 Sep 22.
Published in final edited form as: Hum Genet. 2012 Sep; 131(9): 1403–1421. Published online 2012 May 19. doi: 10.1007/s00439-012-1174-2
PMCID:
PMC4170585
AbstractArticlePDF–594K

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