A conserved mechanism for post-transcriptional gene silencing?

Genome Biol. 2000;1(3):REVIEWS1018. doi: 10.1186/gb-2000-1-3-reviews1018. Epub 2000 Sep 13.

Abstract

Proteins with homology to RNA-directed RNA polymerases function in post-transcriptional gene silencing: in quelling in the fungus Neurospora crassa, RNAi in the nematode Caenorhabditis elegans, and co-suppression in the mustard plant Arabidopsis thaliana. These findings are consistent with a conserved mechanism operating in these diverse species.

Publication types

  • Review

MeSH terms

  • Animals
  • Arabidopsis / enzymology
  • Arabidopsis / genetics
  • Arabidopsis Proteins*
  • Conserved Sequence / genetics
  • Evolution, Molecular*
  • Gene Silencing*
  • Genes, Plant / genetics
  • Plant Proteins / genetics
  • Plant Proteins / metabolism
  • RNA-Dependent RNA Polymerase / genetics
  • RNA-Dependent RNA Polymerase / metabolism*
  • Transcription, Genetic / genetics*

Substances

  • Arabidopsis Proteins
  • Plant Proteins
  • SGS3 protein, Arabidopsis
  • RNA-Dependent RNA Polymerase