Abstract
Florfenicol is an antibiotic approved for veterinary use in cattle in the United States in 1996. Although this drug is not used in poultry, we have detected resistance to florfenicol in clinical isolates of avian Escherichia coli. Molecular typing demonstrated that the florfenicol resistance gene, flo, was independently acquired and is plasmid encoded.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Anti-Bacterial Agents / pharmacology*
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Chickens / microbiology
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Drug Resistance, Microbial / genetics
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Escherichia coli / drug effects
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Escherichia coli / genetics*
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Escherichia coli / isolation & purification
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Escherichia coli Infections / veterinary*
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Genes, Bacterial
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Plasmids / genetics
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Poultry Diseases / microbiology
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Thiamphenicol / analogs & derivatives*
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Thiamphenicol / pharmacology
Substances
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Anti-Bacterial Agents
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florfenicol
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Thiamphenicol