A new cembranolide from the soft coral Sinularia capillosa

J Nat Prod. 2000 Nov;63(11):1543-5. doi: 10.1021/np0000264.

Abstract

A new cembranolide, capillolide (1), and three known cembranolides were isolated from the soft coral Sinularia capillosa collected from the South China Sea. Their structures and the relative stereochemistry of 1 were deduced on the basis of spectroscopic methods.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antineoplastic Agents / isolation & purification*
  • Antineoplastic Agents / pharmacology
  • Cnidaria / chemistry*
  • Diterpenes / chemistry*
  • Diterpenes / isolation & purification
  • Leukemia L1210 / drug therapy
  • Leukemia P388 / drug therapy
  • Magnetic Resonance Spectroscopy
  • Spectrometry, Mass, Fast Atom Bombardment
  • Tumor Cells, Cultured

Substances

  • Antineoplastic Agents
  • Diterpenes
  • capillolide