A C-terminal domain of the membrane copper pump Ctr1 exchanges copper(I) with the copper chaperone Atx1

Zhiguang Xiao; Anthony G Wedd

doi:10.1039/b111180a

A C-terminal domain of the membrane copper pump Ctr1 exchanges copper(I) with the copper chaperone Atx1

Chem Commun (Camb). 2002 Mar 21:(6):588-9. doi: 10.1039/b111180a.

Authors

Zhiguang Xiao¹, Anthony G Wedd

Affiliation

¹ School of Chemistry, University of Melbourne, Parkville, Victoria 3010, Australia.

PMID: 12120136
DOI: 10.1039/b111180a

Abstract

A cloned C-terminal domain of the yeast high-affinity copper uptake pump Ctr1 exchanges Cu(I) rapidly with the yeast copper chaperone Atx1: 10(-2) < Kex < 10(+2).

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Biological Transport
Cation Transport Proteins*
Chromatography, High Pressure Liquid
Cloning, Molecular
Copper / metabolism*
Copper Transporter 1
Membrane Proteins / chemistry
Membrane Proteins / metabolism*
Models, Chemical
Protein Structure, Tertiary
Saccharomyces cerevisiae / chemistry
Saccharomyces cerevisiae / metabolism
Saccharomyces cerevisiae Proteins*

Substances

CTR1 protein, S cerevisiae
Cation Transport Proteins
Copper Transporter 1
Membrane Proteins
Saccharomyces cerevisiae Proteins
Copper