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Select item 64041941.

Sapropterin Treatment Prevents Congenital Heart Defects Induced by Pregestational Diabetes Mellitus in Mice

Anish Engineer, Tana Saiyin, Xiangru Lu, Andrew S. Kucey, Brad L. Urquhart, Thomas A. Drysdale, Kambiz Norozi, Qingping Feng

J Am Heart Assoc. 2018 Nov 6; 7(21): e009624. Published online 2018 Oct 23. doi: 10.1161/JAHA.118.009624

PMCID:: PMC6404194

Abstract Article PDF–3.8M

Select item 57854452.

Gata6 restricts Isl1 to the posterior of nascent hindlimb buds through Isl1 cis-regulatory modules

Naoyuki Tahara, Ryutaro Akiyama, Joshua W. M. Theisen, Hiroko Kawakami, Julia Wong, Daniel J. Garry, Yasuhiko Kawakami

Dev Biol. Author manuscript; available in PMC 2019 Feb 1.

Published in final edited form as: Dev Biol. 2018 Feb 1; 434(1): 74–83. Published online 2017 Dec 7. doi: 10.1016/j.ydbio.2017.11.013

PMCID:: PMC5785445

Abstract Article PDF–1.5M

Select item 57177583.

GATA5 Sequence Variants Identified in Individuals with Bicuspid Aortic Valve

Elizabeth M. Bonachea, Sheng-Wei Chang, Gloria Zender, Stephanie LaHaye, Sara Fitzgerald-Butt, Kim L. McBride, Vidu Garg

Pediatr Res. Author manuscript; available in PMC 2017 Dec 6.

Published in final edited form as: Pediatr Res. 2014 Aug; 76(2): 211–216. Published online 2014 May 5. doi: 10.1038/pr.2014.67

PMCID:: PMC5717758

Abstract Article PDF–832K

Select item 52556044.

Tbx20 controls the expression of the KCNH2 gene and of hERG channels

Ricardo Caballero, Raquel G. Utrilla, Irene Amorós, Marcos Matamoros, Marta Pérez-Hernández, David Tinaquero, Silvia Alfayate, Paloma Nieto-Marín, Guadalupe Guerrero-Serna, Qing-hua Liu, Roberto Ramos-Mondragón, Daniela Ponce-Balbuena, Todd Herron, Katherine F. Campbell, David Filgueiras-Rama, Rafael Peinado, José L. López-Sendón, José Jalife, Eva Delpón, Juan Tamargo

Proc Natl Acad Sci U S A. 2017 Jan 17; 114(3): E416–E425. Published online 2017 Jan 3. doi: 10.1073/pnas.1612383114

PMCID:: PMC5255604

Abstract Article PDF–2.4M

Select item 51137335.

Enhancer variants synergistically drive dysfunction of a gene regulatory network in Hirschsprung disease

Sumantra Chatterjee, Ashish Kapoor, Jennifer A. Akiyama, Dallas R. Auer, Dongwon Lee, Stacey Gabriel, Courtney Berrios, Len A. Pennacchio, Aravinda Chakravarti

Cell. Author manuscript; available in PMC 2017 Oct 6.

Published in final edited form as: Cell. 2016 Oct 6; 167(2): 355–368.e10. Published online 2016 Sep 29. doi: 10.1016/j.cell.2016.09.005

PMCID:: PMC5113733

Abstract Article PDF–1.4M

Select item 49826936.

HIRA Is Required for Heart Development and Directly Regulates Tnni2 and Tnnt3

Daniel Dilg, Rasha Noureldin M. Saleh, Sarah Elizabeth Lee Phelps, Yoann Rose, Laurent Dupays, Cian Murphy, Timothy Mohun, Robert H. Anderson, Peter J. Scambler, Ariane L. A. Chapgier

PLoS One. 2016; 11(8): e0161096. Published online 2016 Aug 12. doi: 10.1371/journal.pone.0161096

PMCID:: PMC4982693

Abstract Article PDF–18M

Select item 46965167.

Endothelial Gata5 transcription factor regulates blood pressure

Smail Messaoudi, Ying He, Alex Gutsol, Andrew Wight, Richard L. Hébert, Ragnar O. Vilmundarson, Andrew P. Makrigiannis, John Chalmers, Pavel Hamet, Johanne Tremblay, Ruth McPherson, Alexandre F. R. Stewart, Rhian M. Touyz, Mona Nemer

Nat Commun. 2015; 6: 8835. Published online 2015 Nov 30. doi: 10.1038/ncomms9835

PMCID:: PMC4696516

Abstract Article PDF–2.2M

Select item 44482818.

Principal component analysis-based unsupervised feature extraction applied to in silico drug discovery for posttraumatic stress disorder-mediated heart disease

Y-h Taguchi, Mitsuo Iwadate, Hideaki Umeyama

BMC Bioinformatics. 2015; 16: 139. Published online 2015 Apr 30. doi: 10.1186/s12859-015-0574-4

PMCID:: PMC4448281

Abstract Article PDF–4.3M

Select item 40477169.

Induction of WNT inhibitory factor 1 expression by Müllerian inhibiting substance/AntiMullerian hormone in the Müllerian duct mesenchyme is linked to Müllerian duct regression

Joo Hyun Park, Yoshihiro Tanaka, Nelson A. Arango, Lihua Zhang, L. Andrew Benedict, Mi In Roh, Patricia K. Donahoe, Jose M. Teixeira

Dev Biol. Author manuscript; available in PMC 2015 Feb 1.

Published in final edited form as: Dev Biol. 2014 Feb 1; 386(1): 227–236. Published online 2013 Dec 19. doi: 10.1016/j.ydbio.2013.12.015

PMCID:: PMC4047716

Abstract Article PDF–814K

Select item 394214310.

N-Acetylcysteine prevents congenital heart defects induced by pregestational diabetes

Hoda Moazzen, Xiangru Lu, Noelle L Ma, Thomas J Velenosi, Brad L Urquhart, Lambertus J Wisse, Adriana C Gittenberger-de Groot, Qingping Feng

Cardiovasc Diabetol. 2014; 13: 46. Published online 2014 Feb 18. doi: 10.1186/1475-2840-13-46

PMCID:: PMC3942143

Abstract Article PDF–1.7M

Select item 380887011.

Candidate genes for limiting cholestatic intestinal injury identified by gene expression profiling

Samuel M Alaish, Jennifer Timmons, Alexis Smith, Marguerite S Buzza, Ebony Murphy, Aiping Zhao, Yezhou Sun, Douglas J Turner, Terez Shea-Donahue, Toni M Antalis, Alan Cross, Susan G Dorsey

Physiol Rep. 2013 Sep; 1(4): e00073. Published online 2013 Sep 17. doi: 10.1002/phy2.73

PMCID:: PMC3808870

Abstract Article PDF–1.2M

Select item 339796112.

Twist1 Transcriptional Targets in the Developing Atrio-Ventricular Canal of the Mouse

Pavle Vrljicak, Rebecca Cullum, Eric Xu, Alex C. Y. Chang, Elizabeth D. Wederell, Mikhail Bilenky, Steven J. M. Jones, Marco A. Marra, Aly Karsan, Pamela A. Hoodless

PLoS One. 2012; 7(7): e40815. Published online 2012 Jul 16. doi: 10.1371/journal.pone.0040815

PMCID:: PMC3397961

Abstract Article PDF–1.0M

Select item 333491113.

Deficient Signaling via Alk2 (Acvr1) Leads to Bicuspid Aortic Valve Development

Penny S. Thomas, Somyoth Sridurongrit, Pilar Ruiz-Lozano, Vesa Kaartinen

PLoS One. 2012; 7(4): e35539. Published online 2012 Apr 19. doi: 10.1371/journal.pone.0035539

PMCID:: PMC3334911

Abstract Article PDF–3.0M

Select item 327003414.

Conditional Ablation of Ezh2 in Murine Hearts Reveals Its Essential Roles in Endocardial Cushion Formation, Cardiomyocyte Proliferation and Survival

Li Chen, Yanlin Ma, Eun Young Kim, Wei Yu, Robert J. Schwartz, Ling Qian, Jun Wang

PLoS One. 2012; 7(2): e31005. Published online 2012 Feb 1. doi: 10.1371/journal.pone.0031005

PMCID:: PMC3270034

Abstract Article PDF–2.4M

Select item 308118215.

Transcriptional Repression of Caveolin-1 (CAV1) Gene Expression by GATA-6 in Bladder Smooth Muscle Hypertrophy in Mice and Human Beings

Ettickan Boopathi, Cristiano Mendes Gomes, Robert Goldfarb, Mary John, Vittala Gopal Srinivasan, Jaber Alanzi, S. Bruce Malkowicz, Hasmeena Kathuria, Stephen A. Zderic, Alan J. Wein, Samuel Chacko

Am J Pathol. 2011 May; 178(5): 2236–2251. doi: 10.1016/j.ajpath.2011.01.038

PMCID:: PMC3081182

Abstract Article PDF–3.2M

Select item 295645616.

Alteration of Differentiation Potentials by Modulating GATA Transcription Factors in Murine Embryonic Stem Cells

Callinice D. Capo-chichi, Jennifer L. Smedberg, Malgorzata Rula, Emmanuelle Nicolas, Anthony T. Yeung, Richard F. Adamo, Andrey Frolov, Andrew K. Godwin, Xiang-Xi Xu

Stem Cells Int. 2010; 2010: 602068. Published online 2010 May 11. doi: 10.4061/2010/602068