Abstract
[reaction: see text] Natural 6-epiplakortolide E was first synthesized from readily available 1-bromo-10-phenyldecane in 10 steps by using singlet oxygen-mediated Diels-Alder reaction to form cyclic peroxide followed by a directed iodolactonization to give the peroxylactone core.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Biological Factors / chemical synthesis*
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Biological Factors / chemistry
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Lactones / chemical synthesis*
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Lactones / chemistry
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Magnetic Resonance Spectroscopy
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Molecular Structure
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Peroxides / chemical synthesis*
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Peroxides / chemistry
Substances
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6-epiplakortolide E
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Biological Factors
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Lactones
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Peroxides