This study sought to evaluate the knowledge and attitudes of U.S. high school girls regarding infant feeding to determine if they might be effective targets for breastfeeding promotion strategies. A survey was administered to 100 teenagers in two suburban high schools in the United States. Seventy-nine percent of the girls expected to have children, but only 52% planned to breastfeed. Girls who were breastfed were more likely to plan to breastfeed (83% vs. 35%), as were girls with exposure to breastfeeding (62% vs. 45%). Girls exposed to breastfeeding were more likely to see breastfeeding as beneficial to both the mother (45% vs. 24%) and the infant (86% vs. 60%) and to be interested in breastfeeding education (31% vs. 17%). Teenagers may be an important target group for breastfeeding promotion because many consider the choice of infant feeding before planning pregnancy and have not yet decided whether to breastfeed.