Abstract
Four new alkaloids, nauclealines A (1) and B (2) and naucleosides A (3) and B (4), together with six known compounds, strictosamide (5), vincosamide (6), pumiloside (7), kelampayoside A, sitosterol, and sitosteryl beta-D-glucoside, were isolated from the bark of Nauclea orientalis. The structures of 1-4 were elucidated using 1D and 2D NMR spectral methods, including COSY, DEPT, HMQC, (13)C-(1)H HMBC, and (15)N-(1)H HMBC.
Publication types
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Research Support, U.S. Gov't, Non-P.H.S.
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Alkaloids / chemistry*
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Alkaloids / isolation & purification*
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Chromatography, Thin Layer
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Indoles / chemistry*
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Indoles / isolation & purification*
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Magnetic Resonance Spectroscopy
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Molecular Structure
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Papua New Guinea
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Plant Stems / chemistry
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Plants, Medicinal / chemistry*
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Rubiaceae / chemistry*
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Spectrophotometry, Infrared
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Spectrophotometry, Ultraviolet
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Spectroscopy, Fourier Transform Infrared