Calcium fortification of breakfast cereal enhances calcium absorption in children without affecting iron absorption

J Pediatr. 2001 Oct;139(4):522-6. doi: 10.1067/mpd.2001.116936.

Abstract

Objectives: Provision of calcium-fortified foods may represent an important component of improving the calcium intake of children. We sought to determine whether the addition of calcium to cereal would have a net positive effect on calcium absorption without decreasing iron absorption.

Methods: Twenty-seven children, 6 to 9 years of age, were provided two servings per day (30 g of cereal per serving) of either a low (39 mg/serving) or fortified (156 mg/serving) calcium-containing cereal product for 14 days. Calcium absorption was measured by using stable isotopes added to milk (extrinsically labeled) and to the calcium-fortified cereal (intrinsically labeled).

Results: Fractional calcium absorption from the fortified cereal was virtually identical to that from milk. Fractional absorption of calcium from milk did not differ significantly when given with enriched or low-calcium-containing cereal. Total calcium absorption increased from 215 +/- 45 mg/d to 269 +/- 45 mg/d with the addition of the calcium-fortified cereal (P <.001). Iron absorption was similar when children received the calcium-fortified cereal or unfortified cereal.

Conclusions: The addition of a moderate amount of calcium to a cereal product was beneficial to calcium absorption and did not interfere with iron absorption. Use of calcium-fortified food products may be considered a practical approach to increasing the calcium intake of children.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Absorption / physiology
  • Animals
  • Calcium, Dietary / metabolism*
  • Child
  • Child Nutritional Physiological Phenomena*
  • Diet Records
  • Edible Grain / metabolism*
  • Female
  • Fluoroimmunoassay
  • Food, Fortified*
  • Humans
  • Iron, Dietary / metabolism*
  • Isotope Labeling
  • Male
  • Milk / metabolism

Substances

  • Calcium, Dietary
  • Iron, Dietary