Further evidence for a link between melarsoprol resistance and P2 transporter function in African trypanosomes

Mol Biochem Parasitol. 2000 Feb 25;106(1):181-5. doi: 10.1016/s0166-6851(99)00206-6.
No abstract available

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antiprotozoal Agents / pharmacology
  • Arsenicals / pharmacology
  • Biological Transport, Active
  • Dose-Response Relationship, Drug
  • Drug Resistance / genetics
  • Melarsoprol / pharmacology*
  • Mice
  • Mice, Inbred BALB C
  • Minisatellite Repeats
  • Purines / metabolism*
  • Trypanocidal Agents / pharmacology*
  • Trypanosoma brucei brucei / drug effects*
  • Trypanosoma brucei brucei / genetics

Substances

  • Antiprotozoal Agents
  • Arsenicals
  • Purines
  • Trypanocidal Agents
  • melarsen oxide
  • Melarsoprol