Abstract
We describe an efficient total synthesis of triciribine, a tricyclic nucleoside with antineoplastic and antiviral properties, starting from 4-amino-6-bromo-5-cyanopyrrolo[2,3-d]pyrimidine.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Antineoplastic Agents / chemical synthesis*
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Antiviral Agents / chemical synthesis*
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Humans
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Ribonucleosides / chemical synthesis*
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Toyocamycin / chemistry
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Virus Diseases / drug therapy*
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Viruses / drug effects*
Substances
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Antineoplastic Agents
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Antiviral Agents
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Ribonucleosides
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triciribine
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Toyocamycin