Abstract
Gibbilimbols A-D (1-4) were synthesized in 32-49% yield over four steps from commercially available starting materials. A copper-catalyzed coupling of 4-methoxyphenylmagnesium bromide with various unsaturated alkyl bromides was the key step in assembling the (long-chain alkyl)phenol skeleton.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Catalysis
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Chemistry, Organic / methods
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Copper / chemistry
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Gas Chromatography-Mass Spectrometry
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Molecular Structure
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Nuclear Magnetic Resonance, Biomolecular
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Phenols / chemical synthesis*
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Phenols / chemistry
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Piperaceae / chemistry*
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Plants, Medicinal / chemistry*
Substances
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Phenols
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gibbilimbol A
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gibbilimbol B
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gibbilimbol C
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gibbilimbol D
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Copper