Studies on the in vivo hypoglycemic activities of two medicinal plants used in the treatment of diabetes in Jordanian traditional medicine following intranasal administration

F U Afifi; B Al-Khalidi; E Khalil

doi:10.1016/j.jep.2005.03.016

Studies on the in vivo hypoglycemic activities of two medicinal plants used in the treatment of diabetes in Jordanian traditional medicine following intranasal administration

J Ethnopharmacol. 2005 Sep 14;100(3):314-8. doi: 10.1016/j.jep.2005.03.016.

Authors

F U Afifi¹, B Al-Khalidi, E Khalil

Affiliation

¹ Department of Pharmaceutical Sciences, Faculty of Pharmacy, University of Jordan, Amman, Jordan. fatueafi@ju.edu.jo

PMID: 15885943
DOI: 10.1016/j.jep.2005.03.016

Abstract

The claimed hypoglycemic activities of Paronychia argentea Lam. (Caryophyllaceae) and Teucrium polium L. (Labiatae), two traditionally widely used medicinal plants in Jordan were evaluated using normoglycemic and alloxan induced hyperglycemic rabbits by intranasal administration of the plant crude extracts (10%) in a vehicle containing 5% (w/w) Pluronic F127. No significant difference was observed between the extract treated and non-treated control animals receiving only water.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Administration, Intranasal
Animals
Blood Glucose / metabolism
Caryophyllaceae / chemistry*
Diabetes Mellitus / drug therapy*
Diabetes Mellitus, Experimental / drug therapy
Female
Hypoglycemic Agents / administration & dosage
Hypoglycemic Agents / pharmacology*
Jordan
Male
Medicine, Traditional
Phytotherapy
Plant Extracts / administration & dosage
Plant Extracts / therapeutic use
Rabbits
Teucrium / chemistry*

Substances

Blood Glucose
Hypoglycemic Agents
Plant Extracts