Viscosamine: the first naturally occurring trimeric 3-alkyl pyridinium alkaloid

Org Lett. 2003 Oct 2;5(20):3567-9. doi: 10.1021/ol035006i.

Abstract

[structure: see text] Pyridinium alkaloids are widely distributed in marine sponges of different genera. Chemical investigation of the Arctic sponge Haliclona viscosa led to the isolation of a new trimeric 3-alkyl pyridinium alkaloid (viscosamine). Trimers have not been described as natural products yet. The isolation and the structure elucidation of viscosamine are discussed in detail.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkaloids / chemistry*
  • Alkaloids / isolation & purification*
  • Animals
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Porifera / chemistry
  • Pyridinium Compounds / chemistry*
  • Pyridinium Compounds / isolation & purification*
  • Spectrometry, Mass, Electrospray Ionization / methods

Substances

  • Alkaloids
  • Pyridinium Compounds
  • Viscosamine