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Select item 81849881.

Targeting of VPS18 by the lysosomotropic agent RDN reverses TFE3-mediated drug resistance

Huanmin Niu, Lilin Qian, Yanhai Luo, Fang Wang, Hongbo Zheng, Yanhui Gao, Hanbo Wang, Xuelei Hu, Huiqing Yuan, Hongxiang Lou

Signal Transduct Target Ther. 2021; 6: 224. Published online 2021 Jun 7. doi: 10.1038/s41392-021-00547-x

PMCID:: PMC8184988

Article PDF–1.3M

Select item 64789102.

Vps11 and Vps18 of Vps-C membrane traffic complexes are E3 ubiquitin ligases and fine-tune signalling

Gregory Segala, Marcela A. Bennesch, Nastaran Mohammadi Ghahhari, Deo Prakash Pandey, Pablo C. Echeverria, François Karch, Robert K. Maeda, Didier Picard

Nat Commun. 2019; 10: 1833. Published online 2019 Apr 23. doi: 10.1038/s41467-019-09800-y

PMCID:: PMC6478910

Abstract Article PDF–3.4M

Select item 30949523.

The Cellular Factors Vps18 and Mon2 Are Required for Efficient Production of Infectious HIV-1 Particles

Yuriko Tomita, Takeshi Noda, Ken Fujii, Tokiko Watanabe, Yuko Morikawa, Yoshihiro Kawaoka

J Virol. 2011 Jun; 85(11): 5618–5627. doi: 10.1128/JVI.00846-10

PMCID:: PMC3094952

Abstract Article PDF–2.3M

Select item 38421784.

Vps33b pathogenic mutations preferentially affect VIPAS39/SPE-39-positive endosomes

Karine Tornieri, Stephanie A. Zlatic, Ariana P. Mullin, Erica Werner, Robert Harrison, Steven W. L'Hernault, Victor Faundez

Hum Mol Genet. 2013 Dec 20; 22(25): 5215–5228. Published online 2013 Aug 4. doi: 10.1093/hmg/ddt378

PMCID:: PMC3842178

Abstract Article PDF–1.9M

Select item 35842825.

Lysosomal Trafficking, Antigen Presentation, and Microbial Killing Are Controlled by the Arf-like GTPase Arl8b

Salil Garg, Mahak Sharma, Cindy Ung, Amit Tuli, Duarte C. Barral, David L. Hava, Natacha Veerapen, Gurdyal S. Besra, Nir Hacohen, Michael B. Brenner

Immunity. 2011 Aug 26; 35(2): 182–193. doi: 10.1016/j.immuni.2011.06.009

PMCID:: PMC3584282

Abstract Article

Select item 56518186.

VPS18 recruits VPS41 to the human HOPS complex via a RING–RING interaction

Morag R. Hunter, Edward J. Scourfield, Edward Emmott, Stephen C. Graham

Biochem J. 2017 Nov 1; 474(21): 3615–3626. Prepublished online 2017 Sep 20. Published online 2017 Oct 23. doi: 10.1042/BCJ20170588

PMCID:: PMC5651818

Abstract Article PDF–6.5M

Select item 42509147.

RILP interacts with HOPS complex via VPS41 subunit to regulate endocytic trafficking

Xiaosi Lin, Ting Yang, Shicong Wang, Zhen Wang, Ye Yun, Lixiang Sun, Yunhe Zhou, Xiaohui Xu, Chihiro Akazawa, Wanjin Hong, Tuanlao Wang

Sci Rep. 2014; 4: 7282. Published online 2014 Dec 2. doi: 10.1038/srep07282

Correction in:: Sci Rep. 2015; 5: 8302.

PMCID:: PMC4250914

Abstract Article PDF–1.8M

Select item 33849568.

HIV Assembly and Budding: Ca²⁺ Signaling and Non-ESCRT Proteins Set the Stage

Lorna S. Ehrlich, Carol A. Carter

Mol Biol Int. 2012; 2012: 851670. Published online 2012 Jun 12. doi: 10.1155/2012/851670

PMCID:: PMC3384956

Abstract Article PDF–783K

Select item 46832549.

Characterization of the Mammalian CORVET and HOPS Complexes and Their Modular Restructuring for Endosome Specificity

Rik van der Kant, Caspar T. H. Jonker, Ruud H. Wijdeven, Jeroen Bakker, Lennert Janssen, Judith Klumperman, Jacques Neefjes

J Biol Chem. 2015 Dec 18; 290(51): 30280–30290. Published online 2015 Oct 13. doi: 10.1074/jbc.M115.688440

PMCID:: PMC4683254

Abstract Article PDF–3.1M

Select item 398299710.

The HOPS complex mediates autophagosome–lysosome fusion through interaction with syntaxin 17

Peidu Jiang, Taki Nishimura, Yuriko Sakamaki, Eisuke Itakura, Tomohisa Hatta, Tohru Natsume, Noboru Mizushima

Mol Biol Cell. 2014 Apr 15; 25(8): 1327–1337. doi: 10.1091/mbc.E13-08-0447

PMCID:: PMC3982997

Abstract Article PDF–8.1M

Select item 287871611.

Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking

Chengyu Liang, Jong-soo Lee, Kyung-Soo Inn, Michaela U. Gack, Qinglin Li, Esteban A. Roberts, Isabelle Vergne, Vojo Deretic, Pinghui Feng, Chihiro Akazawa, Jae U. Jung

Nat Cell Biol. Author manuscript; available in PMC 2010 May 31.

Published in final edited form as: Nat Cell Biol. 2008 Jul; 10(7): 776–787. Published online 2008 Jun 15. doi: 10.1038/ncb1740

PMCID:: PMC2878716

Abstract Article PDF–3.2M

Select item 537994312.

The Rab7 effector PLEKHM1 binds Arl8b to promote cargo traffic to lysosomes

Rituraj Marwaha, Subhash B. Arya, Divya Jagga, Harmeet Kaur, Amit Tuli, Mahak Sharma

J Cell Biol. 2017 Apr 3; 216(4): 1051–1070. doi: 10.1083/jcb.201607085

PMCID:: PMC5379943

Abstract Article PDF–4.4M

Select item 374693713.

Structural basis of Vps33A recruitment to the human HOPS complex by Vps16

Stephen C. Graham, Lena Wartosch, Sally R. Gray, Edward J. Scourfield, Janet E. Deane, J. Paul Luzio, David J. Owen

Proc Natl Acad Sci U S A. 2013 Aug 13; 110(33): 13345–13350. Published online 2013 Jul 30. doi: 10.1073/pnas.1307074110

PMCID:: PMC3746937

Abstract Article PDF–1.1M

Select item 451070614.

Recruitment of VPS33A to HOPS by VPS16 Is Required for Lysosome Fusion with Endosomes and Autophagosomes

Lena Wartosch, Ufuk Günesdogan, Stephen C. Graham, J. Paul Luzio

Traffic. 2015 Jul; 16(7): 727–742. Published online 2015 Apr 30. doi: 10.1111/tra.12283

PMCID:: PMC4510706

Abstract Article PDF–6.4M

Select item 259267315.

An FTS/Hook/p107^FHIP Complex Interacts with and Promotes Endosomal Clustering by the Homotypic Vacuolar Protein Sorting Complex

Lai Xu, Mathew E. Sowa, Jing Chen, Xue Li, Steven P. Gygi, J. Wade Harper

Mol Biol Cell. 2008 Dec; 19(12): 5059–5071. doi: 10.1091/mbc.E08-05-0473

PMCID:: PMC2592673

Abstract Article PDF–713K

Select item 783223516.

ORF3a of the COVID-19 virus SARS-CoV-2 blocks HOPS complex-mediated assembly of the SNARE complex required for autolysosome formation

Guangyan Miao, Hongyu Zhao, Yan Li, Mingming Ji, Yong Chen, Yi Shi, Yuhai Bi, Peihui Wang, Hong Zhang

Dev Cell. 2021 Feb 22; 56(4): 427–442.e5. Published online 2020 Dec 16. doi: 10.1016/j.devcel.2020.12.010

PMCID:: PMC7832235

Abstract Article PDF–5.9M

Select item 264273917.

SPE-39 Family Proteins Interact with the HOPS Complex and Function in Lysosomal Delivery

Guang-dan Zhu, Gloria Salazar, Stephanie A. Zlatic, Babar Fiza, Michele M. Doucette, Craig J. Heilman, Allan I. Levey, Victor Faundez, Steven W. L'Hernault

Mol Biol Cell. 2009 Feb 15; 20(4): 1223–1240. doi: 10.1091/mbc.E08-07-0728

PMCID:: PMC2642739

Abstract Article PDF–1.4M

Select item 589620218.

Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability

Dominika Kwasna, Syed Arif Abdul Rehman, Jayaprakash Natarajan, Stephen Matthews, Ross Madden, Virginia De Cesare, Simone Weidlich, Satpal Virdee, Ivan Ahel, Ian Gibbs-Seymour, Yogesh Kulathu

Mol Cell. 2018 Apr 5; 70(1): 150–164.e6. doi: 10.1016/j.molcel.2018.02.023

PMCID:: PMC5896202

Abstract Article

Select item 727904919.

EDEM1 Drives Misfolded Protein Degradation via ERAD and Exploits ER-Phagy as Back-Up Mechanism When ERAD Is Impaired

Marioara Chiritoiu, Gabriela N. Chiritoiu, Cristian V. A. Munteanu, Florin Pastrama, N. Erwin Ivessa, Stefana M. Petrescu

Int J Mol Sci. 2020 May; 21(10): 3468. Published online 2020 May 14. doi: 10.3390/ijms21103468

PMCID:: PMC7279049

Abstract Article PDF–12M

Select item 334973420.

Genome-Wide Association for Abdominal Subcutaneous and Visceral Adipose Reveals a Novel Locus for Visceral Fat in Women

Caroline S. Fox, Yongmei Liu, Charles C. White, Mary Feitosa, Albert V. Smith, Nancy Heard-Costa, Kurt Lohman, GIANT Consortium, MAGIC Consortium, GLGC Consortium, Andrew D. Johnson, Meredith C. Foster, Danielle M. Greenawalt, Paula Griffin, Jinghong Ding, Anne B. Newman, Fran Tylavsky, Iva Miljkovic, Stephen B. Kritchevsky, Lenore Launer, Melissa Garcia, Gudny Eiriksdottir, J. Jeffrey Carr, Vilmunder Gudnason, Tamara B. Harris, L. Adrienne Cupples, Ingrid B. Borecki

PLoS Genet. 2012 May; 8(5): e1002695. Published online 2012 May 10. doi: 10.1371/journal.pgen.1002695

PMCID:: PMC3349734

Abstract Article PDF–377K

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