Triterpenoids from Rubia yunnanensis

J Nat Prod. 2002 Sep;65(9):1283-7. doi: 10.1021/np020038k.

Abstract

Five new triterpenoids, rubiarbonones D (1), E (5), and F (2), and rubiarbosides F (3) and G (4), together with nine known compounds, were isolated from the roots of Rubia yunnanensis. The structures of 1-12 were elucidated by spectroscopic methods. The antiplatelet aggregation activities of rubiarbonone A (6) and rubiarbonol A (8) and B (9) were investigated with a standard protocol.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Drugs, Chinese Herbal / chemistry*
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Plant Roots / chemistry
  • Platelet Aggregation / drug effects
  • Platelet Aggregation Inhibitors / chemistry
  • Platelet Aggregation Inhibitors / isolation & purification*
  • Platelet Aggregation Inhibitors / pharmacology
  • Rubiaceae / chemistry*
  • Triterpenes / chemistry
  • Triterpenes / isolation & purification*
  • Triterpenes / pharmacology

Substances

  • Drugs, Chinese Herbal
  • Platelet Aggregation Inhibitors
  • Triterpenes
  • rubiarbonone D
  • rubiarbonone E
  • rubiarbonone F
  • rubiarboside F
  • rubiarboside G