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Items: 1 to 20 of 399

1.
Ku80 gene knockdown by the CRISPR/Cas9 technique affects the biological functions of human thyroid carcinoma cells
Yali Fan, Jianying Li, Wei Wei, Hangrong Fang, Ying Duan, Namiao Li, Yingying Zhang, Jun Yu, Juanhong Wang
Oncol Rep. 2019 Dec; 42(6): 2486–2498. Published online 2019 Oct 1. doi: 10.3892/or.2019.7348
PMCID:
PMC6826323
AbstractArticlePDF–1.5M
2.
Lack of Ku80 Alteration in Multiple Myeloma
Miyuki Kato, Shinsuke Iida, Hirokazu Komatsu, Ryuzo Ueda
Jpn J Cancer Res. 2002 Apr; 93(4): 359–362. doi: 10.1111/j.1349-7006.2002.tb01264.x
PMCID:
PMC5927006
SummaryPDF–386K
3.
Clinical values of Ku80 upregulation in superficial esophageal squamous cell carcinoma
Shuai Wang, Junjie Xi, Zongwu Lin, Jiatao Hao, Can Yao, Cheng Zhan, Wei Jiang, Yu Shi, Qun Wang
Cancer Med. 2018 Apr; 7(4): 1006–1018. Published online 2018 Mar 13. doi: 10.1002/cam4.1314
PMCID:
PMC5911598
AbstractArticlePDF–819K
4.
DNA requirements for interaction of the C-terminal region of Ku80 with the DNA-dependent protein kinase catalytic subunit (DNA-PKcs)
Sarvan Kumar Radhakrishnan, Susan P. Lees-Miller
DNA Repair (Amst) Author manuscript; available in PMC 2018 Sep 1.
Published in final edited form as: DNA Repair (Amst). 2017 Sep; 57: 17–28. Published online 2017 Jun 9. doi: 10.1016/j.dnarep.2017.06.001
PMCID:
PMC5568904
AbstractArticlePDF–696K
5.
Ku80 correlates with neoadjuvant chemotherapy resistance in human lung adenocarcinoma, but reduces cisplatin/pemetrexed-induced apoptosis in A549 cells
Bin Shang, Yang Jia, Gang Chen, Zhou Wang
Respir Res. 2017; 18: 56. Published online 2017 Apr 11. doi: 10.1186/s12931-017-0545-6
PMCID:
PMC5387337
AbstractArticlePDF–2.7M
6.
The relationship between polymorphisms of XRCC5 genes with astrocytoma prognosis in the Han Chinese population
Xue He, Xikai Zhu, Lei Li, Jiayi Zhang, Ruipeng Wu, Yuan Zhang, Longli Kang, Dongya Yuan, Tianbo Jin
Oncotarget. 2016 Dec 20; 7(51): 85283–85290. Published online 2016 Nov 11. doi: 10.18632/oncotarget.13297
PMCID:
PMC5356736
AbstractArticlePDF–1.5M
7.
Impact of the Ku Complex on HIV-1 Expression and Latency
Gwenola Manic, Aurélie Maurin-Marlin, Fanny Laurent, Ilio Vitale, Sylvain Thierry, Olivier Delelis, Philippe Dessen, Michelle Vincendeau, Christine Leib-Mösch, Uriel Hazan, Jean-François Mouscadet, Stéphanie Bury-Moné
PLoS One. 2013; 8(7): e69691. Published online 2013 Jul 29. doi: 10.1371/journal.pone.0069691
PMCID:
PMC3726783
AbstractArticlePDF–1.2M
8.
Ku80 is highly expressed in lung adenocarcinoma and promotes cisplatin resistance
Qingshan Ma, Ping Li, Minyu Xu, Jinzhi Yin, Zhenzhong Su, Wei Li, Jie Zhang
J Exp Clin Cancer Res. 2012; 31(1): 99. Published online 2012 Nov 27. doi: 10.1186/1756-9966-31-99
PMCID:
PMC3527197
AbstractArticlePDF–1.5M
9.
Glucose deprivation increases nuclear DNA repair protein Ku and resistance to radiation induced oxidative stress in human cancer cells
Jie Li, Roashan Ayene, Kathleen M. Ward, Eswarkumar Dayanandam, Iraimoudi S. Ayene
Cell Biochem Funct. Author manuscript; available in PMC 2011 Jul 28.
Published in final edited form as: Cell Biochem Funct. 2009 Mar; 27(2): 93–101. doi: 10.1002/cbf.1541
PMCID:
PMC3145324
AbstractArticlePDF–1000K
10.
DNA Repair Biomarker Profiling of Head & Neck Cancer: Ku80 Expression Predicts Locoregional Failure and Death Following Radiotherapy
Benjamin J. Moeller, John S. Yordy, Michelle D. Williams, Uma Giri, Uma Raju, David P. Molkentine, Lauren A. Byers, John V. Heymach, Michael D. Story, J. Jack Lee, Erich M. Sturgis, Randal S. Weber, Adam S. Garden, K. Kian Ang, David L. Schwartz
Clin Cancer Res. Author manuscript; available in PMC 2012 Apr 1.
Published in final edited form as: Clin Cancer Res. 2011 Apr 1; 17(7): 2035–2043. Published online 2011 Feb 24. doi: 10.1158/1078-0432.CCR-10-2641
PMCID:
PMC3092475
AbstractArticlePDF–757K
11.
Ku80 gene G-1401T promoter polymorphism and risk of gastric cancer
Jia-Qi Li, Jie Chen, Nan-Nan Liu, Li Yang, Ying Zeng, Bin Wang, Xue-Rong Wang
World J Gastroenterol. 2011 Apr 28; 17(16): 2131–2136. Published online 2011 Apr 28. doi: 10.3748/wjg.v17.i16.2131
PMCID:
PMC3084400
AbstractArticlePDF–763K
12.
Ku80 facilitates chromatin binding of the telomere binding protein, TRF2
Lauren S Fink, Chad A Lerner, Paulina F Torres, Christian Sell
Cell Cycle. 2010 Sep 15; 9(18): 3798–3806. Published online 2010 Sep 15. doi: 10.4161/cc.9.18.13129
PMCID:
PMC3047804
AbstractArticlePDF–1.8M
13.
Ku Regulates the Non-Homologous End Joining Pathway Choice of DNA Double-Strand Break Repair in Human Somatic Cells
Farjana Fattah, Eu Han Lee, Natalie Weisensel, Yongbao Wang, Natalie Lichter, Eric A. Hendrickson
PLoS Genet. 2010 Feb; 6(2): e1000855. Published online 2010 Feb 26. doi: 10.1371/journal.pgen.1000855
PMCID:
PMC2829059
AbstractArticlePDF–2.0M
14.
Ku and DNA-dependent Protein Kinase Dynamic Conformations and Assembly Regulate DNA Binding and the Initial Non-homologous End Joining Complex
Michal Hammel, Yaping Yu, Brandi L. Mahaney, Brandon Cai, Ruiqiong Ye, Barry M. Phipps, Robert P. Rambo, Greg L. Hura, Martin Pelikan, Sairei So, Ramin M. Abolfath, David J. Chen, Susan P. Lees-Miller, John A. Tainer
J Biol Chem. 2010 Jan 8; 285(2): 1414–1423. Published online 2009 Nov 5. doi: 10.1074/jbc.M109.065615
PMCID:
PMC2801267
AbstractArticlePDF–2.0M
15.
Molecular analysis of Ku redox regulation
Sara M Bennett, Tracy M Neher, Andrea Shatilla, John J Turchi
BMC Mol Biol. 2009; 10: 86. Published online 2009 Aug 28. doi: 10.1186/1471-2199-10-86
PMCID:
PMC2741464
AbstractArticlePDF–686K
16.
Kinetic Analysis of the Ku-DNA Binding Activity Reveals a Redox-dependent Alteration in Protein Structure That Stimulates Dissociation of the Ku-DNA Complex
Brooke J. Andrews, Jason A. Lehman, John J. Turchi
J Biol Chem. Author manuscript; available in PMC 2008 Jun 19.
Published in final edited form as: J Biol Chem. 2006 May 12; 281(19): 13596–13603. Published online 2006 Mar 13. doi: 10.1074/jbc.M512787200
PMCID:
PMC2432111
AbstractArticlePDF–2.3M
17.
The autoantigen Ku is indistinguishable from NF IV, a protein forming multimeric protein-DNA complexes
J Exp Med. 1990 Oct 1; 172(4): 1049–1054. doi: 10.1084/jem.172.4.1049
PMCID:
PMC2188621
SummaryPDF–638K
18.
Ku80 Participates in the Targeting of Retroviral Transgenes to the Chromatin of CHO Cells
Christel Masson, Stéphanie Bury-Moné, Elvire Guiot, Asier Saez-Cirion, Damien Schoëvaërt-Brossault, Corinne Brachet-Ducos, Olivier Delelis, Frédéric Subra, Laurence Jeanson-Leh, Jean-François Mouscadet
J Virol. 2007 Aug; 81(15): 7924–7932. Published online 2007 May 16. doi: 10.1128/JVI.02015-06
PMCID:
PMC1951289
AbstractArticlePDF–454K
19.
KARP-1: a novel leucine zipper protein expressed from the Ku86 autoantigen locus is implicated in the control of DNA-dependent protein kinase activity.
K Myung, D M He, S E Lee, E A Hendrickson
EMBO J. 1997 Jun 2; 16(11): 3172–3184. doi: 10.1093/emboj/16.11.3172
PMCID:
PMC1169935
SummaryPDF–662K
20.
Isolation and characterization of cDNA encoding the 80-kDa subunit protein of the human autoantigen Ku (p70/p80) recognized by autoantibodies from patients with scleroderma-polymyositis overlap syndrome.
T Mimori, Y Ohosone, N Hama, A Suwa, M Akizuki, M Homma, A J Griffith, J A Hardin
Proc Natl Acad Sci U S A. 1990 Mar; 87(5): 1777–1781. doi: 10.1073/pnas.87.5.1777
PMCID:
PMC53566
SummaryPage BrowsePDF–1.2M

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