Abstract
Alkyl nitrones possessing N-substituted sugars as chiral auxiliaries were found to effectively undergo an SmI(2)-mediated radical addition to n-butyl acrylate affording gamma-amino acid derivatives with high diastereomeric control.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Acrylates / chemistry*
-
Amino Acids / chemical synthesis*
-
Carbohydrates / chemistry*
-
Free Radicals / chemistry
-
Models, Chemical
-
Molecular Structure
-
Nitrogen Oxides / chemistry*
-
Proteins / chemistry*
-
Proteins / pharmacology
-
Stereoisomerism
Substances
-
Acrylates
-
Amino Acids
-
Carbohydrates
-
Free Radicals
-
Nitrogen Oxides
-
Proteins
-
nitrones
-
sperm motility inhibitor 2
-
n-butyl acrylate