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Select item 99642171.

DUOX1 Gene Missense Mutation Confers Susceptibility on Type 2 Amiodarone-Induced Thyrotoxicosis

Olga Biakina, Yulia Mitina, Daria Gognieva, Marina Axenova, Alexandra Ermolaeva, Afina Bestavashvili, Valentin Fadeev, Abram Syrkin, Philipp Kopylov

Int J Mol Sci. 2023 Feb; 24(4): 4016. Published online 2023 Feb 16. doi: 10.3390/ijms24044016

PMCID:: PMC9964217

Abstract Article PDF–250K

Select item 78834042.

Knockdown of Dual Oxidase 1 (DUOX1) Promotes Wound Healing by Regulating Reactive Oxygen Species (ROS) by Activation of Nuclear Factor kappa B (NF-κB) Signaling

Hui Wang, Haowei Lu, Yige Wu

Med Sci Monit. 2021; 27: e926492-1–e926492-11. Prepublished online 2020 Dec 8. Published online 2021 Feb 10. doi: 10.12659/MSM.926492

PMCID:: PMC7883404

Abstract Article PDF–1.5M

Select item 59330113.

DUOX1 Silencing in Mammary Cell Alters the Response to Genotoxic Stress

Rodrigo S. Fortunato, Luciana R. Gomes, Veridiana Munford, Carolina Fittipaldi Pessoa, Annabel Quinet, Fabio Hecht, Gustavo S. Kajitani, Cristiane Bedran Milito, Denise P. Carvalho, Carlos Frederico Martins Menck

Oxid Med Cell Longev. 2018; 2018: 3570526. Published online 2018 Apr 19. doi: 10.1155/2018/3570526

PMCID:: PMC5933011

Abstract Article PDF–2.0M

Select item 59009944.

Dual oxidase: a novel therapeutic target in allergic disease

Albert van der Vliet, Karamatullah Danyal, David E Heppner

Br J Pharmacol. 2018 May; 175(9): 1401–1418. Published online 2018 Mar 15. doi: 10.1111/bph.14158

PMCID:: PMC5900994

Abstract Article PDF–1.4M

Select item 48699385.

Dual oxidase 1: A predictive tool for the prognosis of hepatocellular carcinoma patients

SHENGSEN CHEN, QINGXIA LING, KANGKANG YU, CHONG HUANG, NING LI, JIANMING ZHENG, SUXIA BAO, QI CHENG, MENGQI ZHU, MINGQUAN CHEN

Oncol Rep. 2016 Jun; 35(6): 3198–3208. Published online 2016 Apr 14. doi: 10.3892/or.2016.4745

PMCID:: PMC4869938

Abstract Article PDF–1000K

Select item 44133476.

NADPH oxidase DUOX1 promotes long-term persistence of oxidative stress after an exposure to irradiation

Rabii Ameziane-El-Hassani, Monique Talbot, Maria Carolina de Souza Dos Santos, Abir Al Ghuzlan, Dana Hartl, Jean-Michel Bidart, Xavier De Deken, Françoise Miot, Ibrahima Diallo, Florent de Vathaire, Martin Schlumberger, Corinne Dupuy

Proc Natl Acad Sci U S A. 2015 Apr 21; 112(16): 5051–5056. Published online 2015 Apr 6. doi: 10.1073/pnas.1420707112

PMCID:: PMC4413347

Abstract Article PDF–1.0M

Select item 29412057.

The Nonphagocytic NADPH Oxidase Duox1 Mediates a Positive Feedback Loop During T Cell Receptor Signaling

Jaeyul Kwon, Kristen E. Shatynski, Haiyan Chen, Stanislas Morand, Xavier de Deken, Françoise Miot, Thomas L. Leto, Mark S. Williams

Sci Signal. Author manuscript; available in PMC 2010 Sep 17.

Published in final edited form as: Sci Signal. 2010 Aug 3; 3(133): ra59. Published online 2010 Aug 3. doi: 10.1126/scisignal.2000976

PMCID:: PMC2941205

Abstract Article PDF–1.4M

Select item 28443268.

Characterization of hydrogen peroxide production by Duox in bronchial epithelial cells exposed to Pseudomonas aeruginosa

Balázs Rada, Thomas L. Leto

FEBS Lett. Author manuscript; available in PMC 2011 Mar 5.

Published in final edited form as: FEBS Lett. 2010 Mar 5; 584(5): 917–922. Published online 2010 Jan 19. doi: 10.1016/j.febslet.2010.01.025

PMCID:: PMC2844326

Abstract Article PDF–668K

Select item 99429059.

Diet-induced obesity worsens allergen-induced type 2/type 17 inflammation in airways by enhancing DUOX1 activation

Aida Habibovic, Milena Hristova, Carolyn R. Morris, Miao-Chong Joy Lin, Litiele C. Cruz, Jennifer L. Ather, Miklós Geiszt, Vikas Anathy, Yvonne M. W. Janssen-Heininger, Matthew E. Poynter, Anne E. Dixon, Albert van der Vliet

Am J Physiol Lung Cell Mol Physiol. 2023 Feb 1; 324(2): L228–L242. Published online 2023 Jan 10. doi: 10.1152/ajplung.00331.2022

PMCID:: PMC9942905

Abstract Article

Select item 793484210.

Downregulation of epithelial DUOX1 in chronic obstructive pulmonary disease

Caspar Schiffers, Cheryl van de Wetering, Robert A. Bauer, Aida Habibovic, Milena Hristova, Christopher M. Dustin, Sara Lambrichts, Pamela M. Vacek, Emiel F.M. Wouters, Niki L. Reynaert, Albert van der Vliet

JCI Insight. 2021 Jan 25; 6(2): e142189. Published online 2021 Jan 25. doi: 10.1172/jci.insight.142189

PMCID:: PMC7934842

Abstract Article PDF–2.9M

Select item 779434311.

Structures of human dual oxidase 1 complex in low-calcium and high-calcium states

Jing-Xiang Wu, Rui Liu, Kangcheng Song, Lei Chen

Nat Commun. 2021; 12: 155. Published online 2021 Jan 8. doi: 10.1038/s41467-020-20466-9

PMCID:: PMC7794343

Abstract Article PDF–2.7M

Select item 684248512.

Dual oxidase 1 and NADPH oxidase 2 exert favorable effects in cervical cancer patients by activating immune response

Sang Yeon Cho, Sungha Kim, Mi-Ju Son, Gwanghun Kim, Parul Singh, Ha Neul Kim, Hei-Gwon Choi, Heon Jong Yoo, Young Bok Ko, Byung Seok Lee, Hyuk Soo Eun

BMC Cancer. 2019; 19: 1078. Published online 2019 Nov 9. doi: 10.1186/s12885-019-6202-3

PMCID:: PMC6842485

Abstract Article PDF–4.1M

Select item 638976513.

Congenital Hypothyroidism due to Oligogenic Mutations in Two Sudanese Families

Yui Watanabe, Ryan J. Bruellman, Reham S. Ebrhim, Mohamed A. Abdullah, Alexandra M. Dumitrescu, Samuel Refetoff, Roy E. Weiss

Thyroid. 2019 Feb 1; 29(2): 302–304. Published online 2019 Feb 11. doi: 10.1089/thy.2018.0295

PMCID:: PMC6389765

Abstract Article PDF–176K

Select item 558707914.

Digenic DUOX1 and DUOX2 Mutations in Cases With Congenital Hypothyroidism

Zehra Aycan, Hakan Cangul, Marina Muzza, Veysel N. Bas, Laura Fugazzola, V. Krishna Chatterjee, Luca Persani, Nadia Schoenmakers

J Clin Endocrinol Metab. 2017 Sep 1; 102(9): 3085–3090. Published online 2017 Jun 16. doi: 10.1210/jc.2017-00529

PMCID:: PMC5587079

Abstract Article

Select item 435828315.

The Extracellular A-loop of Dual Oxidases Affects the Specificity of Reactive Oxygen Species Release

Takehiko Ueyama, Megumi Sakuma, Yuzuru Ninoyu, Takeshi Hamada, Corinne Dupuy, Miklós Geiszt, Thomas L. Leto, Naoaki Saito

J Biol Chem. 2015 Mar 6; 290(10): 6495–6506. Published online 2015 Jan 13. doi: 10.1074/jbc.M114.592717

PMCID:: PMC4358283

Abstract Article PDF–2.6M

Select item 420024416.

Testosterone Stimulates Duox1 Activity through GPRC6A in Skin Keratinocytes

Eunbi Ko, Hyun Choi, Borim Kim, Minsun Kim, Kkot-Nara Park, Il-Hong Bae, Young Kwan Sung, Tae Ryong Lee, Dong Wook Shin, Yun Soo Bae

J Biol Chem. 2014 Oct 17; 289(42): 28835–28845. Published online 2014 Aug 27. doi: 10.1074/jbc.M114.583450

PMCID:: PMC4200244

Abstract Article PDF–1.4M

Select item 402803317.

Expression of dual oxidases and secreted cytokines in chronic rhinosinusitis

Do-Yeon Cho, Jayakar V. Nayak, Dawn T. Bravo, Wei Le, Alan Nguyen, Justin A. Edward, Peter H. Hwang, Beate Illek, Horst Fischer

Int Forum Allergy Rhinol. Author manuscript; available in PMC 2014 May 20.

Published in final edited form as: Int Forum Allergy Rhinol. 2013 May; 3(5): 376–383. Published online 2012 Dec 21. doi: 10.1002/alr.21133

PMCID:: PMC4028033

Abstract Article PDF–1.6M

Select item 394909118.

Identification of DUOX1-dependent redox signaling through protein S-glutathionylation in airway epithelial cells

Milena Hristova, Carmen Veith, Aida Habibovic, Ying-Wai Lam, Bin Deng, Miklos Geiszt, Yvonne M.W. Janssen-Heininger, Albert van der Vliet

Redox Biol. 2014; 2: 436–446. Published online 2014 Jan 15. doi: 10.1016/j.redox.2013.12.030

PMCID:: PMC3949091

Abstract Article PDF–1.4M

Select item 359162419.

Conserved Cysteine Residues Provide a Protein-Protein Interaction Surface in Dual Oxidase (DUOX) Proteins

Jennifer L. Meitzler, Sara Hinde, Botond Bánfi, William M. Nauseef, Paul R. Ortiz de Montellano

J Biol Chem. 2013 Mar 8; 288(10): 7147–7157. Published online 2013 Jan 29. doi: 10.1074/jbc.M112.414797

PMCID:: PMC3591624

Abstract Article PDF–2.4M

Select item 332769420.

Reactive Oxygen Species Regulate the Levels of Dual Oxidase (Duox1-2) in Human Neuroblastoma Cells

Simona Damiano, Roberta Fusco, Annalisa Morano, Mariarosaria De Mizio, Roberto Paternò, Antonella De Rosa, Rosa Spinelli, Stefano Amente, Rodolfo Frunzio, Paolo Mondola, Francoise Miot, Paolo Laccetti, Mariarosaria Santillo, Enrico Vittorio Avvedimento

PLoS One. 2012; 7(4): e34405. Published online 2012 Apr 16. doi: 10.1371/journal.pone.0034405