Aptamer database

Nucleic Acids Res. 2004 Jan 1;32(Database issue):D95-100. doi: 10.1093/nar/gkh094.

Abstract

The aptamer database is designed to contain comprehensive sequence information on aptamers and unnatural ribozymes that have been generated by in vitro selection methods. Such data are not normally collected in 'natural' sequence databases, such as GenBank. Besides serving as a storehouse of sequences that may have diagnostic or therapeutic utility, the database serves as a valuable resource for theoretical biologists who describe and explore fitness landscapes. The database is updated monthly and is publicly available at http://aptamer. icmb.utexas.edu/.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Base Pairing
  • Base Sequence
  • Computational Biology
  • Databases, Nucleic Acid*
  • Genetic Engineering*
  • Internet
  • Oligonucleotides / chemistry
  • Oligonucleotides / genetics*
  • Oligonucleotides / metabolism*
  • RNA, Catalytic / chemistry
  • RNA, Catalytic / genetics
  • RNA, Catalytic / metabolism

Substances

  • Oligonucleotides
  • RNA, Catalytic