Abstract
NZF-2 (MyT1) is a member of C2HC-type zinc finger transcription factors. A novel form of mouse NZF-2 has been isolated. This novel form, NZF-2b, has an additional C2HC-type zinc finger motif. The expression levels of NZF-2b are by far the more predominant than those of the already known form of NZF-2. In embryonic mouse nervous system, the expression of NZF-2b starts as early as at 9.5 days post-coitum (dpc) in newly differentiated neurons in the central nervous system (CNS) and the peripheral nervous system (PNS).
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acid Motifs
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Amino Acid Sequence
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Animals
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Cell Differentiation
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Central Nervous System / embryology
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DNA, Complementary / metabolism
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DNA-Binding Proteins / biosynthesis*
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DNA-Binding Proteins / genetics*
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Immunohistochemistry
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In Situ Hybridization
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Mice
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Models, Genetic
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Molecular Sequence Data
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Nervous System / embryology
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Neurons / metabolism*
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Reverse Transcriptase Polymerase Chain Reaction
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Sequence Homology, Amino Acid
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Spinal Cord / embryology
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Time Factors
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Transcription Factors / biosynthesis*
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Transcription Factors / genetics*
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Transcription, Genetic
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Zinc Fingers*
Substances
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DNA, Complementary
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DNA-Binding Proteins
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Myt1 protein, mouse
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Transcription Factors