Chaetoglobosins Q, R, and T, three further new metabolites from Chaetomium globosum

Wenxu Jiao; Yunjiang Feng; John W Blunt; Anthony L J Cole; Murray H G Munro

doi:10.1021/np030460g

Chaetoglobosins Q, R, and T, three further new metabolites from Chaetomium globosum

J Nat Prod. 2004 Oct;67(10):1722-5. doi: 10.1021/np030460g.

Authors

Wenxu Jiao¹, Yunjiang Feng, John W Blunt, Anthony L J Cole, Murray H G Munro

Affiliation

¹ Department of Chemistry, University of Canterbury, Private Bag 4800, Christchurch, New Zealand.

PMID: 15497948
DOI: 10.1021/np030460g

Abstract

Nine cytotoxic metabolites, including three novel compounds, chaetoglobosins Q (1), R (2), and T (3), have been isolated from cultures of the fungus Chaetomium globosum. The structures were elucidated primarily from NMR spectroscopic data.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Bacillus subtilis / drug effects
Chaetomium / chemistry*
Cladosporium / drug effects
Indole Alkaloids
Indoles / chemistry
Indoles / isolation & purification*
Indoles / pharmacology
Leukemia P388
Mice
Microbial Sensitivity Tests
Molecular Structure
New Zealand
Nuclear Magnetic Resonance, Biomolecular
Trichophyton / drug effects

Substances

Indole Alkaloids
Indoles
chaetoglobosins