Naturally occurring peroxides with biological activities

Mini Rev Med Chem. 2003 Mar;3(2):159-65. doi: 10.2174/1389557033405313.

Abstract

New natural peroxides that have potent biological activities with novel diverse structures are reviewed with classification as secondary metabolites such as terpenes, polyketides, phenolics, and hydroperoxides. These compounds, isolated mainly from medicinal plants and marine sponges, are valuable sources in the drug discovery for particularly antitumor and antimalarial agents.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Antifungal Agents / chemistry
  • Antifungal Agents / pharmacology
  • Antimalarials / chemistry
  • Antimalarials / pharmacology
  • Antineoplastic Agents / chemistry
  • Antineoplastic Agents / pharmacology
  • Biological Products / chemistry*
  • Biological Products / pharmacology*
  • Enzyme Inhibitors / chemistry
  • Enzyme Inhibitors / pharmacology
  • Humans
  • Marine Biology
  • Peroxides / chemistry*
  • Peroxides / pharmacology*
  • Phenols / chemistry
  • Phenols / pharmacology
  • Plants, Medicinal / chemistry
  • Porifera / chemistry
  • Stereoisomerism
  • Terpenes / chemistry
  • Terpenes / pharmacology

Substances

  • Antifungal Agents
  • Antimalarials
  • Antineoplastic Agents
  • Biological Products
  • Enzyme Inhibitors
  • Peroxides
  • Phenols
  • Terpenes