Formation of new lipoaminopeptides, acremostatins A, B, and C, by co-cultivation of Acremonium sp. Tbp-5 and Mycogone rosea DSM 12973

Thomas Degenkolb; Stephan Heinze; Brigitte Schlegel; Gary Strobel; Udo Gräfe

doi:10.1271/bbb.66.883

Formation of new lipoaminopeptides, acremostatins A, B, and C, by co-cultivation of Acremonium sp. Tbp-5 and Mycogone rosea DSM 12973

Biosci Biotechnol Biochem. 2002 Apr;66(4):883-6. doi: 10.1271/bbb.66.883.

Authors

Thomas Degenkolb¹, Stephan Heinze, Brigitte Schlegel, Gary Strobel, Udo Gräfe

Affiliation

¹ Hans-Knöll-Institute for Natural Products Research, Jena, Germany.

PMID: 12036069
DOI: 10.1271/bbb.66.883

Abstract

Formation of new lipoaminopeptides, acremostatins A, B, and C, was observed during co-cultivation of Acremonium sp. Tbp-5 and Mycogone rosea DSM 12973. Thus, co-cultivation of microorganisms producing related products could be suggested as a suitable way towards diversification of microbial structures.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Acremonium / growth & development
Acremonium / metabolism*
Amino Acid Sequence
Hypocreales / growth & development
Hypocreales / metabolism*
Lipoproteins / biosynthesis*
Oligopeptides / biosynthesis*
Peptide Fragments / chemistry
Peptide Fragments / isolation & purification
Spectrometry, Mass, Electrospray Ionization

Substances

Lipoproteins
Oligopeptides
Peptide Fragments