Epidermal growth factor receptor in tumor angiogenesis

Lee M Ellis

doi:10.1016/j.hoc.2004.06.002

Epidermal growth factor receptor in tumor angiogenesis

Hematol Oncol Clin North Am. 2004 Oct;18(5):1007-21, viii. doi: 10.1016/j.hoc.2004.06.002.

Author

Lee M Ellis¹

Affiliation

¹ The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Box 444, Houston, TX 77030-4009, USA. lellis@mail.mdanderson.org

PMID: 15474332
DOI: 10.1016/j.hoc.2004.06.002

Abstract

This article focuses on the preclinical evidence for activation of the epidermal growth factor receptor (EGFR) in promoting angiogenesis and the efficacy of anti-EGFR agents in inhibiting angiogenesis and tumor growth.

Publication types

Review

MeSH terms

ErbB Receptors / antagonists & inhibitors
ErbB Receptors / physiology*
Humans
Neoplasms / blood supply*
Neovascularization, Pathologic / physiopathology*
Neovascularization, Pathologic / prevention & control

Substances

ErbB Receptors