Influence of age of onset on clinical features in obsessive-compulsive disorder

Depress Anxiety. 2005;21(3):112-7. doi: 10.1002/da.20065.

Abstract

We compared early-onset and late-onset obsessive-compulsive disorder (OCD) patients in terms of demographic and clinical features. One hundred sixteen outpatients whose primary diagnosis was OCD according to DSM-IV diagnostic criteria were recruited. Early-onset (n=50) and late-onset (n=66) OCD groups were compared with respect to demographic variables and scores obtained on various scales. A male gender predominance was found in early-onset OCD group. Symmetry/exactness obsessions, religious obsessions, hoarding/saving obsessions, and hoarding/collecting compulsions also were significantly more frequent in the early-onset group than in the late-onset group. The results may suggest a phenotypic difference between the two groups. Further studies are needed to investigate the differences between early-onset and late-onset OCD groups to examine the hypothesis that early-onset OCD is a distinct subtype of the disorder.

MeSH terms

  • Adult
  • Age of Onset
  • Comorbidity
  • Demography
  • Diagnostic and Statistical Manual of Mental Disorders
  • Disease Progression
  • Humans
  • Logistic Models
  • Mental Disorders / diagnosis
  • Mental Disorders / epidemiology
  • Obsessive-Compulsive Disorder / diagnosis
  • Obsessive-Compulsive Disorder / epidemiology*
  • Obsessive-Compulsive Disorder / psychology*
  • Severity of Illness Index
  • Sex Factors
  • Surveys and Questionnaires