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Select item 108525821.

The Plasminogen Activator Inhibitor 1 4G/5G Polymorphism and the Risk of Alzheimer’s Disease

Najiba Fekih-Mrissa, Malek Mansour, Aicha Sayeh, Ines Bedoui, Meriem Mrad, Anis Riahi, Ridha Mrissa, Brahim Nsiri

Am J Alzheimers Dis Other Demen. 2017 Sep; 32(6): 342–346. Published online 2017 May 3. doi: 10.1177/1533317517705223

PMCID:: PMC10852582

Abstract Article PDF–132K

Select item 108283102.

Higher testosterone and testosterone/estradiol ratio in men are associated with decreased Pheno-/GrimAge and DNA-methylation based PAI1

Cynthia D. J. Kusters, Kimberly C. Paul, Ake T. Lu, Luigi Ferruci, Beate R. Ritz, Alexandra M. Binder, Steve Horvath

GeroScience. 2024 Feb; 46(1): 1053–1069. Published online 2023 Jun 27. doi: 10.1007/s11357-023-00832-3

Correction in:: GeroScience. 2024 Apr; 46(2): 2791–2792.

PMCID:: PMC10828310

Abstract Article PDF–1.7M

Select item 107020743.

Spontaneous miscarriage driven by maternal genetic mutation at position of PAI-1-844G/A: shed light on a race-specific genetic polymorphism

Afrah Ameri, Khalil Khashei Varnamkhasti, Sara Parhoudeh, Samire Khashei Varnamkhasti, Leila Naeimi, Sirous Naeimi

BMC Res Notes. 2023; 16: 360. Published online 2023 Dec 6. doi: 10.1186/s13104-023-06635-1

PMCID:: PMC10702074

Abstract Article PDF–1.6M

Select item 105973874.

Serum plasminogen activator inhibitor-1 levels in patients with major depressive disorder vs. healthy controls: a systematic review and meta-analysis

Mohamed Elsayed, Khaled A. Mohamed, Khaled T. Dardeer, Dalia K. Zaafar, Soha Osama Hassanin, Ramy Abdelnaby, Carlos Schönfeldt-Lecuona

Trends Psychiatry Psychother. 2023; 45: e20230338. Published online 2023 Aug 4. doi: 10.47626/2237-6089-2021-0338

PMCID:: PMC10597387

Abstract Article PDF–856K

Select item 105334935.

Serpin E1 mediates the induction of renal tubular degeneration and premature senescence upon diabetic insult

Bo Han Chen, Xiao Qing Lu, Xian Hui Liang, Pei Wang

Sci Rep. 2023; 13: 16210. Published online 2023 Sep 27. doi: 10.1038/s41598-023-43411-4

PMCID:: PMC10533493

Abstract Article PDF–5.7M

Select item 104315906.

PAI-1 genetic polymorphisms influence septic patients' outcomes by regulating neutrophil activity

Shaowei Jiang, Yang Wang, Liang Chen, Honghua Mu, Connor Meaney, Yiwen Fan, Janesh Pillay, Hairong Wang, Jincheng Zhang, Shuming Pan, Chengjin Gao

Chin Med J (Engl) 2023 Aug 20; 136(16): 1959–1966. Published online 2023 Jul 13. doi: 10.1097/CM9.0000000000002316

PMCID:: PMC10431590

Abstract Article PDF–550K

Select item 104231627.

Leiran Feng, Guixin Li, Dongbin Li, Guoqiang Duan, Jin Liu

J Cancer Res Clin Oncol. 2023; 149(12): 10851–10865. Published online 2023 Jun 15. doi: 10.1007/s00432-023-04900-1

PMCID:: PMC10423162

Abstract Article PDF–4.9M

Select item 103241448.

Cancer-associated fibroblast-derived PAI-1 promotes lymphatic metastasis via the induction of EndoMT in lymphatic endothelial cells

Wen-Fei Wei, Hui-Ling Zhou, Pei-Yu Chen, Xiao-Lan Huang, Long Huang, Luo-Jiao Liang, Chu-Hong Guo, Chen-Fei Zhou, Lan Yu, Liang-Sheng Fan, Wei Wang

J Exp Clin Cancer Res. 2023; 42: 160. Published online 2023 Jul 6. doi: 10.1186/s13046-023-02714-0

PMCID:: PMC10324144

Abstract Article PDF–12M

Select item 102165229.

PAI-1 Overexpression in Valvular Interstitial Cells Contributes to Hypofibrinolysis in Aortic Stenosis

Magdalena Kopytek, Michał Ząbczyk, Piotr Mazur, Anetta Undas, Joanna Natorska

Cells. 2023 May; 12(10): 1402. Published online 2023 May 16. doi: 10.3390/cells12101402

PMCID:: PMC10216522

Abstract Article PDF–2.4M

Select item 1017874510.

Association between PAI-1 Polymorphisms and Ischemic Stroke in a South Korean Case-Control Cohort

Gun Ho Choi, Sung Hwan Cho, Hui Jeong An, Han Sung Park, Jeong Yong Lee, Eun Ju Ko, Seung Hun Oh, Ok Joon Kim, Nam Keun Kim

Int J Mol Sci. 2023 May; 24(9): 8041. Published online 2023 Apr 28. doi: 10.3390/ijms24098041

PMCID:: PMC10178745

Abstract Article PDF–993K

Select item 1004952411.

The Role of Plasminogen Activator Inhibitor 1 in Predicting Sepsis-Associated Liver Dysfunction: An Observational Study

Ewa Woźnica-Niesobska, Patrycja Leśnik, Jarosław Janc, Małgorzata Zalewska, Lidia Łysenko

Int J Environ Res Public Health. 2023 Mar; 20(6): 4846. Published online 2023 Mar 9. doi: 10.3390/ijerph20064846

PMCID:: PMC10049524

Abstract Article PDF–1.5M

Select item 1003747012.

The Biological Role of Pleural Fluid PAI-1 and Sonographic Septations in Pleural Infection: Analysis of a Prospectively Collected Clinical Outcome Study

Eihab O. Bedawi, Nikolaos I. Kanellakis, John P. Corcoran, Yu Zhao, Maged Hassan, Rachelle Asciak, Rachel M. Mercer, Anand Sundaralingam, Dinesh N. Addala, Robert F. Miller, Tao Dong, Alison M. Condliffe, Najib M. Rahman

Am J Respir Crit Care Med. 2023 Mar 15; 207(6): 731–739. Published online 2022 Oct 3. doi: 10.1164/rccm.202206-1084OC

PMCID:: PMC10037470

Abstract Article PDF–746K

Select item 1000363013.

Association of SNPs in the PAI1 Gene with Disease Recurrence and Clinical Outcome in Bladder Cancer

Kaoru Murakami, Hideki Furuya, Kanani Hokutan, Steve Goodison, Ian Pagano, Runpu Chen, Cheng-Huang Shen, Michael W. Y. Chan, Chi Fai Ng, Takashi Kobayashi, Osamu Ogawa, Makito Miyake, Mark Thornquist, Yoshiko Shimizu, Kazukuni Hayashi, Zhangwei Wang, Herbert Yu, Charles J. Rosser

Int J Mol Sci. 2023 Mar; 24(5): 4943. Published online 2023 Mar 3. doi: 10.3390/ijms24054943

PMCID:: PMC10003630

Abstract Article PDF–8.2M

Select item 990688514.

The expression of SERPINE1 in colon cancer and its regulatory network and prognostic value

Yigang Wang, Jinyan Wang, Jianchao Gao, Mei Ding, Hua Li

BMC Gastroenterol. 2023; 23: 33. Published online 2023 Feb 8. doi: 10.1186/s12876-022-02625-y

PMCID:: PMC9906885

Abstract Article PDF–4.4M

Select item 987692515.

Data mining combines bioinformatics discover immunoinfiltration-related gene SERPINE1 as a biomarker for diagnosis and prognosis of stomach adenocarcinoma

Yiyan Zhai, Xinkui Liu, Zhihong Huang, Jingyuan Zhang, Antony Stalin, Yingying Tan, Fanqin Zhang, Meilin Chen, Rui Shi, Jiaqi Huang, Chao Wu, Zhishan Wu, Shan Lu, Leiming You, Jiarui Wu

Sci Rep. 2023; 13: 1373. Published online 2023 Jan 25. doi: 10.1038/s41598-023-28234-7

PMCID:: PMC9876925

Abstract Article PDF–8.5M

Select item 966731016.

Deep mutational scanning and massively parallel kinetics of plasminogen activator inhibitor-1 functional stability to probe its latency transition

Laura M. Haynes, Zachary M. Huttinger, Andrew Yee, Colin A. Kretz, David R. Siemieniak, Daniel A. Lawrence, David Ginsburg

J Biol Chem. 2022 Dec; 298(12): 102608. Published online 2022 Oct 17. doi: 10.1016/j.jbc.2022.102608

PMCID:: PMC9667310

Abstract Article PDF–1.2M

Select item 956995617.

SERPINE1 DNA Methylation Levels Quantified in Blood Cells at Five Years of Age Are Associated with Adiposity and Plasma PAI-1 Levels at Five Years of Age

Amelie Taschereau, Véronique Desgagné, Sabrina Faleschini, Renée Guérin, Catherine Allard, Patrice Perron, Marie-France Hivert, Luigi Bouchard

Int J Mol Sci. 2022 Oct; 23(19): 11833. Published online 2022 Oct 5. doi: 10.3390/ijms231911833

PMCID:: PMC9569956

Abstract Article PDF–1.0M

Select item 943275418.

The role of the platelet pool of Plasminogen Activator Inhibitor-1 in well-controlled type 2 diabetes patients

Karin Mossberg, Josefin Olausson, Emanuel Fryk, Sverker Jern, Per-Anders Jansson, Helén Brogren

PLoS One. 2022; 17(8): e0267833. Published online 2022 Aug 31. doi: 10.1371/journal.pone.0267833

PMCID:: PMC9432754

Abstract Article PDF–1.0M

Select item 941824419.

SerpinE1 drives a cell-autonomous pathogenic signaling in Hutchinson–Gilford progeria syndrome

Giorgia Catarinella, Chiara Nicoletti, Andrea Bracaglia, Paola Procopio, Illari Salvatori, Marilena Taggi, Cristiana Valle, Alberto Ferri, Rita Canipari, Pier Lorenzo Puri, Lucia Latella

Cell Death Dis. 2022 Aug; 13(8): 737. Published online 2022 Aug 26. doi: 10.1038/s41419-022-05168-y