Abstract
Four new cytotoxic neolignans, machilusol A (1), machilusol C (3), machilusol D (4), machilusol E (5) as well as two new inactive neolignans, machilusol B (2) and machilusol F (6), were isolated from the stem wood of Machilus obovatifolia. All structures were identified by means of spectroscopic analysis.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Antineoplastic Agents, Phytogenic / chemistry
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Antineoplastic Agents, Phytogenic / isolation & purification*
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Antineoplastic Agents, Phytogenic / pharmacology
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Benzoquinones
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Colorimetry
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HT29 Cells
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Humans
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Imines
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Indicators and Reagents
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Lignans / chemistry
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Lignans / isolation & purification*
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Lignans / pharmacology
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Magnetic Resonance Spectroscopy
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Mass Spectrometry
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Mice
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Plant Extracts / chemistry*
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Plant Stems / chemistry
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Trees / chemistry*
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Tumor Cells, Cultured
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Wood
Substances
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Antineoplastic Agents, Phytogenic
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Benzoquinones
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Imines
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Indicators and Reagents
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Lignans
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Plant Extracts
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N,2,6-trichloro-4-benzoquinone imine