PMC Links for Gene (Select 54541) - PMC

Ekaterina M. Zhidkova, Evgeniya S. Lylova, Diana D. Grigoreva, Kirill I. Kirsanov, Alena V. Osipova, Evgeny P. Kulikov, Sergey A. Mertsalov, Gennady A. Belitsky, Irina Budunova, Marianna G. Yakubovskaya, Ekaterina A. Lesovaya

Int J Mol Sci. 2022 Sep; 23(17): 9686. Published online 2022 Aug 26. doi: 10.3390/ijms23179686

PMCID:: PMC9456073

Abstract Article PDF–5.3M

Select item 84562714.

DDIT4 S‐Nitrosylation Aids p38‐MAPK Signaling Complex Assembly to Promote Hepatic Reactive Oxygen Species Production

Zilong Li, Qianwen Zhao, Yunjie Lu, Yangxi Zhang, Luyang Li, Min Li, Xuemin Chen, Donglin Sun, Yunfei Duan, Yong Xu

Adv Sci (Weinh) 2021 Sep; 8(18): 2101957. Published online 2021 Jul 26. doi: 10.1002/advs.202101957

Correction in:: Adv Sci (Weinh). 2022 May; 9(13): 2201652.

PMCID:: PMC8456271

Abstract Article PDF–7.4M

Select item 82494075.

High expression of DNA damage-inducible transcript 4 (DDIT4) is associated with advanced pathological features in the patients with colorectal cancer

Fahimeh Fattahi, Leili Saeednejad Zanjani, Zohreh Habibi Shams, Jafar Kiani, Mitra Mehrazma, Mohammad Najafi, Zahra Madjd

Sci Rep. 2021; 11: 13626. Published online 2021 Jul 1. doi: 10.1038/s41598-021-92720-z

PMCID:: PMC8249407

Abstract Article PDF–4.0M

Select item 79562446.

The stress response protein REDD1 as a causal factor for oxidative stress in diabetic retinopathy

William P. Miller, Siddharth Sunilkumar, Michael D. Dennis

Free Radic Biol Med. Author manuscript; available in PMC 2022 Mar 1.

Published in final edited form as: Free Radic Biol Med. 2021 Mar; 165: 127–136. Published online 2021 Jan 29. doi: 10.1016/j.freeradbiomed.2021.01.041

PMCID:: PMC7956244

Abstract Article PDF–947K

Select item 69333617.

Up‐regulation of DDIT4 predicts poor prognosis in acute myeloid leukaemia

Zhiheng Cheng, Yifeng Dai, Yifan Pang, Yang Jiao, Yan Liu, Longzhen Cui, Liang Quan, Tingting Qian, Tiansheng Zeng, Chaozeng Si, Wenhui Huang, Jinghong Chen, Ying Pang, Xu Ye, Jinlong Shi, Lin Fu

J Cell Mol Med. 2020 Jan; 24(1): 1067–1075. Published online 2019 Nov 21. doi: 10.1111/jcmm.14831

PMCID:: PMC6933361

Abstract Article PDF–936K

Select item 64618558.

The physiological mTOR complex 1 inhibitor DDIT4 mediates therapy resistance in glioblastoma

Martha Foltyn, Anna-Luisa Luger, Nadja I. Lorenz, Benedikt Sauer, Michel Mittelbronn, Patrick N. Harter, Joachim P. Steinbach, Michael W. Ronellenfitsch

Br J Cancer. 2019 Mar 5; 120(5): 481–487. Published online 2019 Feb 12. doi: 10.1038/s41416-018-0368-3

PMCID:: PMC6461855

Abstract Article PDF–1.0M

Select item 62368979.

Overexpression of the recently identified oncogene REDD1 correlates with tumor progression and is an independent unfavorable prognostic factor for ovarian carcinoma

Bin Chang, Jiao Meng, Huimin Zhu, Xiang Du, Lili Sun, Lei Wang, Shugang Li, Gong Yang

Diagn Pathol. 2018; 13: 87. Published online 2018 Nov 14. doi: 10.1186/s13000-018-0754-4

PMCID:: PMC6236897

Abstract Article PDF–4.4M

Select item 543147510.

In silico evaluation of DNA Damage Inducible Transcript 4 gene (DDIT4) as prognostic biomarker in several malignancies

Joseph A. Pinto, Christian Rolfo, Luis E. Raez, Alexandra Prado, Jhajaira M. Araujo, Leny Bravo, Williams Fajardo, Zaida D. Morante, Alfredo Aguilar, Silvia P. Neciosup, Luis A. Mas, Denisse Bretel, Justin M. Balko, Henry L. Gomez

Sci Rep. 2017; 7: 1526. Published online 2017 May 8. doi: 10.1038/s41598-017-01207-3

PMCID:: PMC5431475

Abstract Article PDF–2.8M

Select item 480438911.

Iron depletion suppresses mTORC1-directed signalling in intestinal Caco-2 cells via induction of REDD1

Ailsa Watson, Christopher Lipina, Harry J. McArdle, Peter M. Taylor, Harinder S. Hundal

Cell Signal. 2016 May; 28(5): 412–424. doi: 10.1016/j.cellsig.2016.01.014

PMCID:: PMC4804389

Abstract Article

Select item 466694412.

Aberrant REDD1-mTORC1 responses to insulin in skeletal muscle from Type 2 diabetics

David L. Williamson, Cory M. Dungan, Abeer M. Mahmoud, Jacob T. Mey, Brian K. Blackburn, Jacob M. Haus

Am J Physiol Regul Integr Comp Physiol. 2015 Oct 15; 309(8): R855–R863. Published online 2015 Aug 12. doi: 10.1152/ajpregu.00285.2015

PMCID:: PMC4666944

Abstract Article

Select item 420320913.

REDD1 and p-AKT over-expression may predict poor prognosis in ovarian cancer

Wei Jia, Bin Chang, Lili Sun, Huimin Zhu, Lijuan Pang, Lin Tao, Hong Zou, Jinze Du, Yuling Dong, Yan Qi, Jinfang Jiang, Weihua Liang, Feng Li, Xia Zhao

Int J Clin Exp Pathol. 2014; 7(9): 5940–5949. Published online 2014 Aug 15.

PMCID:: PMC4203209

Abstract Article PDF–1.1M

Select item 366166414.

mTORC1 Dependent Regulation of REDD1 Protein Stability

Chia Yee Tan, Thilo Hagen

PLoS One. 2013; 8(5): e63970. Published online 2013 May 22. doi: 10.1371/journal.pone.0063970

PMCID:: PMC3661664

Abstract Article PDF–3.8M

Select item 963008315.

REDD1 Ablation Attenuates the Development of Renal Complications in Diabetic Mice

Siddharth Sunilkumar, Esma I. Yerlikaya, Allyson L. Toro, William P. Miller, Han Chen, Kebin Hu, Scot R. Kimball, Michael D. Dennis

Diabetes. 2022 Nov; 71(11): 2412–2425. Published online 2022 Aug 19. doi: 10.2337/db22-0402

PMCID:: PMC9630083

Abstract Article PDF–14M

Select item 820634416.

RTP801/REDD1 contributes to neuroinflammation severity and memory impairments in Alzheimer’s disease

Leticia Pérez-Sisqués, Anna Sancho-Balsells, Júlia Solana-Balaguer, Genís Campoy-Campos, Marcel Vives-Isern, Ferran Soler-Palazón, Marta Anglada-Huguet, Miguel-Ángel López-Toledano, Eva-Maria Mandelkow, Jordi Alberch, Albert Giralt, Cristina Malagelada

Cell Death Dis. 2021 Jun; 12(6): 616. Published online 2021 Jun 15. doi: 10.1038/s41419-021-03899-y

PMCID:: PMC8206344

Abstract Article PDF–4.8M

Select item 760979217.

A Key Role of DNA Damage-Inducible Transcript 4 (DDIT4) Connects Autophagy and GLUT3-Mediated Stemness To Desensitize Temozolomide Efficacy in Glioblastomas

Kuo-Hao Ho, Peng-Hsu Chen, Chih-Ming Chou, Chwen-Ming Shih, Yi-Ting Lee, Chia-Hsiung Cheng, Ku-Chung Chen

Neurotherapeutics. 2020 Jul; 17(3): 1212–1227. Published online 2020 Jan 8. doi: 10.1007/s13311-019-00826-0

PMCID:: PMC7609792

Abstract Article PDF–6.2M

Select item 603431318.

DDIT4 promotes gastric cancer proliferation and tumorigenesis through the p53 and MAPK pathways

Feng Du, Lina Sun, Yi Chu, Tingyu Li, Chao Lei, Xin Wang, Mingzuo Jiang, Yali Min, Yuanyuan Lu, Xiaodi Zhao, Yongzhan Nie, Daiming Fan

Cancer Commun (Lond) 2018; 38: 45. Published online 2018 Jul 5. doi: 10.1186/s40880-018-0315-y

PMCID:: PMC6034313

Abstract Article PDF–8.0M

Select item 548935719.

REDD1 deficiency impairs autophagy and mitochondrial biogenesis in articular cartilage and increases the severity of experimental osteoarthritis

Oscar Alvarez-Garcia, Tokio Matsuzaki, Merissa Olmer, Lars Plate, Jeffery W. Kelly, Martin K. Lotz

Arthritis Rheumatol. Author manuscript; available in PMC 2018 Jul 1.

Published in final edited form as: Arthritis Rheumatol. 2017 Jul; 69(7): 1418–1428. Published online 2017 Jun 2. doi: 10.1002/art.40104

PMCID:: PMC5489357

Abstract Article PDF–1.2M

Select item 531227820.

Loss of NEDD4 contributes to RTP801 elevation and neuron toxicity: implications for Parkinson's disease

Mercè Canal, Núria Martín-Flores, Leticia Pérez-Sisqués, Joan Romaní-Aumedes, Bekir Altas, Heng-Ye Man, Hiroshi Kawabe, Jordi Alberch, Cristina Malagelada

Oncotarget. 2016 Sep 13; 7(37): 58813–58831. Published online 2016 Aug 2. doi: 10.18632/oncotarget.11020