Seizure detection: evaluation of the Reveal algorithm

Clin Neurophysiol. 2004 Oct;115(10):2280-91. doi: 10.1016/j.clinph.2004.05.018.

Abstract

Objective: The aim of this study is to evaluate an improved seizure detection algorithm and to compare with two other algorithms and human experts.

Methods: 672 seizures from 426 epilepsy patients were examined with the (new) Reveal algorithm which utilizes 3 methods, novel in their application to seizure detection: Matching Pursuit, small neural network-rules and a new connected-object hierarchical clustering algorithm.

Results: Reveal had a sensitivity of 76% with a false positive rate of 0.11/h. Two other algorithms (Sensa and CNet) were tested and had sensitivities of 35.4 and 48.2% and false positive rates of 0.11/h and 0.75/h, respectively.

Conclusions: This study validates the Reveal algorithm, and shows it to compare favorably with other methods.

Significance: Improved seizure detection can improve patient care in both the epilepsy monitoring unit and the intensive care unit.

Publication types

  • Evaluation Study
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Algorithms*
  • Child
  • Child, Preschool
  • Cluster Analysis
  • Electroencephalography / statistics & numerical data*
  • Expert Systems
  • False Positive Reactions
  • Female
  • Humans
  • Infant
  • Male
  • Middle Aged
  • Monitoring, Ambulatory
  • ROC Curve
  • Seizures / diagnosis*
  • Seizures / physiopathology