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Items: 1 to 20 of 1175

1.
Apigenin and its combination with Vorinostat induces apoptotic-mediated cell death in TNBC by modulating the epigenetic and apoptotic regulators and related miRNAs
Snehal Nimal, Navanath Kumbhar, Saruchi, Shriya Rathore, Nitin Naik, Sneha Paymal, Rajesh N. Gacche
Sci Rep. 2024; 14: 9540. Published online 2024 Apr 25. doi: 10.1038/s41598-024-60395-x
PMCID:
PMC11045774
AbstractArticlePDF–3.9M
2.
EBV-transformed lymphoblastoid cell lines as vaccines against cancer testis antigen-positive tumors
Frank Neumann, Dominic Kaddu-Mulindwa, Thomas Widmann, Klaus-Dieter Preuss, Gerhard Held, Carsten Zwick, Klaus Roemer, Michael Pfreundschuh, Boris Kubuschok
Cancer Immunol Immunother. 2013 Jul; 62(7): 1211–1222. Published online 2013 Apr 26. doi: 10.1007/s00262-013-1412-z
PMCID:
PMC11028802
AbstractArticlePDF–405K
3.
Suberoylanilide hydroxamic acid attenuates cognitive impairment in offspring caused by maternal surgery during mid-pregnancy
Yunlin Feng, Jia Qin, Yanfei Lu, Mengdie Wang, Shengqiang Wang, Foquan Luo
PLoS One. 2024; 19(3): e0295096. Published online 2024 Mar 29. doi: 10.1371/journal.pone.0295096
PMCID:
PMC10980197
AbstractArticlePDF–2.0M
4.
Inhibition of mitochondrial translocase SLC25A5 and histone deacetylation is an effective combination therapy in neuroblastoma
Janith A. Seneviratne, Daniel R. Carter, Rituparna Mittra, Andrew Gifford, Patrick Y. Kim, Jie‐Si Luo, Chelsea Mayoh, Alice Salib, Aldwin S. Rahmanto, Jayne Murray, Ngan C. Cheng, Zsuzsanna Nagy, Qian Wang, Ane Kleynhans, Owen Tan, Selina K. Sutton, Chengyuan Xue, Sylvia A. Chung, Yizhuo Zhang, Chengtao Sun, Li Zhang, Michelle Haber, Murray D. Norris, Jamie I. Fletcher, Tao Liu, Pierre J. Dilda, Philip J. Hogg, Belamy B. Cheung, Glenn M. Marshall
Int J Cancer. 2023 Apr 1; 152(7): 1399–1413. Published online 2022 Nov 17. doi: 10.1002/ijc.34349
PMCID:
PMC10953412
AbstractArticlePDF–7.6M
5.
The addition of vorinostat to lenalidomide maintenance for patients with newly diagnosed multiple myeloma of all ages: results from ‘Myeloma XI’, a multicentre, open‐label, randomised, phase III trial
Matthew W. Jenner, Charlotte Pawlyn, Faith E. Davies, Tom Menzies, Anna Hockaday, Catherine Olivier, John R. Jones, Kamaraj Karunanithi, Jindriska Lindsay, Bhuvan Kishore, Gordon Cook, Mark T. Drayson, Martin F. Kaiser, Roger G. Owen, Walter Gregory, David A. Cairns, Gareth J. Morgan, Graham H. Jackson, for the UK National Cancer Research Institute (NCRI) Haemato‐oncology Clinical Studies Group
Br J Haematol. 2023 Apr; 201(2): 267–279. Published online 2022 Dec 21. doi: 10.1111/bjh.18600
PMCID:
PMC10952726
AbstractArticlePDF–1.6M
6.
Pan-histone deacetylase inhibitor vorinostat suppresses osteoclastic bone resorption through modulation of RANKL-evoked signaling and ameliorates ovariectomy-induced bone loss
Xiaole Peng, Tianhao Wang, Qing Wang, Yuhu Zhao, Hao Xu, Huilin Yang, Ye Gu, Yunxia Tao, Bangsheng Yan, Yaozeng Xu, Dechun Geng
Cell Commun Signal. 2024; 22: 160. Published online 2024 Mar 4. doi: 10.1186/s12964-024-01525-w
PMCID:
PMC10913587
AbstractArticlePDF–11M
7.
Chemical Epigenetic Regulation Secondary Metabolites Derived from Aspergillus sydowii DL1045 with Inhibitory Activities for Protein Tyrosine Phosphatases
Xuan Shi, Xia Li, Xiaoshi He, Danyang Zhang, Chunshan Quan, Zhilong Xiu, Yuesheng Dong
Molecules. 2024 Feb; 29(3): 670. Published online 2024 Jan 31. doi: 10.3390/molecules29030670
PMCID:
PMC10856041
AbstractArticlePDF–3.7M
8.
Results from a phase I trial of pembrolizumab plus vorinostat in relapsed/refractory B-cell non-Hodgkin lymphoma
James Godfrey, Matthew Mei, Lu Chen, Joo Y. Song, Victoria Bedell, L. Elizabeth Budde, Saro Armenian, Sandrine Puverel, Liana Nikolaenko, Robert Chen, Shari Daniels, Neena Kennedy, Lacolle Peters, Steven T. Rosen, Stephen J. Forman, Leslie L. Popplewell, Larry W. Kwak, Alex F. Herrera
Haematologica. 2024 Feb 1; 109(2): 533–542. Published online 2023 Jul 20. doi: 10.3324/haematol.2023.283002
PMCID:
PMC10828763
AbstractArticlePDF–3.1M
9.
Suberoylanilide Hydroxamic Acid Analogs with Heteroaryl Amide Group and Different Chain Length: Synthesis and Effect on Histone Deacetylase
Gabriele Micheletti, Carla Boga, Giacomo Drius, Silvia Bordoni, Natalia Calonghi
Molecules. 2024 Jan; 29(1): 238. Published online 2024 Jan 1. doi: 10.3390/molecules29010238
PMCID:
PMC10781187
AbstractArticlePDF–11M
10.
Network and Computational Drug Repurposing Analysis for c-Myc Inhibition in Burkitt Lymphoma
YONGMIN LEE, SEUNGYOON NAM
Cancer Genomics Proteomics. 2023 Nov-Dec; 20(6 Suppl): 712–722. Published online 2023 Nov 3. doi: 10.21873/cgp.20418
PMCID:
PMC10687731
AbstractArticlePDF–5.5M
11.
Regulatory Roles of Histone Deacetylation in Metabolic Stress-Induced Expression of Caspase Recruitment Domain-Containing Protein 9 (CARD9) in Pancreatic β-Cells
Mirabela Hali, Nelson Pinto, Noah Gleason, Anjaneyulu Kowluru
Int J Mol Sci. 2023 Nov; 24(21): 15994. Published online 2023 Nov 6. doi: 10.3390/ijms242115994
PMCID:
PMC10647342
AbstractArticlePDF–1.1M
12.
KLF5 Promotes Tumor Progression and Parp Inhibitor Resistance in Ovarian Cancer
Yong Wu, Siyu Chen, Yang Shao, Ying Su, Qin Li, Jiangchun Wu, Jun Zhu, Hao Wen, Yan Huang, Zhong Zheng, Xiaojun Chen, Xingzhu Ju, Shenglin Huang, Xiaohua Wu, Zhixiang Hu
Adv Sci (Weinh) 2023 Nov; 10(31): 2304638. Published online 2023 Sep 13. doi: 10.1002/advs.202304638
PMCID:
PMC10625120
AbstractArticlePDF–4.3M
13.
Suberoylanilide hydroxamic acid upregulates reticulophagy receptor expression and promotes cell death in hepatocellular carcinoma cells
Jia-Yao Li, Tian Tian, Bing Han, Ting Yang, Yi-Xin Guo, Jia-Yu Wu, Yu-Si Chen, Qin Yang, Ru-Jia Xie
World J Gastroenterol. 2023 Sep 14; 29(34): 5038–5053. Published online 2023 Sep 14. doi: 10.3748/wjg.v29.i34.5038
PMCID:
PMC10518741
AbstractArticlePDF–20M
14.
Drug repurposing based on differentially expressed genes suggests drug combinations with possible synergistic effects in treatment of lung adenocarcinoma
Liora Yesharim, Shahram Teimourian
Cancer Biol Ther. 2023; 24(1): 2253586. Published online 2023 Sep 14. doi: 10.1080/15384047.2023.2253586
PMCID:
PMC10506443
AbstractArticlePDF–5.9M
15.
Thioredoxin-interacting protein-activated intracellular potassium deprivation mediates the anti-tumour effect of a novel histone acetylation inhibitor HL23, a fangchinoline derivative, in human hepatocellular carcinoma
Yuanjun Lu, Yazhou Liu, Junjie Lan, Yau-Tuen Chan, Zixin Feng, Lan Huang, Ning Wang, Weidong Pan, Yibin Feng
J Adv Res. 2023 Sep; 51: 181–196. Published online 2022 Nov 9. doi: 10.1016/j.jare.2022.10.017
PMCID:
PMC10491973
AbstractArticlePDF–6.5M
16.
A Bifunctional PARP-HDAC Inhibitor with Activity in Ewing Sarcoma
Louise Ramos, Sarah Truong, Beibei Zhai, Jay Joshi, Fariba Ghaidi, Michael M. Lizardo, Taras Shyp, Sonia H.Y. Kung, Alireza M. Rezakhanlou, Htoo Zarni Oo, Hans Adomat, Stephane Le Bihan, Colin Collins, Jeffrey Bacha, Dennis Brown, John Langlands, Wang Shen, Nada Lallous, Poul H. Sorensen, Mads Daugaard
Clin Cancer Res. 2023 Sep 1; 29(17): 3541–3553. Published online 2023 Jun 6. doi: 10.1158/1078-0432.CCR-22-3897
PMCID:
PMC10472104
AbstractArticlePDF–15M
17.
LRP5, SLC6A3, and SOX10 Expression in Conventional Ameloblastoma
Lorena Correa-Arzate, Javier Portilla-Robertson, Josué Orlando Ramírez-Jarquín, Luis Fernando Jacinto-Alemán, Claudia Patricia Mejía-Velázquez, Francisco Germán Villanueva-Sánchez, Mariana Rodríguez-Vázquez
Genes (Basel) 2023 Aug; 14(8): 1524. Published online 2023 Jul 26. doi: 10.3390/genes14081524
PMCID:
PMC10453908
AbstractArticlePDF–2.2M
18.
Histone Deacetylase Inhibitor (SAHA) Reduces Mortality in an Endotoxemia Mouse Model by Suppressing Glycolysis
Yunchen Wu, Yudan He, Chen Liu, Charlotte Ehle, Aishwarya Iyer-Bierhoff, Bing Liu, Thorsten Heinzel, Shaojun Xing
Int J Mol Sci. 2023 Aug; 24(15): 12448. Published online 2023 Aug 4. doi: 10.3390/ijms241512448
PMCID:
PMC10418975
AbstractArticlePDF–3.5M
19.
洛伐他汀或辛伐他汀协同组蛋白去乙酰化酶抑制剂对人非小细胞肺癌的抑制作用
Gui-kai LIANG, Zhang-ting YAO, Jie-qiong ZHANG, Xi CHEN, Rui-yang LIU, Hui-hui CHEN, Hong-hai WU, Lu JIN, Ling DING
Zhejiang Da Xue Xue Bao Yi Xue Ban. 2015 Jan 25; 44(5): 500–505. Chinese. doi: 10.3785/j.issn.1008-9292.2015.09.05
PMCID:
PMC10400818
AbstractArticlePDF–783K
20.
Vorinostat-induced acetylation of RUNX3 reshapes transcriptional profile through long-range enhancer-promoter interactions in natural killer cells
Eun-Chong Lee, Kyungwoo Kim, Woong-Jae Jung, Hyoung-Pyo Kim
BMB Rep. 2023 Jul 31; 56(7): 398–403. Published online 2023 Jul 31. doi: 10.5483/BMBRep.2023-0044
PMCID:
PMC10390292
AbstractArticlePDF–7.9M

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