Transdermal delivery of antisense oligonucleotides with microprojection patch (Macroflux) technology

Pharm Res. 2001 Dec;18(12):1789-93. doi: 10.1023/a:1013395102049.
No abstract available

MeSH terms

  • Administration, Cutaneous
  • Animals
  • Dose-Response Relationship, Drug
  • Drug Delivery Systems / methods*
  • Guinea Pigs
  • Iontophoresis
  • Liver / chemistry
  • Microinjections / methods*
  • Oligonucleotides, Antisense / administration & dosage*
  • Oligonucleotides, Antisense / pharmacokinetics
  • Skin / chemistry
  • Time Factors

Substances

  • Oligonucleotides, Antisense